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dekhn
searching PlanetScale…
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12 ms
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271.
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by
dekhn
7mo ago
Tim Apple is like Larry Ellison; don't make the mistake of anthropomorphizing him. Simply think of him as a robot that is designed to make apple more profitable. Greasing the Trump skids helps with that.
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dekhn
7mo ago
You sound awfully confident about this, given we have no direct evidence for most of your claims. I would find your writing more convincing if you didn't make absolute statements.
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dekhn
7mo ago
I don't think wikipedia is the best reference here, and I think you're also misinterpreting them; not all carbon-containing substances (including diamond) are considered organic. There is no true classical definition of the term-
274.
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dekhn
7mo ago
Fauci didn't work for the FDA. If you have a point/agenda, simplest to just state it out loud.
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dekhn
7mo ago
I mean, I don't think diamonds are considered "organic"; same for graphite. But that's where the term "organic" itself starts to break down as a category.
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dekhn
7mo ago
Yes! Not sure why you're asking- things don't have to be created by biological processes to be organic (this concept is totally unrelated to "organic" in the supermarket).
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dekhn
7mo ago
See buckyballs as a trivial refutation of your point.
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dekhn
7mo ago
We used to joke in my biophysics grad program that basically everything was determined by its surface area to volume ratio.
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dekhn
7mo ago
We switched to talking about llmfit in this subthread, it runs as native code.
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dekhn
7mo ago
How could it not? That information is always available to userspace.
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dekhn
7mo ago
https://www.cnn.com/TECH/computing/9904/08/cdrom.idg/ and https://forums.civfanatics.com/threads/wow-what-a-system-ftp... I'm not aware of any others with more details and
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by
dekhn
7mo ago
Your comment reads as negative about the corporations even if that's not what you intended. There's something about the way it's reads (I noticed myself when I read your comment, then noticed your edit at the bottom). Nuanc
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by
dekhn
7mo ago
The same joke is in David Macauley's Motel of the Mysteries (see drawing in https://www.byanyothernerd.com/2020/04/stranger-days-39-myst... ).
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by
dekhn
7mo ago
Note that my field is biophysics (quantitative biology) while yours is physics and CS. Those are done completely differently from biology; with the exception of some truly enormous/complex/delicate experiments that require unique
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by
dekhn
7mo ago
Mostly experience (based on being a PhD scientist, a postdoc, a National Lab scientist, and engineer at several bigtech companies), partly speculation (none of the groups/labs I worked in operated at "the highest level", but
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dekhn
7mo ago
Are you going to build a competitor to CERN? There are many things that cannot be feasibly verified empirically without access to rare resources.
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dekhn
7mo ago
Advanced groups usually replicate their competitor's results in their own hands shortly after publication (or they just trust their competitor's competence). But they don't spend any time publishing it unless they fail to re
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dekhn
7mo ago
Maybe nature and cell and a few other journals should be exceptions: they should be the place that the most advanced scientists publish interesting ideas early for the consumption by their competitors. At that level of science, all the com
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dekhn
7mo ago
The story has been updated with new data. It looks like (again, based on unofficial information sources) that the US military believes it made the mistake. https://www.nytimes.com/2026/03/11/us/politics&
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by
dekhn
7mo ago
I had a somewhat similar experience- was a postdoc for a pre-tenure professor at berkeley. after writing up a paper based on her methods, with poor results, I handed the draft to her. She rewrote it- basically adding carefully worded/
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by
dekhn
7mo ago
I wish he'd stop saying they solved the protein folding problem. They didn't. They made a step increase in the quality of protein structure prediction. That's a different (and simpler) problem. It's still a significa
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dekhn
8mo ago
It's a variation of nerd snipe. https://xkcd.com/356/ People get taken by the theoretical coolness and ultimate utility of the idea, and assume it's just a matter of clever ideas and engineering to make it a
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by
dekhn
8mo ago
I can't speak to the scientific conclusions in the article, but the smallest/simplest proteins go from completely unfolded to fully folded in a few microseconds. Other proteins will never reach their fully folded state without as
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dekhn
8mo ago
Oh god he saw through the fnords.
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dekhn
8mo ago
What's the plan in China for when one of these expedited treatments has a terrible side effect? The FDA's slowness is about maintaining a low level of risk because the reputation cost of a really bad incident is huge.
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dekhn
8mo ago
None of these machines actually do anything useful for protein folding or even static protein structure prediction. I have not seen any true examples of these computers generating approximate solutions for routing, scheduling or portfolio a
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dekhn
8mo ago
I'm pretty sure the parent post to mine was updated from "RAM" to "address space", although I'm not 100% sure.
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dekhn
8mo ago
mmap is a built-in module on python! Also true for perl.
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dekhn
8mo ago
Address space size and RAM are two different things.
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dekhn
8mo ago
See also: Spiegleman's Monster
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