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Absolutely. Humans aren't mice. That doesn't mean mouse studies aren't enormously helpful, but it does mean that we should take things with a grain of salt. The
by entee 10y ago
Absolutely. Humans aren't mice. That doesn't mean mouse studies aren't enormously helpful, but it does mean that we should take things with a grain of salt. The complexity of even a mouse is pretty enormous, and humans are that much more confusing.
As for gut to brain transmission, the first thing that comes to mind is being hangry but that's probably a different thing :)
- rixed 10y agoWhy would human guts be that much more confusing than nice guts?
- tremon 10y agoFor one, we have twice the number of bacterial species. But it seems more important to me that only 4% of the microbiome is shared between humans and mice. http://www.nature.com/nbt/journal/v33/n10/full/nbt.3353.html http://www.nature.com/nbt/journal/v33/n10/full/nbt.3353.html
- rixed 10y agoThat second argument does not imply that humans are more confusing than mice, just different. My reaction was only against the apparently underlying assumption that humans, biologically, are more complex than mice, a remain of the idea that they are more evolved or a biased perspective due to the fact we study them in more detail.