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https://en.wikipedia.org/wiki/Glass_knife#Modern_use https://en.wikipedia.org/wiki/Glass_knife#Modern_use
by ethbro 6y ago
https://en.wikipedia.org/wiki/Glass_knife#Modern_use https://en.wikipedia.org/wiki/Glass_knife#Modern_use
- lioeters 6y agoFascinating! > [Glass knives] were once the blade of choice for the ultra-thin sectioning required in transmission electron microscopy because they can be manufactured by hand. > ..Some labs still use glass knives because they are significantly less expensive than diamond knives. A common practice is to use a glass knife to cut the block which contains the sample to near the location of the specimen to be examined. > Then the glass knife is replaced by a diamond blade for the actual ultrathin sectioning. This extends the life of the diamond blade which is used only when its superior performance is critical. > Obsidian, a naturally occurring volcanic glass, can also be used to make sharp glass knives; obsidian surgical scalpels are available commercially.
- ethbro 6y agoI have family in pathology. Labs do a lot of sample sectioning before microscopy. Thin enough to stain and visualize internal structures (think onion skin). PS: Never mention anything about this around TSA.