cthalupa

33 ms·

571.
by cthalupa 2y ago
Lilly is probably in an even stronger position if retatrutide continues to look as good as it has in the current trials. Better weight loss than tirzepatide, and recent results have shown it has excellent results on reducing fat deposits in
572.
by cthalupa 2y ago
Risk factors for NAION are basically all the things that you go on these drugs to treat - type 2 diabetes, sleep apnea, cardiovascular disease, blood pressure, etc. One observational study that shows some correlation isn't enough for m
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by cthalupa 2y ago
> Drinking Being obese is probably worse for you. NAFLD has long eclipsed alcohol related liver issues. > Even simple unprotected sex can lead to massive medical problems Even treated HIV is probably less of a risk to your long term
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by cthalupa 2y ago
I’ll make my usual response: we know that being obese is basically the worst possible thing you can do to yourself, and the longer you are, the worse it is. The side effects are going to be pretty awful just to negate that, much less all th
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by cthalupa 2y ago
There are a lot of bodybuilders using it to assist with cuts, yes. They're largely focused on retatrutide at the moment, though, since it seems to be more effective and they're a group that already is comfortable injecting themsel
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by cthalupa 2y ago
One thing that I think is important to note is that a lot of people in this position aren't going to be wanting to become Runners with a capital R - they're going to be looking for the minimal effective dose to be healthy. Some, o
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by cthalupa 2y ago
Sure - you want to keep ramping up the intensity, otherwise yeah, you're not making any gains, be it in cardiovascular performance/VO2 max/max weight you can lift/number of reps you can do/etc. And yeah, I missed th
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by cthalupa 2y ago
You misunderstood my question. I'm pointing out that the compounding pharmacies and the med spas that buy from them are not getting it from any sort of official source - thus them getting sued. Having spoken to owners of compounding ph
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by cthalupa 2y ago
My understanding is that a significant number of them are getting them from Chinese manufacturers (that are also selling them to other Chinese companies, that then sell them to individuals, more resellers, or compounding pharmacies) I'
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by cthalupa 2y ago
Why are Eli Lilly and Novo Nordisk suing compounding pharmacies, then? https://www.reuters.com/business/healthcare-pharmaceuticals/... https://www.fiercepharma.com/pharma/lilly-files-complaint
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by cthalupa 2y ago
Most are newer, so the patents will expire later. Liraglutide is an older version that is now available as a generic, but it's results, particularly for weight loss, are far behind semaglutide, tirzepatide, etc.
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by cthalupa 2y ago
One interesting thing I have noticed on tirzepatide is I am much better able to differentiate when I am thirsty vs. when I am hungry. Before, if I wasn't getting to "my mouth is dry" levels of thirst, they were indistinguisha
583.
by cthalupa 2y ago
If by compounding you mean producing semaglutide, no. If you have a source to buy lyophilized semaglutide and some BAC water, you could certainly reconstitute it yourself and pick a dosage, or compound in some vitamin b12 or similar. In pra
584.
by cthalupa 2y ago
You can't exercise out of being fat. It's a hugely important thing to do for your health in general, but the amount of effort needed to counteract the modern diet via exercise is absurd. The alternative is eating better - better f
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by cthalupa 2y ago
> Not to mention that there are plenty of healthy overweight people This is only true in the most disingenuous of interpretations and look purely at BMI. The "health overweight" people are nearly exclusively those with signific
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by cthalupa 2y ago
It is significantly easier if you are starting from being totally sedentary. I've gone from fit and powerlifting for years to fat for years to trying to get back into lifting, etc. (the latter, multiple times) and while age is a bit of
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by cthalupa 2y ago
I find it significantly easier to eat healthier foods. I am struggling with getting enough calories in general - even on the lowest dose I have to force myself to eat more than a meal a day. But I don't miss the processed/fried&#x
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by cthalupa 2y ago
Not even particularly new. I remember seeing it used talking about Counter-Strike pros in the early 2000s
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by cthalupa 2y ago
There are some concerns with retatrutide - it's popular among the bolder people willing to buy it as a research chemical, and both their reports and the clinical trials do show significantly higher resting heart rates as a common side
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by cthalupa 2y ago
Your expectations are correct - there's a strong correlation between the two.
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by cthalupa 2y ago
What is your argument? That losing weight does not result in muscle volume loss? That GLP-1s are somehow special and only losing weight via them causes muscle loss? IFBB bodybuilders getting weekly DEXA scans and running multiple steroids i
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by cthalupa 2y ago
> To take the time to study the root causes of obesity more closely, and treat the genuine causes, instead of slapping medicine on top of it, for an undetermined period of time to millions of people. It's insane. What if medication
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by cthalupa 2y ago
> The immediacy of the danger makes things incomparable. Being obese is an immediate danger. It is an increase in risk for all cause mortality. Being obese today is making you more likely to develop cancer. It's making your more vul
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by cthalupa 2y ago
Note: I meant to type South Korea here, not North.
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by cthalupa 2y ago
Sorry - this was entirely due to me also talking politics with some friends earlier in the day. Switched up SK and NK when I typed this. Obesity in adult men in South Korea more than doubled between 09 and 19.
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by cthalupa 2y ago
You can make short cycles once or twice a year relatively safe for some steroids. Keep close track of your liver enzymes and blood pressure, discontinue if those look bad, otherwise stay on for 4-6 weeks, take half a year off, repeat. Got e
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by cthalupa 2y ago
If all it took to get the same feeling of GLP-1 agonists was success at the diet for 2-4 weeks, I would have a lot less experience being successful at diets for 2-4 weeks. A whole lot less.
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by cthalupa 2y ago
> I’m yet to see a person working out hard and eating at the same time. No, but plenty of people have their hunger stimulated by exercise and eat too much after. You simply can't fix being overweight or obese with exercise alone in
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by cthalupa 2y ago
> If educating people didn't work, we'd all be drinking cocaine soda and burning leaded fuel. When the person you are arguing with is saying that government induced bans would probably help more, and your are arguing they'
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by cthalupa 2y ago
Another option: Move to a healthcare system that allows the government to negotiate drug prices with pharmaceutical companies so ozempic is no longer so expensive that it bankrupts us. The UK gets their semaglutide meds from Novo Nordisk fo

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