entee

63 ms·

511.
by entee 11y ago
I think people neglect how much centralized regulations and processes can reduce cognitive load. Perhaps there's increase cost to the individual regulation, but the reduction in cognitive load and wasted time likely offsets that cost s
512.
by entee 11y ago
The government isn't the most efficient organization in the world, but for some problems it's the only kind of organization that can reasonably address the problem. If there isn't a plausible alternative organizational struct
513.
by entee 11y ago
Absolutely. If everyone voted, there would be far more incentive to please the most number of people, not just the most invested in the status quo, or some other ideological view.
514.
by entee 11y ago
Voting in primaries is the single most important thing anyone can do do improve the political situation not just in SF but in the country writ large. As the article states, there's a large majority of the population in favor of relativ
515.
by entee 11y ago
Fixed, thanks!
516.
by entee 11y ago
This is true. However it's important to add that state income taxes are deductible on your federal return. While this doesn't entirely offset the imbalance, it does mean that the federal government indirectly subsidizes states wit
517.
by entee 11y ago
The Randian view of this is just not very productive. Let's take a Randian hero, a self-made man (and it seems to always be men in her world) who is super creative, independent and gets shit done. Maybe he runs a construction company.
518.
by entee 11y ago
Wow that chart is astonishing, and in the context makes the headline a little misleading. Having a such a small percent pay such a huge share is toxic. I've heard people who pay high taxes say incredibly entitled things about "pay
519.
by entee 11y ago
Coupling small molecules to antibodies is tricksy :-P. There have been a lot attempts at doing that (the first I recall is from the late 90's but possibly even earlier), but not many have made it into actual clinical practice. Turns ou
520.
by entee 11y ago
Yeah the brain is a privileged site, a fancy way of saying it's not like places that have ready bloodflow with very little to separate the organ. The blood brain barrier is a real problem in drug development, but it's not that sur
521.
by entee 11y ago
Don't think this was around when I went there, but I'm super excited that it is. I did take a Software Engineering course while I was there that directly interacted with real-world clients and had to ship customer ready software a
522.
by entee 11y ago
It's not just about patience, there are a lot of guidelines and hurdles to jump through to be eligible for certain contracts. Some of this is for good reason, there have been plenty of cases of contractors bilking the government out of
523.
by entee 11y ago
I think part of this stems from the nuttiness that is government contracting and the massive organizational sprawl inherent in our current governmental structure. Looking at some of the details it seems some agencies are somewhat better tha
524.
by entee 11y ago
The research tends to back this up. The valley tends to be quite youth-obsessed but in reality successful founders of companies tend to be a little older than 25: http://www.kauffman.org/what-we-do/research/2010&#x
525.
by entee 11y ago
Is this a side-effect of mobile devices having extremely tight requirement for power usage and packaging? I could see how that, and a huge number of functions being packaged into a single SOC would make each board design far less generaliza
526.
by entee 11y ago
There are actually ways to make it so it will in fact stop when contact with one's hand (for saws but you could see an analogous system for a drill press): http://www.sawstop.com/why-sawstop/the-technology Just be
527.
by entee 11y ago
I have used JSON types in Postrgres for a little while now, they're pretty great! I can't really see a downside, is there a disadvantage to this kind of setup? In our use case there were very clearly parts of the data that were re
528.
by entee 11y ago
That's not strictly true, the board composition was far more traditional prior to 2013, a lot of these government guys came on at that point. From the wikipedia article: https://en.wikipedia.org/wiki/Theranos In J
529.
by entee 11y ago
It's still an annoying process. As someone who didn't itemize but had some weird tax situations (PhD student) it was always a pain. Also even if you have a drop dead simple tax situation, it's still navigating and filling out
530.
by entee 11y ago
I'd love to find some of those too, but brief searching didn't yield anything. In general though, it seems some of the most popular itemized deductions are: 1.) Deduct state income tax 2.) Mortgage interest 3.) Child-oriented tax
531.
by entee 11y ago
Anti-tax advocates are opposed to this kind of measure for 2 reasons: 1.) If we make it easy to file taxes, that means it's less painful and makes it harder to sell the cause of lower taxes as a political issue. 2.) If a citizen gets a
532.
by entee 11y ago
The tax code is this way because in practice everyone wants it to be this way. We spend through the tax code instead of directly paying for things because it's a lot easier to sell politically. People say some variation of, "Make
533.
by entee 11y ago
Neutral probably, might affect costs at IRS, but I would imagine relatively little change in revenue. The hiccup could be if people were consistently overestimating their taxes, but it looks as though for the median citizen that's unli
534.
by entee 11y ago
I think there's plenty of evidence to question their honesty as a company :-P You're right there are a few labs they do on commercial hardware that does work, and I think they're allowed to provide a test (for Herpes I think?
535.
by entee 11y ago
Frist makes sense on the board in that he definitely knows who to call at the FDA and would get his call answered. As unsavory as it is, lobbying experience is valuable in tightly regulated industries. I have no idea if he's a good doc
536.
by entee 11y ago
Lots of things are quick, simple and painless, but also utterly useless. If the labs don't work, how did they prove it could be all of those things? I like public prices and a nice phone app, but that's completely peripheral to th
537.
by entee 11y ago
That's fair, absolutely if you put it that way then yeah MVPs are much more frequent. I think I see the experiments you're doing more as internal development. I.e. I run bits of my code dozens of times a day to make sure it's
538.
by entee 11y ago
That makes some sense, though it seems they'd have to deliver something in that case. I'm sure one could keep the charade going for a little bit by delaying/delivering stuff that didn't work, but eventually the docs in t
539.
by entee 11y ago
I heard from a friend who is fairly prominent in the microfluidics space (doing lab work with much smaller amounts of material than ordinarily required) that initially it was a drug delivery company. Delivering compounds in a reliable time
540.
by entee 11y ago
I'm a little confused, does the military acquire companies wholesale? I've never heard of that happening, that's not to say it can't but what are some examples of this kind of scheme? Instead was the plan to milk the mil

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