biomcgary

6 ms·

31.
by biomcgary 1y ago
I heard about big bounce/crunch models before, but thought they were discounted due to the acceleration of expansion, which suggests that gravity will not lead to a contraction. Does anyone understand how this new bounce model deals wi
32.
by biomcgary 1y ago
Cysteine plays a key role in redox metabolism and removing reactive oxygen species (ROS). During brown fat burning, high flux of electrons increases the NADH/NAD⁺ and FADH₂/FAD ratios — shifting redox state toward a more reduced e
33.
by biomcgary 1y ago
Sometimes (often?) technical legal definitions considered without context lead to absurd conclusions that don't manifest in practice. Does the FAA have jurisdiction over paper planes? What about the airspace in my house and does it mat
34.
by biomcgary 1y ago
Your genome only needs to store the information necessary for the lineage leading to you to survive and compete in the range of environmental variation that actually happened. Consequently, your DNA has less information about how to survive
35.
by biomcgary 1y ago
I was paid to get a PhD in Biology, albeit just enough to live on. Most people in PhD programs are, either through being a TA (teacher's assistant) or RA (research assistant). The real financial cost is the opportunity cost of 5-6 year
36.
by biomcgary 1y ago
Everything that reproduces is in an evolutionary arms race ( https://en.wikipedia.org/wiki/Evolutionary_arms_race ), so the "kicking the can" objection doesn't really make sense in this context. There is n
37.
by biomcgary 1y ago
An excellent description of a recent fundamental discovery. The post might have a bit more jargon than a non-biologist would immediately recognize, but it does convey the complexity and logic of both discovery and validation. As a computati
38.
by biomcgary 1y ago
Should be 1-trit.
39.
by biomcgary 1y ago
Yes, one would expect kin / group selection to play a role.
40.
by biomcgary 2y ago
In the end, I suspect most cults want all your organs.
41.
by biomcgary 2y ago
Marcus Aurelius was the last of the Five Good Emperors because he did not adopt a competent, non-biological son to take his place like the previous four. Instead, he set up Commodus as Caesar and his heir, despite his mental instability. Th
42.
Show HN: Fast Transition from Firefox to Librewolf
78 points by biomcgary 2y ago|49 comments
43.
by biomcgary 2y ago
Washington's opinion might well have changed and, as noted in other comments, an armada of nuclear ICBMs does negate the distance that he referenced. Regardless of the hypothetical, isn't it clear that Trump IS meddling and not fo
44.
by biomcgary 2y ago
George Washington's farewell address (1796) - on Europe: The great rule of conduct for us in regard to foreign nations is in extending our commercial relations, to have with them as little political connection as possible. So far as we
45.
by biomcgary 2y ago
My house has a super-insulated, passive solar design. I heat it with wood pellet stove, which requires electric power to run the fans and pellet feed system. I've often wanted to add a Stirling engine and a small battery to make it tru
46.
by biomcgary 2y ago
Currently, I'm using generative AI of various kinds on my M1 Air (llm, image gen, TTS, STT), but am frustrated by the limitations - primarily memory and secondarily availability of an MLX adaptation. Just an AI hobbyist, so I don'
47.
by biomcgary 2y ago
The 8 cycles between boiling and room temp would be tedious without automation. I wonder if a similar outcome would be achieved by sous vide followed by boiling briefly to set the white, much like sous vide steak followed by searing.
48.
by biomcgary 2y ago
A Christian recommending a serpent-named language to get closer to God is pretty entertaining. What about Go "and make disciples"?
49.
by biomcgary 2y ago
Is diverging harder? I find it easier. Maybe it is from long ago practice on stereograms, but I'm curious if it could be due to neurological/physiological differences.
50.
by biomcgary 2y ago
Agglomerative clustering
51.
by biomcgary 2y ago
I think owner-operated mother-in-law suites and similar allow neighborhoods to strike a nice balance between long-term community commitment and supporting reasonable amounts of of tourism. My wife and I host an Airbnb just outside the city
52.
by biomcgary 2y ago
Evidently someone is a fan of Big Hero 6.
53.
by biomcgary 2y ago
I've followed GNNs in biology and applied them in a couple domains, but have been disappointed by the results so far. I'm a bit surprised because I have successfully used other graph-based approaches in biology.
54.
by biomcgary 2y ago
https://en.wikipedia.org/wiki/Tacit_knowledge
55.
by biomcgary 2y ago
On the last level I ran into one of the raised blocks and tunneled into the cubes. I could still roll around inside, lol, but there was no way out.
56.
by biomcgary 2y ago
So many assumptions are necessary for this type of research, particularly for the timing. Inferring such an early age depends on a "clock" that varies based on the stringency of purifying selection. I.e., it is only clock-like to
57.
by biomcgary 2y ago
Natural selection encodes adaptive responses to the environment in DNA (and other molecules), so memories can be encoded to the extent that they are adaptive and can be encoded (i.e., mechanisms may not exist to encode everything using only
58.
by biomcgary 2y ago
Am I correct to assume people are upvoting this as a possible explanation for the outcome of the US Presidential election? I.e., if people think that they are in economic doldrums or decline, taking a risk seems better than the status quo?
59.
by biomcgary 2y ago
Glad she recovered!
60.
by biomcgary 2y ago
We know there are lots of biological mechanisms that retain state at the cellular level to put it in CS-ish terms. A fraction of these mechanisms could plausibly be transmitted outside the cell (e.g., miRNA). These mechanisms may or may n

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