bionhoward

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by bionhoward 7y ago
Legit! We’re also working on the same exact type of CRISPR (Cas13) to treat/prevent CoV (as an extension of the Bit Pharma Bio Firewall project we’ve been thinking about for ~7years) here: https://github.com/bionicles&#
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by bionhoward 7y ago
causality, by judea pearl a pattern language, by christopher alexander maps of meaning, by jordan peterson on intelligence, by jeff hawkins the fractal geometry of nature, by benoit mandelbrot ^^^ a crash course in cognitive architecture fo
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by bionhoward 7y ago
My sales buddy played me this audiobook during a cross country road trip, it’s about the voice in your head, mostly the type of simple advice no one gives but it’s useful to hear spelled out explicitly, worth a listen The Power of Now by Ek
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Ethnic Bioweapon (Wikipedia)(en.wikipedia.org)
1 points by bionhoward 7y ago|0 comments
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by bionhoward 7y ago
Looks great until they hit the ELISA (antibody test) which requires pre-existing antibodies for the target. That’s like when you search for your keys under the streetlight when you dropped them in the dark. Anything novel becomes an expensi
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by bionhoward 7y ago
FOREIGN KEY (manager_id) REFERENCES employees (id) ON DELETE CASCADE sounds dangerous for job security
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by bionhoward 7y ago
This is cool because it can help quickly determine structures if the virus mutates. However, the obsession with structural biology isn’t necessarily optimal, because we’re talking about shapes of things (analog, constantly changing) instead
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by bionhoward 7y ago
Apple Watch is a joy to use. Helps you be more active, tracks your cardio, remote controls the TV, timers alarms flashlight messages EKG, I use it a ton and love it. Made under Tim Cook
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by bionhoward 7y ago
The biggest problem about cannabis re: covid19 is if you smoke it, it’s gonna impair the cilia which help clean out your lungs, also you’re putting your lips on some dirty piece (especially bad if shared between multiple people as one perso
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by bionhoward 7y ago
I’m not a doctor, but fusing a complement activator to a natural enzyme and megadosing it is a horrible idea because it’s gonna trigger complement activation in the context of a self protein, which could cause major autoimmunity, and ACE2 o
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by bionhoward 7y ago
Since protein folding is “solved,” you can make pathogen proteins with wildly different DNA to fool algorithms used to identify bioweapons. No bueno because baddies can order nasty germs printed cheap! There are no bug bounties for bio bugs
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by bionhoward 7y ago
you could add a new loop of DNA with a new gene, without an update to existing code. That might be easier than changing one letter Append only immutable biotech
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by bionhoward 7y ago
one way around this is to develop platforms which apply to a range of diseases. why reinvent some fancy shape of atoms for each disease? it's entirely possible to develop something which works on cancer and coronavirus. just look at CR
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by bionhoward 7y ago
source?
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by bionhoward 7y ago
We evaluated umpteen graph dbs this past year and chose vanilla Postgres instead because Neo4j/RedisGraph have insane licenses. It’s useful you’re comparing these languages. I would suggest to make yours more like Cypher, specifically
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by bionhoward 7y ago
Since when did the definition of a disease require the existence of a cure? This whole topic feels like semantic quibbling...we could spend more time designing anti-aging plasmids and less time debating which human sounds to use It doesn’t
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by bionhoward 7y ago
Aging is a disease because it is a “disorder [disruption] of structure or function in a human, animal, or plant, especially one that produces specific signs or symptoms or that affects a specific location and is not simply a direct result o
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by bionhoward 7y ago
you can download a bunch of sequences here (i filtered for lung and 'oronasopharynx'): https://www.ncbi.nlm.nih.gov/labs/virus/vssi/#/virus?SeqType...
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by bionhoward 7y ago
"But, as Deepak Chopra taught us, quantum physics means anything can happen at any time for no reason." - Professor Hubert Farnsworth
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by bionhoward 7y ago
The machines and reagents are super common. The critical missing element is the primer, a short sequence of nucleotides telling the PCR (gene copier) what sequence to copy Gene synthesis companies are probably ramping production of these pr
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by bionhoward 7y ago
is the loss you're talking about like fused gromov-wasserstein distance? we hit permutation invariance issues like what you're talking about in some atomistic simulations because the atoms need to be permutable if you want to use
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by bionhoward 7y ago
Kudos for infrastructure as code. Surprisingly many companies, particularly database companies, don’t deliver infrastructure as code yet, which makes it harder for their prospects to become paying customers. One way to make your examples be