4 ms·
Legit! We’re also working on the same exact type of CRISPR (Cas13) to treat/prevent CoV (as an extension of the Bit Pharma Bio Firewall project we’ve been think
by bionhoward 7y ago
Legit! We’re also working on the same exact type of CRISPR (Cas13) to treat/prevent CoV (as an extension of the Bit Pharma Bio Firewall project we’ve been thinking about for ~7years) here:
https://github.com/bionicles/coronavirus https://github.com/bionicles/coronavirus
Goal is to use gene therapy to make the lung cells delete the virus. Just imagine a Bio Firewall, that’s what we’re working on. We don’t modify the cells’ DNA, we add a new chromosome, and it’s possible to make that self-destructing, which we’ll do. got the side effect prediction algorithm working and posted a video on Twitter here: https://twitter.com/bitpharma/status/1240986466437791744?s=20 https://twitter.com/bitpharma/status/1240986466437791744?s=2...
Right now we’re expanding the side effect prediction index from lung CDS to the whole transcriptome with LevelDB ( multiple orders of magnitude more data but we can reuse this algorithm and the prebuilt index across a number of different CRISPR projects) you could use the same exact process for a number of bugs, Flu would be a good one!
Please hit me up at bion@bitpharma.com if interested to assist on stuff like plasmid design, computational directed evolution of stealth CRISPR, in vitro/vivo testing, or business stuff (we’re hackers not MBAs!)
/yolo