fasteo

69 ms·

1. 721.▲
   by fasteo 12y ago

   Chill out dude, I wasn´t implying anything but, using your words here, being "too lazy for instant noodles" seems like a problem to me. And yes, eating properly is fixing some of my health problems. And no, I am not talking about
2. 722.▲
   by fasteo 12y ago

   Better, but you've got a problem.
3. 723.▲
   by fasteo 12y ago

   Analyzing the effects on health of a single nutritional item - salt in this case - in pretty useless IMHO. The more I read about nutrition, the more I come to realize that it is the ratio of different nutrients what is key to our health. Ta
4. 724.▲
   by fasteo 12y ago

   I don´t think they have published any paper, but this kind of experiments are tricky. In the setup showed in the video (n=1, not blinded[1], no control group, no crossover), I would conclude that Jetpack does not work. The time differences
5. 725.▲
   by fasteo 12y ago

   I am happy to see that great craftsmanship in my compatriot. The spark in his eyes shows a passion that I - sanely, if that´s possible - envy.
6. 726.▲
   by fasteo 12y ago

   I guess it is easier to blame Oracle than to fire the truly incompetent managers of this project.
7. 727.▲
   by fasteo 12y ago

   The CRM/sales video is impressive. Congrats. After reading the HN tile, Zoho immediately came to my mind (maybe the starting Z? ). Are you targeting the same customers ? Zoho Creator looks similar in functionality.
8. 728.▲
   How Bacteria Distinguish Harmful versus Helpful Viruses(scicasts.com)

   1 points by fasteo 12y ago|0 comments
9. 729.▲
   by fasteo 12y ago

   We discussed this[1] yesterday, but this letter to the editor is worth reading. Lots of useful info for reading and understanding a scientific paper. [1] https://news.ycombinator.com/item?id=8263515 edited: One of the paper
10. 730.▲
    Devastating LTE apropos of the paper Methylphenidate exposure and neuron loss(plosone.org)

    1 points by fasteo 12y ago|1 comments
11. 731.▲
    by fasteo 12y ago

    Thanks for the hint. Our neuro suggested to halve the dose during weekends and holidays to avoid potential withdrawal symptoms
12. 732.▲
    by fasteo 12y ago

    Very high. How much time were you on that dosage ? Any bad side effect ?
13. 733.▲
    by fasteo 12y ago

    You are right. Drug metabolism is key here; that´s why I am not too worried about the results of this study. I have a child (24kg) with - properly diagnosed - severe ADHD on 20mg daily and the benefits clearly outweigh the potential risks;
14. 734.▲
    by fasteo 12y ago

    You cannot directly convert mouse to human doses. For this, you need to calculate HED[1] (Human Equivalent Dosage). Using your numbers: HED (mg/kg) = Animal Dose (mg/kg) x [Animal Km / Human Km] We use 3 for mice and 25 for h
15. 735.▲
    by fasteo 12y ago

    That would be also my plan, but once I have this setup, it would be impossible for me not to constantly switch between devices. Pairing every single time is actually a plus for me: It acts as a barrier to avoid multitasking in different dev
16. 736.▲
    by fasteo 12y ago

    Multitasking in a single screen is not a good idea. Multitasking in three screens can only make it worse. Very nice productivity killer though.
17. 737.▲
    by fasteo 12y ago

    I don´t have access to the paper referenced in the article, but a general rule applies: You have to be very cautious with the conclusions of a interventional nutritional study. There are lots of challenges[1] in the design, execution and
18. 738.▲
    by fasteo 12y ago

    Fair enough, and I agree with Dr. Morrow. My post was more about not confusing "à la carte" kids with mitochondrial DNA manipulation. I have read too many articles that fall into the "blonde, blue eyes and smart kids" ca
19. 739.▲
    by fasteo 12y ago

    Yeah, I feel kind of lucky these days, now that mitochondria seems to be at the center of every possible "aging" disease. Something good will happen sooner or later. The next milestone is the approval of EPI-743[1]. Phase III tria
20. 740.▲
    by fasteo 12y ago

    That´s also my understanding (and my hope). My bet is on heteroplasmic shift though. This will not actually "cure" the disease, but it will minimize its effects. Specifically, I am closely following the work with mitoTALENs [1]. I
21. 741.▲
    by fasteo 12y ago

    I did not want to comment in this thread as I am heavily biased and my opinion cannot be very objective, but let me just try to clarify some facts: About me: I do have a mitochondrial disease. In some of my cells, my mitochondrial DNA is no
22. 742.▲
    by fasteo 12y ago

    Picture of the back of that wall !!
23. 743.▲
    by fasteo 12y ago

    I would recommend his book [1] to anyone interested in systems performance. What really caught my attention is the focus he puts in having a goal and applying a method to solve performance issues. Many times, I have found myself "lost&
24. 744.▲
    by fasteo 12y ago

    How is this different from beanstalkd ? From the README file persistence seems like its main feature, but beanstalkd already has this (via a write-ahead log), along with priority, delayed jobs, burying/kicking jobs, TTR, explicit ACK (
25. 745.▲
    by fasteo 12y ago

    Radar rat race. That's all.
26. 746.▲
    by fasteo 12y ago

    A feature that you don't like is still a feature
27. 747.▲
    Gut Bacteria: Now Assuming Control Of Your Brain(science20.com)

    1 points by fasteo 12y ago|0 comments
28. 748.▲
    Stop-the-beauty-madness ad campaign(stopthebeautymadness.com)

    3 points by fasteo 12y ago|0 comments
29. 749.▲
    by fasteo 12y ago

    Strange question. This is what HN is all about. Telling histories that might be of interested to the community. This one is no exception.
30. 750.▲
    by fasteo 12y ago

    There are highly conserved molecular structures that made it to our DNA. This is a good hint about the common origin of life. Due to my genetic defect in the mitochondrial respiratory chain (ETC), this one[1] caught my attention. Apart from