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70 ms
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571.
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by
entee
11y ago
A lot of the things we associate with semiconductors is actually chemistry, i.e. photoreactive resists, proper surface deposition of various layers of metals. Also usually referred to as a joke, but "Plastics." How many things aro
572.
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by
entee
11y ago
No question scientific publishers are effectively a racket. The problem is that as a researcher you're stuck. If you want tenure, you need a publication in a big journal. There are a few that are open access in some domains, notably bi
573.
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by
entee
11y ago
Absolutely. Membranes will foul, things will clog, it's basically doomed in a developing world environment. Re. Service contract/rental model, the economics of providing that service are extremely challenging. People who need this
574.
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by
entee
11y ago
Agreed. Applying the terminology of traditional consumer tech to Biology/Biochemistry is both conceptually incorrect and deeply problematic. I've been doing molecular biology professionally for nearly 10 years now, I don't th
575.
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by
entee
11y ago
It's really hard to figure out whether to trust this study, I can't find a link to anything that's been published/peer reviewed on the OP link. These kinds of epidemiological studies are incredibly difficult, and easy to
576.
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How to fight inequality with stocks
(politico.com)
2 points
by
entee
11y ago
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1 comments
577.
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by
entee
11y ago
It's easy to forget how a "historic place" is actually not that old. Cities are constantly changing, we'd do well to not let preservationist instincts always trump new development and changes for a more useful city. SF i
578.
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The Man Who Tried to Kill Math in America
(theatlantic.com)
2 points
by
entee
11y ago
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0 comments
579.
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by
entee
11y ago
A lot of the things they've claimed to be developing (microfluidic devices, signal amplification strategies, novel assays, etc.) are totally patentable. Maybe they don't want to reveal their secrets to inhibit competition, but in
580.
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by
entee
11y ago
Index funds are by all evidence the better choice for the average individual, but they present something of a chicken and egg problem. To set the price of the index, you need people buying and selling individual stocks. If everyone owned in
581.
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by
entee
11y ago
I'm pretty sure preimplantation diagnostics are in many cases done with next-gen sequencing these days. Also even accepting the idea that GWAS studies for IQ yield real and useful results (a claim most people I know in the human geneti
582.
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by
entee
11y ago
Genetic medicine is a tough problem. CRISPR isn't a panacea, and if I had to place bets, it's primarily going to massively accelerate basic biological research rather than itself be a clinical tool except in certain limited contex
583.
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by
entee
11y ago
I think CRISPR is a breakthrough for sure, it's quite unclear whether it will be "fundamental". It's a fantastic research tool. Clinical applications however are quite a bit more challenging and at least in its current i
584.
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by
entee
11y ago
I think it's quite dangerous when there's a company that says "we have breakthrough science, but we definitely can't tell you what it is", which was Theranos's M.O. for a long time. Working in medicine is hard,
585.
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by
entee
11y ago
There are periodic "devastating" events in the valley, maybe not quite as bad but there is a boom-bust cycle in the valley does something similar. The selection bias for positive outcomes is pervasive. There were many, many appren
586.
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by
entee
11y ago
Thanks! Much appreciated :)
587.
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by
entee
11y ago
Every time I see something with Wolfram Language, I'm fairly impressed with how powerful it seems. But then I wonder, is that just because I see people who are skilled in the art or is it intrinsic to the language? If it is so powerful
588.
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by
entee
11y ago
I have found one advantage of startups as an employee if you want to start your own company down the road is that you get to see easy-to-make management mistake and their repercussions. In a big company, there are systems and structures in
589.
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by
entee
11y ago
True, but the marginal cost of oil is cheaper still, and when building a new plant it's even easier to have massive cost overruns due to unforeseen complications in building the plant. As an aside: someone in the oil industry once told
590.
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by
entee
11y ago
Obviously more expensive carbon-intensive fuels favors renewables, but I wonder what the threshold is to really give a long term incentive for innovation. For a lot of renewable energy technologies, the biggest problem is operating at a lar
591.
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by
entee
11y ago
The point about people in rent controlled apartments having very little incentive to favor increased density is a different one than I've heard, and a telling one. If between owners and rent-controlled apartments you have a large votin
592.
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by
entee
11y ago
I've always been curious about docstring style. I've usually gone with numpy-style docstrings: https://github.com/numpy/numpy/blob/master/doc/HOWTO_DOCUMEN... They tend to be easier to rea
593.
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by
entee
11y ago
I've been asked several times before why we don't use more "kill-it-dead-forever" (another way to look at covalent inhibitors like Ibrutinib) Covalent inhibitors are quite tricky to work with because every drug, no matte
594.
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by
entee
11y ago
There are some tools out there, for example Open Babel: http://openbabel.org/wiki/Main_Page which has some python bindings built in. I set some of this up for myself during my PhD but it was occasionally kind of a pain
595.
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by
entee
11y ago
They've hired some really heavy hitters in biology, but that's about all this article reveals. Would be nice to know what they're doing, given the extremely strong academic pedigree for some of these guys I wonder if they
596.
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by
entee
11y ago
I've often wondered how CRISPR is actually useful, because at its core it's just a nuclease. It allows to you precisely cut DNA where you want to cut it. But for that to be useful you still have to put the DNA back together afterw
597.
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by
entee
11y ago
I don't think data science for health is in any way limited to wearables. I think this is the first time we've had the opportunity to do real data science at a massive scale with patient data of all sorts, including electronic med
598.
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by
entee
11y ago
The hardest thing about algal fuels is keeping your bioreactor working at peak efficiency. This is quite difficult, consider the following: Problem: Outside organisms keep contaminating your pools of algae. Solution: cover them up. Problem:
599.
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by
entee
11y ago
Not necessarily. It's entirely possible to be a great engineer and a terrible CEO/Founder/Mentor. It's obviously not always true, but I think there's a benefit to age and wisdom. It's easy(ish) to find someone
600.
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by
entee
11y ago
Oh totally. I think it would be a bad thing overall, but that doesn't mean it won't happen. If you have enough capital in a relatively small number of private entities, perhaps they will find it to their advantage to compromise a
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