ethbro

10 ms·

121.
by ethbro 6y ago
> Makes you wonder wtf Chinese virology labs were doing for 20 years with coronavirus if they weren't working on a cure, doesn't it? (There's 40 labs total across China.) Like most things in a command economy, they worke
122.
by ethbro 6y ago
Non technical folks under-appreciate the cost and frequency of long-term technical debt. It's easy to save money on developers, yet very quickly produce a net-negative result for the company. Sadly, few companies have guardrails to pre
123.
by ethbro 6y ago
The ultimate take-away from "Mythical Man Month" is that the limit of adding people is not zero extra-work-per-additional-person, but unbounded negative extra-work-per-additional-person.
124.
by ethbro 6y ago
You see how that language was carefully crafted with "develop" and "promote" / "encourage", vs the "maintain" and "take" in Article 1.1 and portions dealing with peace? The UN exists to
125.
by ethbro 6y ago
> The UN hasn’t prevented nuclear war, it’s accomplished virtually nothing in its long history. Last "nuclear war" was on 9 August 1945. UN formed on 24 October 1945. > Geopolitical reality doesn’t require letting authori
126.
by ethbro 6y ago
> Using an SCM tool isn’t going to cause additional problems except for reminding yourself of all the dumb mistakes you made last week. You haven't worked at a shop that mandated Team Foundation Server, have you? ;)
127.
by ethbro 6y ago
That's pretty canon. I might put a comma after anything, but that's more personal preference / feel than grammar.
128.
by ethbro 6y ago
And I suppose these were rescue pirates? https://brickset.com/sets/1481-1/Pirates-Desert-Island https://brickset.com/sets/1970-1/Pirates-Gun-Cart https://brickset.com/set
129.
by ethbro 6y ago
And many software developers don't properly use a CVS. But that doesn't make GitHub a bad idea.
130.
by ethbro 6y ago
You're leaving out all choices in your decision pipeline. If you screen positive, you can elect to have a biopsy or scan. If your results come back inconclusive, you can elect to pursue surgical (or other) intervention. That's wha
131.
by ethbro 6y ago
Time provides options in cancer. Even if the first option is "get more regular checkups over the next year+, to characterize the growth rate." You don't have to nuke an organ from orbit, if you have historical data that indic
132.
by ethbro 6y ago
European (generalizing) models seem to have the problem that they generalize restrictions while specifying permissions. E.g. 'Thou shalt not store & use personal data' Overridden by 'Thou may store and use personal data,
133.
by ethbro 6y ago
Expect it'll be quite some time before there's enough open-market inventory available that we have the option to shop (2H 2021). Governments have too much incentive to purchase and distribute all they can get their hands on.
134.
by ethbro 6y ago
It won't get a trade name until it goes to market. We just don't normally hear about pre-market drugs in mainstream media.
135.
by ethbro 6y ago
Yeah, this is one big thing that's pulling the delivery times closer vs historical timelines. Governments essentially said "If you can demonstrate reasonable efficacy and safety, go ahead and start mass production. If your Phase I
136.
by ethbro 6y ago
Chimpanzee adenovirus-vectored Oxford vaccine #1, targeting novel coronavirus 2019 (aka SARS-CoV-2). Seems pretty well-named.
137.
by ethbro 6y ago
From the Moderna Phase I results published recently [1], I'd point out that most vaccine candidates are also performing antibody challenges and T-cell counting, to better characterize the effective immune response generated [2], beyond
138.
by ethbro 6y ago
Technically, it's only illegal against older workers Specifically, discriminating against someone over 40 due to age. (29 USC § 621: https://www.law.cornell.edu/uscode/text/29/621 )
139.
by ethbro 6y ago
China's economy looks very different if the world starts treating them differently. All while they're attempting to transition their economy from lowest-cost manufacturer to value-add. It's benefited from 20 years of optimist
140.
by ethbro 6y ago
I have family in pathology. Labs do a lot of sample sectioning before microscopy. Thin enough to stain and visualize internal structures (think onion skin). PS: Never mention anything about this around TSA.
141.
by ethbro 6y ago
https://en.wikipedia.org/wiki/Glass_knife#Modern_use
142.
by ethbro 6y ago
Naval construction history has odd connections too, as one might imagine: https://en.wikipedia.org/wiki/Krupp_armour
143.
by ethbro 6y ago
For anyone who hasn't, would highly recommend. Railroad spikes are cheap and easy to hammer. Not great steel, but great for practicing metalwork.
144.
by ethbro 6y ago
That's the problem with state-driven investment. Most people are lazy and/or greedy, and given a known state-sponsored payday, have no incentive to deliver quality. So even if the Chinese state may want the projects to go well, th
145.
by ethbro 6y ago
But can they afford to fund it alone? The Soviet Union didn't collapse because a lack of capability. They collapsed because it was too expensive to forge their own way, when most of the world could pool capital via free trade. China is
146.
by ethbro 6y ago
> semiconductors don't hit big conservative wallets and their motivations The military.
147.
by ethbro 6y ago
"A lot closer than most people realise" != the same.
148.
by ethbro 6y ago
Derek Lowe's base blog is better, and more active, currently: https://blogs.sciencemag.org/pipeline/
149.
by ethbro 6y ago
> Probably referring to the fact the majority had fairly noticeable side effects especially with the second dose. Did anyone look at the actual data? [1, Table S1-S3] At the 100 μg 2nd dose, the most frequent moderate symptoms were fat
150.
by ethbro 6y ago
Messaging is written by marketing and sales departments. Employees there usually don't have depth of technical expertise or experience to draw from, and are incentivized to make the product sound as easy to use as possible. This combin

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