ak217

49 ms·

541.
by ak217 7y ago
There are many RT-PCR LDTs. It does not take very much to create a real-time RT-PCR LDT for COVID-19; two weeks ago the CDC posted a comprehensive description of the process on their website, but it was not a secret before then. All you nee
542.
by ak217 7y ago
AWS refunds you when that happens. The fundamental issue with setting a limit is it's technically infeasible to decide what to do when it's exceeded. They have no way of knowing what assets to terminate. The way to avoid what you
543.
by ak217 7y ago
Both AWS and Google offer free tier products and pay-for-what-you-use products. Reserved instance pricing starts at around $25/year. Many other incredibly useful products (S3, Lambda, VPC, etc.) are free with an instance or start at $0
544.
by ak217 7y ago
AWS pricing changes over time (although they are careful not to trap or antagonize customers with changes like this one). You linked to a static blog post that has a price from the past. https://aws.amazon.com/eks/prici
545.
by ak217 7y ago
I agree with you on the advantages of U2F/WebAuthn, but the rest of your comment seems pretty oblivious to the usability challenges of TOTP MFA. The security risks that you cite are remote and orthogonal to the security risks of not ha
546.
by ak217 7y ago
"The jury is still out"? On what, the Rotary club? Your underlying assumption that churches are unique as providers of social capital in modern society is... peculiar. The fact that churches are tax-exempt is a consequence of the
547.
by ak217 7y ago
At a previous job, I deployed btrfs to production in a system that continuously spins up and shuts down thousands of VMs. A key feature that I was able to leverage to make this easy is seed devices. This btrfs feature works similarly to ove
548.
by ak217 7y ago
I can recommend the Thinkpad Thunderbolt 3 dock. It's fully compatible with the MacBook Pro. With the latest firmare (or gen2 of the dock - there are two generations), it supports MBP with 2x4K@60Hz (on gen1, one of them needs to be dr
549.
by ak217 7y ago
Last time I checked, Microsoft had nothing like the Sheets API. However, since then, as the sister comment points out, they have published the Graph API ( https://docs.microsoft.com/en-us/graph/api/overview?toc
550.
by ak217 7y ago
I think the actual pain in Python 2 came from the misguided decision not to adopt UTF-8 as the default character encoding, combined with silent coercion between unicode/bytes whenever needed. Those two features in combination made Pyth
551.
by ak217 7y ago
These summaries are known to academics as review articles. For some examples of great review articles, see the Nature Reviews journals.
552.
by ak217 7y ago
In the rest of the universe, going to the beginning/end of the line is mapped to the Home/End keys (fn+left/fn+right on Macs), and I do prefer it when my thing does things in ways that roughly correspond to how the rest of th
553.
by ak217 7y ago
This is a great, highly accessible guide. The biggest value add is in the description of the protocol, although the W3C standard ( https://www.w3.org/TR/webauthn/ ) was also expertly written and is a great, relative
554.
by ak217 7y ago
That's not true. Under London Breed, San Francisco has accelerated the rollout of safe bike lanes using the "quick build" program ( https://www.sfmta.com/vision-zero-quick-build-projects ). Ask any cyclist in S
555.
by ak217 7y ago
Several of the warts in Terraform were fixed in 0.12. While I think the HCL DSL was a mistake and prefer the CloudFormation YAML, CloudFormation has its share of warts as well, and the TF community has been doing better than CF in staying u
556.
by ak217 7y ago
I have developed something similar on top of the AWS CLI that incorporates a bunch of integrations with other tools like the cloudinit and various bits of Batch-related instrumentation: https://github.com/kislyuk/aegea
557.
by ak217 7y ago
- The others are trying to tell you, in good faith, why they think such a move would be politically intractable. Grandstanding rhetoric doesn't help your argument. - Not requiring your parents to be rich is otherwise known as intergene
558.
by ak217 7y ago
Sorry if I wasn't clear. I agree with you that local-only solutions are needed. Home Assistant is sucking up too much of the air in the room. I don't think it will ever be accessible or usable to the general population. If not for
559.
by ak217 7y ago
I think people who expect Home Assistant to be useful to the general consumer are delusional. Home Assistant is an amateur piece of software with severe UX shortcomings and broken auto-update functionality (it phones home continuously and o
560.
by ak217 7y ago
The original point of yours that I find issue with was about "perhaps why most scientists are less concerned", which is really bullshit because most scientists in the field are concerned about premature germline editing. And the
561.
by ak217 7y ago
The concerns about the LHC were a hell of a lot more hypothetical than about germline editing, and that did change the calculus. We know that current genome editing techniques have off-target effects. You're arguing from some abstr
562.
by ak217 7y ago
Yes, and many more cause carrier mutations that won't surface until the next generation, or late-onset metabolic or neural disorders that will cripple the individual later in life, or increase mutational load resulting in much higher c
563.
by ak217 7y ago
I don't follow. Gametes are isolated from many viral infections, but even assuming that a gamete undergoes viral mutagenesis, that's not evolutionarily novel (viruses follow relatively predictable insertion patterns, and transpo
564.
by ak217 7y ago
There's a huge difference between somatic and germline editing. Surgery is like somatic editing. It's elective, based on medical need, and its effects are confined to one individual. Germline editing is more like forcing an entire
565.
by ak217 7y ago
I plan to read it at some point, but I was really turned off by Stoller's relentlessly cloying self-promotion in his newsletter. I get it, he writes well on important topics, but he could use a bit more subtlety in pushing his stuff.
566.
by ak217 7y ago
Sure - on AWS, it's the 3 year reserved term for a t3.nano ($51 for 3 years or $27 for 1 year for 512 MB RAM and burstable CPU as described here: https://docs.aws.amazon.com/AWSEC2/latest/UserGuide/bursta
567.
by ak217 7y ago
$300 a year is nothing compared to colocating your own server, or even getting a business-grade network connection. If you can get away with hosting on your own computer on a residential connection, that's great for you, but it's
568.
by ak217 7y ago
After paying to colocate an old rack server and paying exorbitant amounts as a student, I now enjoy using pay-for-what-you-use AWS and GCP services. A colo box can be great if you can amortize the cost among a dozen friends. Otherwise, I th
569.
by ak217 7y ago
Thanks, this is a nice introduction. Two typos in this sentence: One way to work around this problem is to use a non uniform spaceing of the pulses which is none as staggering. (spacing, known)
570.
by ak217 7y ago
It's extractive to the extent the economy at large is extractive. Your index fund invests indiscriminately in profit-seeking enterprises proportionately to their size. A lot of profit-making economic activity is dependent on things lik

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