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folli
searching PlanetScale…
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58 ms
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661.
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by
folli
8y ago
Could be a fun project, but I assume this would make motion sickness even worse due to delay and jitter in the smartphone's gyroscope.
662.
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folli
8y ago
Interesting article: https://www.theatlantic.com/health/archive/2015/11/the-caves...
663.
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folli
8y ago
I'm sure there exist a lot of One Person Companies that have much higher RPEs than $1M. They are of course not in the S&P 500, nevertheless it would be very interesting to read about them.
664.
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Google Play Store’s Algorithm Quietly Changes, Tanking Some Apps’ Rankings
(xda-developers.com)
31 points
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folli
8y ago
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7 comments
665.
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folli
8y ago
I wonder about a possible opposite principle: a person best suited for a role in leadership is stuck at the bottom of the hierarchy, because he's not fully competent at this current role, so he has no way to climb up.
666.
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folli
8y ago
This app is based on another app, where I've received some very helpful feedback from HN (Sun Locator), but this one focuses on the Moon location. I hope this will be helpful for photographers in planning photoshoots. Any feedback is a
667.
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Show HN: Augmented Reality App to Predict the Moon Location
(play.google.com)
1 points
by
folli
8y ago
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1 comments
668.
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folli
8y ago
You're right about the spelling, thanks for the heads up. Strange, the website doesn't use any Javascript, must be a CSS problem. Or possibly the embedded youtube video.
669.
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folli
8y ago
This is exactly why I started working on it. I wanted to know if and when the balcony of a potential new apartment will get any sunshine. There's also a free version of the app, to try it out: https://play.google.com/st
670.
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folli
8y ago
Thank you for the compliment and observations, I will relay it to the responsible web designer. P.S.: Give the app a try anyway. It's not only useful for photographers, I personally started working on it while looking for a new apartme
671.
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Show HN: Augmented Reality App to Predict the Sun and Moon's Location
(sunlocator.com)
21 points
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folli
8y ago
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7 comments
672.
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folli
8y ago
[De Beers] even developed a machine that spots lab-grown stones. How does that work? They should be indistinguishable.
673.
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folli
8y ago
Some would say the true rulers of Switzerland work in Brussels.
674.
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folli
8y ago
I'll be visiting Budapest in a couple of months. Are there any guided tours that you can recommend, diving a bit deeper into the history of Budapest?
675.
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folli
9y ago
Since we're splitting hairs instead of training sets: Classical RFs select one random feature and choose the optimal split, whereas Extremely RTs choose the best feature (out of a random subset) whereby for each feature only one random
676.
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folli
9y ago
In random forests you don't really need to find the optimal split. You usually generate a number of random splits and select the best one.
677.
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Pioneering autism researcher cooperated with Nazis, new evidence suggests
(sciencemag.org)
1 points
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folli
9y ago
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0 comments
678.
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folli
9y ago
If you know the seed and the used algorithm, you are already able to "predict" the pseudo-random sequence perfectly.
679.
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folli
9y ago
When people that actively remember anything before the year 2000, are in the minority. So I guess this applies to people born in the 80s (and before), so I assume this will be in the 2030s/40s.
680.
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folli
9y ago
In your analogy, Southern and Northern would be like using Fortran on a punched card, while high-throughput sequencing is using a modern programming language.
681.
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folli
9y ago
I agree with #1, although if you're associated with a university, you will most likely have access to it. I strongly disagree with #2, their news and opinions section is usually top-notch, well written and understandable (e.g. an artic
682.
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folli
9y ago
You're right that the precision of Cas9 is not a 100% (off-target effects), but 1) it is still magnitudes more precise than traditional breeding (where you have no idea what is happening and you only select by screening for selected ph
683.
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folli
9y ago
No, you can transfect the cells directly with Cas9 (the enzyme) and guide RNA, so you don't need to integrate the Cas9 gene into the genome, i.e. it won't be replicated and will vanish after cell division.
684.
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folli
9y ago
And how would you differentiate from classical breeding over X decades?
685.
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folli
9y ago
The precision will undoubtedly be increased. Remember that the system has been discovered approx. 10 years ago and the idea to use it for genome modifications (especially Cas9 from Streptococcus pyogenes) is only a couple of years old.
686.
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folli
9y ago
Using more traditional techniques, you insert a selection marker (e.g. an antibiotic resistance) which helps you selecting clones where the modification successfully took place (all the clones which do not have the antibiotic resistance wil
687.
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folli
9y ago
Resequencing of the modified genome is SOP, how else would you check that the right gene has been inserted/deleted in the right locus in the right way?
688.
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folli
9y ago
Deletion of a Gene -> Very high likelihood of occurring naturally Duplication of a Gene -> Very high likelihood of occurring naturally Insertion of a Gene from same species (e.g. from another strain) -> High likelihood of occurring
689.
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Ask HN: Alternatives to Stripe
8 points
by
folli
9y ago
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3 comments
690.
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folli
9y ago
Which payment processor would you recommend now? Edit: See also https://news.ycombinator.com/item?id=16772655
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