Yes, and many more cause carrier mutations that won't surface until the next generation, or late-onset metabolic or neural disorders that will cripple the indiv

Yes, and many more cause carrier mutations that won't surface until the next generation, or late-onset metabolic or neural disorders that will cripple the individual later in life, or increase mutational load resulting in much higher chance of cancer. The fact that some mutations are benign and others fatal really doesn't change the issue that we don't yet know how to safely edit the human germline.