entee

61 ms·

481.
by entee 10y ago
Presumably as with today, you'll have the option. I don't have a strong opinion on case sensitivity of file names, but I suspect they'll keep it case insensitive by default. I think for the average non-technical user that two
482.
by entee 10y ago
Maybe, though she's already not the stereotypical rich white young male founder. She does check 2/3... I still think the story of the rather epic rise and fall of a company that promised so much, achieved an insanely high valuatio
483.
by entee 10y ago
Absolutely. Humans aren't mice. That doesn't mean mouse studies aren't enormously helpful, but it does mean that we should take things with a grain of salt. The complexity of even a mouse is pretty enormous, and humans are th
484.
by entee 10y ago
This article gives a great overview of a fascinating field, and does so fairly responsibly, which is unusual in the popular press. From the end: '“Too many large-scale, spurious claims are being made,” Dinan said, mostly by people with
485.
by entee 10y ago
But to get the best sales people you have to give them something easy to sell! Doesn't sound like Twitter is easy to sell compared to FB.
486.
by entee 10y ago
The idea that Western Educated Industrialized Rich Democratic (WEIRD as stated in the article) studies are biased is both obvious and not necessarily entirely problematic. The reasons it's not so bad are 2 fold: 1.) Scientists know thi
487.
by entee 10y ago
Good post. I'm curious about something else in addition. I've heard from friends in teaching that there has been a massive increase in administrative overhead and concentration of power both at the school district (superindents, s
488.
by entee 10y ago
Neural nets are fantastic, but not all problems either require or are best solved by neural nets. Sometimes you want to understand more deeply how certain variables contribute to the prediction. That's not as trivial to do with neural
489.
by entee 10y ago
But as you rightly point out that costs money. I've been thinking about paying for some of the sites I use frequently but if you add up $5 a bunch of times you get to pretty big numbers per month. Also $5 for one website? That's 1
490.
by entee 10y ago
I don't think it's hypocritical to say a job is difficult and also to say that you want to keep that job. Automation may or may not be a good idea, but I think it's important to be compassionate about those who we lose their
491.
by entee 10y ago
More data is more better. Imaging is nice, but it's really hard to do biochemical tests via imaging. It can be done but hasn't been much so far outside the lab. Implanted samplers are cool, but they get fouled up pretty easily and
492.
by entee 10y ago
Indeed, and never forget the false positive paradox: https://en.wikipedia.org/wiki/False_positive_paradox
493.
by entee 10y ago
I think you're right, it's someday possible, but it's quite early days. The danger of over-promising in medicine is that when you fall flat, in the best case you badly damage the pipeline of people trying to solve it, and in
494.
by entee 10y ago
This article points out the major issue in blood testing: it's not a panacea. So often, particularly outside the life-sciences press, the idea that we'll be able to test for everything and that it will be useful gets shouted from
495.
by entee 11y ago
I think the idea is to avoid NHEJ entirely. I would guess that it's going for base-excision-repair (BER), which is why it's currently targeting either C or G bases. If the wrong guide sequence is bound you're screwed no matte
496.
by entee 11y ago
A major issue is that in vitro you have the luxury of many attempts to get the right result. Here's a somewhat simplified but illustrative example: Say you have 10 mouse embryos. You use CRISPR, then check them for whether it worked ou
497.
by entee 11y ago
The paper takes CRISPR/Cas9 and turns it into a targeting system for an set of enzymes that allow modification of a single DNA basepair at a specific locus in the DNA without introducing a double strand break. The reason this is import
498.
by entee 11y ago
I agree with most of what you're saying, but I think labs with more professional scientists (Research Scientists as opposed to postdocs and grad students) might be the way of the future and a Good Thing. There are obviously too many Ph
499.
by entee 11y ago
Sounds like a plan, I like it. Trouble is that to do that you'd have to have relatively sophisticated NLP to figure out what was the topic. On the other hand perhaps a simple comparison of keyword frequencies in title or all comment bo
500.
by entee 11y ago
I think a great many people who would consider themselves Keynesians are rather pro free-trade. I'm thinking here of Paul Krugman who despite have recently backed off saying trade is universaly good has been very much pro free trade. I
501.
by entee 11y ago
Generally I agree with the Keynesians, but I'm skeptical that the main explanation for the stagnation in median wages (employment has gone up and down, was down to 4% in the late 90's) we have observed for past several decades is
502.
by entee 11y ago
I like the idea. One thing though, this won't work unless people vote. A major reason the system doesn't work well today is because only the most extreme voters turn out for primaries. Even if you reduce gerrymandering, it's
503.
by entee 11y ago
Generally I agree with the Keynesians, but I'm skeptical that the explanation for the stagnation in median wages (employment has gone up and down, was down to 4% in the late 90's) we have observed for past several decades is due t
504.
by entee 11y ago
All true. Thing is though, it's not about Ted Cruz, or Obama or even the congress. Sure, it's a problem at those levels, but it's a REAL problem at the state and local level. As a super PAC you can have a much larger influenc
505.
by entee 11y ago
Perhaps the least understood view of lobbying that really informs how perverse the system has become is that as a general rule people believe the lobbyists are calling the congresspeople to offer them money. In reality, it's the congre
506.
by entee 11y ago
My argument is not that government is inefficient and so it shouldn't be used, my argument is that despite inefficiencies it's appropriate to use in certain cases because the alternatives are worse. I think with regards to healthc
507.
by entee 11y ago
Possibly, but particularly for interstate issues it's hard to see how that works. And even where it does, it's usually slow and difficult to scale. The first thing that comes to mind is environmental issues. These have national im
508.
by entee 11y ago
I think I can see a case for getting out of providing pensions, but I would respectfully disagree about broadly getting out of healthcare and education. Certainly in certain subsections of those areas there is much to improve and perhaps le
509.
by entee 11y ago
Very much agreed! I've rarely heard people working at big corporations say, "Wow everything we do is so free or red tape and full of efficiency!"
510.
by entee 11y ago
Jupyter is great for prototyping and playing with ideas, essentially its great it you want persistent data. But after you more or less know what you want and loading the initial dataset isn't a constant annoyance you're usually be

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