alexholehouse

11 ms·

31.
by alexholehouse 11y ago
The CJD controls had sporadic (sCJD), not variant CJD (vCJD) (whether or not these are distinct diseases is certainly an open question - I'm more trying to make the point that there are a lot of variables up in the air, and while it&#x
32.
by alexholehouse 11y ago
Both this result and the preceding paper are also entirely consistent with the hypotheses that: 1) People who are susceptible to vCJD are more susceptible to AD 2) The (cellular) stress caused by vCJD increases susceptibility for AD 3) Peop
33.
by alexholehouse 11y ago
This is very nicely writen, and looks like an extremely useful resource for those interested in entering the bioscience field. I would offer one word of caution, which I think is especially pertinent to those coming from a CS background (an
34.
by alexholehouse 11y ago
From a cursory reading of the article this looks like it's solving an extremely similar problem to Gaussian Process Bayesian Optimization (GBPO [1]) in a fairly similar way. I wonder what a head-to-head comparison between these two wou
35.
by alexholehouse 11y ago
I should (sheepishly) say that I knew Vol. 1 and 2 were available but very recently discovered 3 was now also available. As it turns out, 3 was published a while ago, so while it was new to me, the full set being available was not, in fact,
36.
The Feynman Lectures on Physics are free online(feynmanlectures.caltech.edu)
247 points by alexholehouse 11y ago|20 comments
37.
by alexholehouse 11y ago
Does that mean a lack of funding can't catalyze the issue? Edit: Just for transparency (topical!) I did not downvote you, and totally agree that cronyism is a major (and yeah maybe causative) issue, but I also think the decision on
38.
by alexholehouse 11y ago
Posts like this (and there are many of them) scare me. I'm in the latter half of a PhD. I love it. I work insane hours entirely out of my own choice, because it is the most rewarding and enjoyable thing I've ever been a part of. T
39.
by alexholehouse 11y ago
So the idea that neurodegeneration is essential a manifestation of protein-specific prion disease is not a new idea[1][2][3][4][5] but is one which is steadily gaining traction. That said, from a complexity perspective we're still at t
40.
A Neural Algorithm of Artistic Style [pdf](arxiv.org)
56 points by alexholehouse 11y ago|6 comments
41.
by alexholehouse 11y ago
I'm currently building a 2D/3D simulation engine as part of my PhD - it's uncanny how incredibly simple physical principles generated output that has the "look 'n feel" of organic phenomena.
42.
by alexholehouse 11y ago
Related discussion from a few weeks ago; https://news.ycombinator.com/item?id=9895094
43.
by alexholehouse 11y ago
http://www.reddit.com/r/Bitcoin/comments/3fe92x/im_ashley_ba...
44.
by alexholehouse 11y ago
I don't understand; 1) What's the 'top words' which appears when you search for a site? I just get a bunch of profanities (for basically any show, even those which are PG-13). Is this meant to be the top words found in t
45.
by alexholehouse 11y ago
One angle not touched on here is the link between Alzheimer's disease (AD) and sleep. There has always been evidence that AD patients sleep less than the general population, but obviously there's a chicken and egg problem here -
46.
Live Coverage of New Horizons' Pluto Flyby on Tuesday (Jul 14th)(nature.com)
6 points by alexholehouse 11y ago|0 comments
47.
by alexholehouse 11y ago
Technical question - I've seen reports that, "...people who have installed the game to SSD's are apparently getting better performance" [1]. Which implies, to me (both intuitively and having worked on a lot of high perfo
48.
by alexholehouse 11y ago
This is such a morbid topic that I've never acted on it, but I suspect that with historical news data you could figure out the growth rate laws which relate time since disaster occurred with number of reported casualties to build a pre
49.
by alexholehouse 12y ago
In the biomedical community the standard way to interact with VMD[0] - one of the major molecular viewers and really a workhorse of modern biology - is through Tcl. I always think this is rather unfortunate, because it means that for many p
50.
by alexholehouse 12y ago
Sadly, I think this is perhaps the only (?) reason to stay in academia any more (albeit a very good one).
51.
by alexholehouse 12y ago
> explaining that such masses were common among women, and suggested Scott have it checked again in a year. I know this sounds insane, but menigiomas (which I'd guess is what the neurologist suspected it was) are almost always benig
52.
by alexholehouse 12y ago
Wait what? They built an 'iOS based operating system'? I don't understand how that would be possible?
53.
by alexholehouse 12y ago
Then those people have no business filing software-related trademarks.
54.
Authors publish failure to replicate own work (PLOS Neuroscience)(neuro.plos.org)
2 points by alexholehouse 12y ago|0 comments
55.
by alexholehouse 12y ago
Please someone correct me, but assuming you didn't sign anything, I suspect your recourse beyond "AGRGRGRHRGRHGRGHRHGRRHGR" is limited (not that this posts suggests you're looking for vengeance or anything). That really
56.
by alexholehouse 12y ago
Original article http://link.springer.com/article/10.1007%2Fs11481-014-9552-2 (paywalled)
57.
by alexholehouse 12y ago
As someone who works in dementia research (...), I can't help but notice the total absence of any well defined target for the challenge, which makes it, for a goal-oriented objective process, a poor choice. "If Dementia wins the
58.
by alexholehouse 12y ago
Or in the shower (or, as I like to call it, "The idea chamber").
59.
by alexholehouse 13y ago
This is probably one of my favourite HN posts of 2014. Outstanding.
60.
by alexholehouse 13y ago
THIS. One hundred times this. For these results to be in any way meaningful you need to conduct the experiment three times (and, three times with one person isn't actually enough to actually pull statistically meanigful results from, b

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