bglazer

17 ms·

211.
by bglazer 3y ago
Having worked at FedEx, I can say that there’s actually a decent amount of interesting work to be done. First, the website gets a ton of traffic. Granted, it’s not google scale but it’s still significant enough to be interesting. The more i
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by bglazer 3y ago
Personally, if there was an easily verifiable, continuous example of a phenomena that violated basic physics and it was arranged in such a way that it sent a clear message confirming the existence of a deity, then I’m easily done with athei
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by bglazer 3y ago
This is very well written and the last paragraph really drives home what a disaster this is
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by bglazer 3y ago
Sure, let’s lower everyone’s standards of living - except for the richest people who won’t change their behavior at all. That’s so politically toxic that its effectively a fantasy. That’s the problem with these tax and prices based economic
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by bglazer 3y ago
One aspect of archaeology that I really find fascinating is the practice of leaving certain artifacts unexplored. The original discoverers of the scrolls tried to unroll a few, apparently found it was impossible without completely destroyin
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by bglazer 3y ago
Probably not, DNA degrades relatively quickly in uncontrolled conditions, so the unique markers of an individual human would probably be hard to grab from a dust particle suspended on a spider web. This works for detecting different species
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by bglazer 3y ago
This is deeply stupid on its own merits and reveals a complete inhumanity in Hotz’s core beliefs. Not worth talking about beyond that
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by bglazer 3y ago
Can you provide a source? That sounds unlikely
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by bglazer 3y ago
When you show images of a spider to a six month old baby their pupils expand, which is apparently a pretty reliable physiological indicator of fear. https://www.cbs.mpg.de/Fear-of-spiders-and-snakes-is-deeply-...
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by bglazer 3y ago
My understanding is that this is mainly affecting publishers that are widely known to publish low quality, mostly forgettable research. Like there’s thousands of “machine learning” papers published in MDPI and Hindawi journals that are lit
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by bglazer 3y ago
Definitely a treatment. MYC is only a problem once cancer finds a way to generate too much MYC protein. Only them is it necessary for a drug to knock it back down
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by bglazer 3y ago
It’s not terribly hyperbolic. The headline is that they tamed the protein (MYC). That’s more or less true, they found a molecule that binds to and blocks MYC’s activity. Then in the article they (correctly) note that MYC is dysregulated in
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by bglazer 3y ago
Here’s a peer reviewed study that directly compared semaglutide to placebo with additional lifestyle change support. Semaglutide just worked way, way better. https://www.nejm.org/doi/full/10.1056/NEJMoa2032183
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by bglazer 3y ago
They use a master equation for transcription, so they could theoretically get bursty behavior. But, my understanding is that the most well understood cause of burstiness is caused in eukaryotic cells by rearrangement of histones allowing tr
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by bglazer 3y ago
> Feels like there’s an ossification of this entire sector that happened years ago and there’s no sense of urgency Ok, can you explain what you meant by this?
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by bglazer 3y ago
Antibody drug conjugates are one attempt at doing this. Basically attach chemotherapy drugs to molecules (antibodies) that bind only to proteins on cancer cells
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by bglazer 3y ago
There are a ton of challenges to better oncology treatments. First, as many have noted, cancer is a constellation of diseases. Often a single tumor will contain multiple different, but related groups of cells. So most treatments will only w
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by bglazer 3y ago
So you just take for granted that cultural exchange is a net negative? Why do you think people won’t learn anything useful from another culture? Since you insist, I can provide a personal example. My former boss is from Colombia. I’m from t
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by bglazer 3y ago
It’s worth noting that tobacco consumption has decreased in many places, especially high income countries, but it’s increasing in many countries
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by bglazer 3y ago
Edit, sorry i think I misunderstood your post. Are you asking about how a hypothetical non-Chinese person would improve an all Chinese team? If so, I don’t presume to know. That would be up to the team members to find the ideas that best he
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by bglazer 3y ago
I’m not interested in doing a rank ordering of racial groups. You're setting up a false dichotomy: people are the same and diversity is neutral or some people are better and diversity is bad. You seem to be assuming that its perfectly
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by bglazer 3y ago
I don’t assume a link between groups and ideas. Its something many people have observed. This is typically called “culture”. The thing about people and cultures is that they are comprised of many different, often changing, sometimes mutuall
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by bglazer 3y ago
My understanding is that diversity statements are typically asking what you plan to do build/maintain diversity. Like, “I’ll start a science club at a local elementary school with a large population of underrepresented students”. It’s
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by bglazer 3y ago
No, you’re wrong. Belief in “diversity” is the belief that many different groups/identities can contribute, and that none are strictly “best”. DEI is an effort to include more groups in institutions, in order to benefit from the mixing
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by bglazer 3y ago
Yeah, the article really places the blame squarely on individual bad choices due to declining mental health from covid and other bad news things. I find it plainly absurd that thousands of additional car wrecks are due to people feeling sad
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by bglazer 3y ago
Fuck that’s crazy. For the CS people who don’t understand what this means, a rough analogy is that HIV does something like steganography to encode two proteins in one gene.
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by bglazer 3y ago
Yep these operations are going to be disasters. Huge plumes of waste silt, noise pollution, and permanent destruction of ecosystems whose role were don’t understand.
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by bglazer 3y ago
Can you be more specific about which subcultures have ingrained criminality? It's better to have the courage of your convictions and just state outright which groups of people have a criminal nature.
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by bglazer 3y ago
I don’t think it would make terribly compelling children’s television to just show the children misbehaving and the dad disciplining them.
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Autonomous, multiproperty-driven molecular discovery(science.org)
2 points by bglazer 3y ago|0 comments

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