ccooffee

20 ms·

151.
by ccooffee 4y ago
Finding an optimal donor match (via HLA typing) rarely returns many "perfect" matches. Perhaps there are systems that record both the CCR5 mutation and HLA typing, but I'd expect most donor matches, found via registries like
152.
by ccooffee 4y ago
"Last chance" describes both the way it was introduced to me by my medical team, and the circumstances around my SCT. I don't know how factually accurate it is, but my medical team had said there's about a 30% mortality
153.
by ccooffee 4y ago
From wiktionary[0]: > chapeau (interjection) - well done, a verbal representation of a hat tip Don't go to wikipedia[1], or else you'll be confused by "A chapeau is a flat-topped hat once worn by senior clerics." Than
154.
by ccooffee 4y ago
I've had an allogenic stem cell transplant. It was hell. I no longer have cancer, so it was worth it. But HIV/AIDS (with standard treatment and testing) no longer significantly reduces life expectancy. I have a hard time imagining
155.
by ccooffee 4y ago
Improving test environments is a huge upside. I haven't worked on browser automation in nearly a decade, but finding ways to work around shortcomings in the headless environment used to burn a lot of time on that team. I know of many s
156.
by ccooffee 4y ago
How do you say "CLI"? I've only ever heard it as "rhymes with fly", though maybe someone has spelled it out once or twice ("see ell eye").
157.
by ccooffee 4y ago
This is my experience as well. The higher-ups slap "privileged" on nearly all emails, even when they have nothing to do with soliciting legal advice (e.g. a company-wide email about internal policy changes). I wish I'd hear s
158.
by ccooffee 4y ago
"How to make great pancakes" sadly is not one of the anything to be learned. From poking around, this site seems to be a pointer-to-resources, rather than a road map of learning. While very useful, it seems like a tactical resourc
159.
by ccooffee 4y ago
Do you have a preferred source for this? I went down a rabbit-hole of googling and trying to evaluate how reliable the sources were and got pretty lost. I found several articles claiming to use data from the US Federal Reserve with conflict
160.
by ccooffee 4y ago
My iPhone 8 seems to work just fine for installing apps. I'm on iOS 15.6.1, though the [iOS 16 info page][1] claims support for iPhone 8. (I may have chosen not to upgrade to iOS 16 in the past because my 64gb phone is chronically low
161.
by ccooffee 4y ago
I don't know how well they work. I have a sibling with one that they use frequently, but that sibling is a bit odd. (I think the blanket circulates water through it, but I've never really asked.) Their use may just be due to a pla
162.
by ccooffee 4y ago
> even captain planet cartoon showed air conditioners being bad for the environment That seems like it was a useful simplification for a children's cartoon, but things aren't that black-and-white. 1. Without air conditioning (o
163.
by ccooffee 4y ago
Oh, neat! I was repeating a thing I'd heard, but is apparently misleading. According to a few sources I've found, paper is the name for anything primarily made of tangled cellulose fibers, which can be harvested from many differen
164.
by ccooffee 4y ago
This submission claims that "traditional banknotes which are based on special and expensive paper suffer from poor tear properties and they have limited life", and touts tallow-dependent plastics as a solution. US currency is made
165.
by ccooffee 4y ago
Personally, I found the "DIY" edition to be great. It was REALLY easy (probably took me 10 minutes, but could be done under 2 with practice), and by needing to "assemble" the product myself, I got much more comfortable o
166.
by ccooffee 4y ago
This reads like a hit-piece against ZipCar. The author doesn't give any advice, and merely retells a few anecdotes about people being stranded by parking a ZipCar in a place with poor cell service. This isn't a problem I'd th
167.
by ccooffee 4y ago
Sea level rise is the only one of those that has _thus far_ occurred. The others are projections for the future. In the case of sea level rise, the author would likely claim that human development patterns (e.g. paving everything for parkin
168.
by ccooffee 4y ago
I think the title of this article is a bit more inflammatory than most here, so it's likely to wake some of the trolls. That said, I think this is a well-written article which uses cited references to show: 1. Hurricanes have not becom
169.
by ccooffee 4y ago
Here's a story from Reddit about someone using these systems during over-the-board play to cheat: https://www.reddit.com/r/BestofRedditorUpdates/comments/xigy...
170.
by ccooffee 4y ago
Hadn't heard of this before. I found old copies of that newsletter on the internet at https://newsletterhunt.com/newsletters/money-stuff-by-matt-l... . (Relevant to this post, there was a post about Musk/Twit
171.
by ccooffee 4y ago
This is a great writeup, and reignites my interest in Java. (I've long considered "Java Concurrency in Practice" to be the _best_ Java book ever written.) I haven't been able to figure out how the "unmount" of
172.
by ccooffee 4y ago
Such a poor plan. Dropping this in a Q&A means that nothing else said will be remembered. It's also being implemented in a completely asinine way: "individual teams will sort out how to handle headcount changes". Take no
173.
by ccooffee 4y ago
I also saw this at a different SV company in 2015. Nothing new under the sun.
174.
by ccooffee 4y ago
I have NEVER heard of any of this. Can you provide any sources? I think the 5th has been restricted enough by the courts that it literally only matters if you EXPLICITLY invoke it. (At least this is my understanding of Berghuis v. Thompkins
175.
by ccooffee 4y ago
Redis is the only C or C++ project that I happily read the source to. Though I haven't done that since @antirez stepped back from the project. I imagine the code is still excellent...
176.
by ccooffee 4y ago
Is there a book you recommend for getting started with research? There is enough noise in this space that I find "search the internet" to be...difficult.
177.
by ccooffee 4y ago
The backing legislation, Health and Location Data Protection Act of 2022 (S.4408), was forwarded to subcommittee on June 15 but hasn't seen any action since [0]. That said, I don't know how quickly the Senate Committee on Commerce
178.
by ccooffee 4y ago
I wonder what would change in the criminal legal system if all warrant applications must be counter-argued by a public-defender-like-role. I suspect the "defender" would just end being an always-ignored voice in the room, at least
179.
by ccooffee 4y ago
I've lost many hours reading the pages in the "Hundred Rabbits" collection: https://100r.co/site/home.html (I'm fairly sure some of their links have been on HN before, perhaps the "working offg
180.
by ccooffee 4y ago
It looks like the article may have updated this sentence. It now reads as: > Mostly because people didn't believe that it was possible to exploit the retpoline limitations, it was somehow logical -but risky- to refuse to implement a

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