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searching PlanetScale…
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65 ms
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601.
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by
entee
11y ago
Possibly also illegal though from a document preservation perspective.
602.
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by
entee
11y ago
My guess is for these things to change (if they ever do) there would have to be a crisis event. Maybe after the next crash employees will be more reticent to take pure stock and will go for an alternate arrangement. Maybe the structures bui
603.
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by
entee
11y ago
Cool, thanks! That said I wonder if 1 will always be that big an issue. What if you structure it so that you have a small number of large shareholders that represent larger groups? For example, in the case of stock options, a sort of labor
604.
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by
entee
11y ago
I'm curious given these kinds of deals, what the point of an IPO is anymore? For some of these companies the valuations are so high, and private capital so available that it seems incredibly unlikely that they'd get a better deal
605.
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by
entee
11y ago
It also correlates closely with the advent of smart mechanized labor (mostly dumb robots), which of course requires computers, but I think more of a problem. You need a fraction of the number of people to put together a car as you needed in
606.
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by
entee
11y ago
No diversity = blind spots. How many startups aren't serving needs because they're simply not the needs of those founding the company? And how many are missing the bigger picture on the product because they don't have someone
607.
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by
entee
11y ago
It seems the author is discouraging the practice of staying up all night but not throwing it out entirely. In my reading the article suggests that this shouldn't be the rule but leaves space for times when it may be required, or not so
608.
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by
entee
11y ago
Really interesting take, very much in line with my experience that scientific code is often broken from a software engineering point of view. Science benefits greatly from using more standard toolkits in open languages instead of proprietar
609.
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by
entee
11y ago
I too wish there were more out of the box solutions for these. I also wish more keyboards separated the keypad from the main keyboard. I like to stay centered in front of the monitor, which means necessarily the number pad makes the whole t
610.
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by
entee
11y ago
I actually spoke with one of the principals at the company last weekend. I'm still not entirely sure it's a real effect, but he was telling me that they have mouse models that are incredibly impressive. That said, cancer has been
611.
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by
entee
11y ago
This kind of study is very cool, but not without some controversy. There's some debate whether knowing how everything connects to everything else at a single neuron level is as informative as we once hoped, because the brain seems to b
612.
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by
entee
11y ago
There's a lot of structure in how the brain is wired that is is baked in when you're born. The visual cortex is in the back, the hippocampus is in the middle, the frontal cortex is in the front. You do have unsupervised learning,
613.
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by
entee
11y ago
True. However we know shockingly little of how neurons actually do computation. Everything a neuron does it does so with a combination of electrical and chemical signals. This is why it's slow, but it also introduces considerable noise
614.
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by
entee
11y ago
Gold and mercury form an amalgam, so you would still have had something that looks like a big hunk of metal. I suppose you wouldn't have known whose gold that was, but the fact that you had a large chunk of gold-mercury amalgam in the
615.
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by
entee
11y ago
Speaking from the perspective of life science, I think the idea of the "article" and "review" as two separate complimentary parts of constructing knowledge actually makes a lot of sense. An individual article is an argum
616.
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by
entee
12y ago
I would add the very large old codebase in science. These systems gained popularity well before the advent of Python and other more user-friendly/approachable languages, so very large numbers of people in academia are familiar with the
617.
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by
entee
12y ago
I don't think that's true at all. The trouble is the aspirin is free. Node, jQuery, Python, pick-your-language-or-framework, almost all are free. The point of the article is that if you want to make a pain killer, it better be vic
618.
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by
entee
12y ago
I believe the scientist you're talking about is Ben Barres at Stanford. I know people who have worked for him and he's a truly exceptional scientist and mentor. He's been pretty outspoken about his personal experience on how
619.
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by
entee
12y ago
I think this is only partially true. It's really a case of what you worked on, where you worked on it, and who you did it with. For example: a lot of Biochemistry and Dev Bio these days relies at least in part on so-called next-generat
620.
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by
entee
12y ago
I think the downside of no PhD is that you're much more likely to hit a glass ceiling. There are obviously exceptions but you're more likely to be put in charge of a research project in industry if you have a PhD than not. Clearly
621.
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by
entee
12y ago
Fair enough, but if you buy a lot of the mayo products in the condiments aisle, the FDA doesn't think you're getting it. Check it out next time you're in the supermarket, lots of things are dressing and not mayonnaise, but I&
622.
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by
entee
12y ago
Neither are a lot of Hellmann’s products. Lots of their products are called "mayonnaise dressing" instead of "mayonnaise" probably because they don’t fit the criteria either. Do you care though? You probably never notice
623.
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by
entee
12y ago
I think the point is not whether it fits the current standard but whether those standards make sense in an age of innovation. I think consumers are smart enough to figure out whether or not the product they bought is mayonnaise. If it taste