gmarx

25 ms·

241.
by gmarx 10y ago
I learned about that from the commentary on a LaserDisc of (I think) "The Graduate". The dick film professor mentioned the reel change circles and then said something like "now that I told you that you will always be consciou
242.
by gmarx 10y ago
You mean when the chromosomes are in their proper structures? What messes up the physical conformation of the chromosomes? Is it a combination of existing mutation and epigenitic mods? Or something else?
243.
by gmarx 10y ago
If you go via dementia by the time you get there you long ago lost the ability to act
244.
by gmarx 10y ago
Many people think that when they see an ill person. I wouldn't want to live like that. In reality it sneaks up on you so slowly that by the time you are in that situation, you do want to live like that. My dad saw his dad slowly die of
245.
by gmarx 10y ago
I enjoy how the article sometimes seems to have the point of view that this is the first time engineers ever had to work this way. I don't think they are taking software engineers and asking them to create drones. These seem like a lot
246.
by gmarx 10y ago
Makes sense. An interesting question is what causes the epigenetic modifications that drive the tumor forward. Do the driver mutations also cause these modification? Is it random and these cells are selected for?
247.
by gmarx 10y ago
I self funded a startup and worked by myself for a few years. I lost a tremendous amount of money. SOmehow the isolation enabled me to get a handle on the weight problem. I was down about 70 pounds by the end. Best $100K I ever spent :)
248.
by gmarx 10y ago
Deadlifting & squats worked for me
249.
by gmarx 10y ago
I ask myself would I have had the balls to do this, to stand up to the lawsuit, which I clearly couldn't afford? In my 20s maybe. Now probably not. It seems wrong that you can threaten whistle-blowers with stealing trade secrets. There
250.
by gmarx 10y ago
I kind of like "Hybris" even though I assume it was a typo. How about "deludbertise"?
251.
by gmarx 10y ago
Came here to make your second point. Most developers are bad and think they are good. I'll add that most of the people who provide requirements don't understand software development and most developers refuse or are unable to unde
252.
by gmarx 10y ago
I like UML diagrams for modeling entities. I haven't used the full set as part of a dev process in more than 10 years
253.
by gmarx 10y ago
Suppose it is a reaction to a viral infection you get when you are young which reactivates when you get older. It could even be that the initial infection is asymptomatic in many or most people and that only a small percentage of those infe
254.
by gmarx 10y ago
With all these stories what you believe or how serious you think it is (if you believe) depends on which party/candidate you support. The bar for "this is so obvious and simple and bad that I am changing my opinion of this person&
255.
by gmarx 10y ago
Why do you doubt that it is (or can be) caused by infectious agents, aside from the fact that in science doubt should be the default position. Is there evidence against it? My intuition is that it is more likely caused by an infection than
256.
by gmarx 10y ago
You can trust his advice based on his past record e.g. wasn't he the one who told Zuckerberg to abandon his music sharing ambitions and focus on Facebook? Or you could not trust his advice based on his record, e.g. his credulous invest
257.
by gmarx 10y ago
You've been right for years. Easy money has kept things stable but starting from right now, if you invest in stocks and bonds and hold for 20 years, you should expect pretty low returns. Everything is expensive
258.
by gmarx 10y ago
I get that but I am proposing to hard code the answer since I already know it
259.
by gmarx 10y ago
"There's an array of 10,000 16-bit values, how do you count the bits most efficiently?" multiply 10,000 by 16. There are 160,000 bits
260.
by gmarx 10y ago
Better multi lane information is great. I would also like better info on which lane to be in for a turn taking account of the fact that soon after I need to make another turn and don't want to have to cut across a lane to make it
261.
by gmarx 10y ago
I love the 4 armed drummer. There was such a character in the Nexus comics. The bass player is impressive using fingers. What is going on with the guitarist and all the tubes? Is a six string too difficult to play with robot fingers?
262.
by gmarx 10y ago
Many of the items the author claims China dwarfed Rome on seem pretty subjective. Philosophy and poetry? I didn't read very far past this. I am under the impression that Rome was pretty technologically sophisticated, even beyond what w
263.
by gmarx 10y ago
We don't have a lot of confidence about curing cancer near term (next decade or two). What we are really working on is turning it into a chronic condition, beating back recurrences occasionally with different therapies (and we hope wit
264.
by gmarx 10y ago
I don't think so. I'm sure there are epigenetic effects in cancer but I'm also pretty sure that cancers develop new mutations as they proceed. Ones that fool the immune system or chemotherapy agents get selected for and drive
265.
by gmarx 10y ago
The idea was that your body produces free radicals, molecules which are highly reactive because of an unpaired electron, caused a lot of damage to the body. The antioxidants sopped these up and prevented the damage. That was the hypothesis
266.
by gmarx 10y ago
So they agree that there is no evidence saturated fat causes health problems. Then they assert you should not eat processed food but fail to even assert a link to any specific health problems. Then they mention antioxidants which, if they h
267.
by gmarx 10y ago
The super rich have been doing this sort of thing at least since the robber baron era. Government funding of research went up dramatically anyway
268.
by gmarx 10y ago
yes but those people aren't silicon valley smart. Now that the tech billionaires are working on it we should have human health solved in a jiffy. It's like how medical informatics was in a pathetic state for decades until James Cl
269.
by gmarx 10y ago
That's doesn't even account for the probably larger number of bugs that develop over the lifetime of the system. Then, once a cancer develops it evolves further mutations over time. You probably cannot defeat cancer merely by gene
270.
by gmarx 10y ago
Will this evolve into a complete substitute for small talk? Will we some day have text algorithms exchanging pleasantries with our friends text algorithms each day? Hi John, how are you today? Wonderful! are you enjoying the 79 F sunny day?

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