LarsDu88

40 ms·

811.
by LarsDu88 2y ago
Time for an OpenFold3? Or would it be an OpenFold2?
812.
by LarsDu88 2y ago
As a software engineer, I kind of feel uncomfortable about this new model. It outperforms Alphafold 2 at ligand binding, but Alphafold 2 also had some more hardcoded and interpretable structural reasoning baked into the model architecture.
813.
by LarsDu88 3y ago
Just remember that the previous 15 years were a historically unprecedented low interest rate environment. We also have AI based efficiency boosting tools and greater offshoring to contend with
814.
by LarsDu88 3y ago
I've done hobby gamedev in Bevy/Rust, Godot/C#, and Unity C#. It's honestly somewhat baffling to me that folks will choose Rust for gamedev right now. The state of the open sourced tools are just not there yet, especiall
815.
by LarsDu88 3y ago
Fool me once shame on me. Fool me twice...
816.
by LarsDu88 3y ago
Great writing. Great voice acting. Why the hell are all the non-pivotal scenes barely animated? Like in one episode an alien spaceship blows up and a static gif of an alien goes spinning around. Just compare that to the animation in Xmen &#
817.
by LarsDu88 3y ago
When I saw the title, I immediately thought of the show "Invincible" which had abysmal animation, and lo and behold, its right there are the top of the list.
818.
by LarsDu88 3y ago
This is seriously the most impressive visualization I've ever seen. What tool did the author use to do this?
819.
by LarsDu88 3y ago
I became a dad this year, and I've long been thinking that the perfect LLM startup idea really could be centered around collecting data as an insurance policy against dying. Justin Kan strapped a camera to himself over 20 years ago rec
820.
by LarsDu88 3y ago
It's silly to post a headline of a large operating loss when the unit was literally partitioned off a few months ago. Building fabs is expensive... literally the most cost intensive manufacturing enterprise in the world. Making those i
821.
by LarsDu88 3y ago
Intel's ARC chips are actually pretty good, and would be pretty competitive with NVIDIA for the gaming market if not for the drivers... NVIDIA has three decades of DirectX driver support for many, many old games. Intel's ARC GPUS
822.
by LarsDu88 3y ago
Intel Foundries don't make ARC chips. Those are made by TSMC
823.
by LarsDu88 3y ago
I remember being super hyped for the successor of the floppy disk back as a kid in the 90s... Iomega Zip Drives. And then getting super hyped for the successor to the CD... the BluRay, and wondering what sort of holographic multi terabyte w
824.
by LarsDu88 3y ago
My experience has been... if you are competent enough to write a good prompt, you were probably good enough to write the code to being with. LLM copilots simply make that writing faster by 1.5x to 2x
825.
by LarsDu88 3y ago
It's mechanically simpler until the apex seals blow out. Then you are fucked
826.
by LarsDu88 3y ago
Interesting. I think TLR-9 stands for toll-like receptor 9. And these toll proteins were originally studied in fruit fly dorsal ventral patterning and also play a role in the innate immune system which we share with insects. If this study i
827.
by LarsDu88 3y ago
Yep. In nature, the "writing" aspect is actually writing down a chunk of the virus's sequence to know what to attack in the future. It's a little 'ol immune system for yogurt bacteria!
828.
by LarsDu88 3y ago
There's just one more evolution jump to get rampant mammal to mammal transmission
829.
by LarsDu88 3y ago
You never retract the landing gear on the shakedown flight. I remember seeing this watching a documentary on the X-35 and X-32 prototype fighter jets.
830.
by LarsDu88 3y ago
Windmills have giant turbines eh? Wouldn't it be easier to just invent an IKEA windmill blade than an entire frickin airplane?
831.
by LarsDu88 3y ago
Jet engines are a "solved problem" like "moon landing" is a "solved problem"
832.
by LarsDu88 3y ago
Hmmm. Augmented reality display, Carbon fiber frame, supersonic intakes... And 3 J85-15 jet engines designed in the 1950s (?) I remember reading about these J85 engines in an issue of Popular Mechanics roughly 20 years ago. This engine was
833.
by LarsDu88 3y ago
I studied it very closely to try to comprehend how someone could create something like that so quickly. The difference between Notch's LDJAM projects and other folks is that HE WROTE THE ENTIRE FUCKING ENGINE ALONG WITH THE GAME. Sprit
834.
by LarsDu88 3y ago
Folks underestimate how incredibly skilled Notch was and is. Unfortunately ludum dare has taken down its historical compo pages, but I remember that he had several games built from scratch in 24 hours which were mind boggling impressive. On
835.
by LarsDu88 3y ago
Parents who started companies. Lookin' at you Walton kids!
836.
by LarsDu88 3y ago
Love where Bevy is going. On the UI/UX side it has a long way to go, but on the non-rendering backend architecture side it can beat Unity, Unreal, and Godot in the long run. Just crossing my fingers because by the time Bevy reaches tha
837.
by LarsDu88 3y ago
I remember reading about the Lycurgus cup ( https://en.wikipedia.org/wiki/Lycurgus_Cup ) years ago in college. Pretty cool we can now control the phenomena. Highly, highly doubt this will result in a commercial competito
838.
by LarsDu88 3y ago
Man it really HAS been 20 years since the DARPA challenge. I am OLD
839.
by LarsDu88 3y ago
Jedi Knight 2 came out in 2002 and the original Call of Duty came out in 2003, both running heavily modified versions of John Carmack's Quake III engine
840.
by LarsDu88 3y ago
Wow they built a whole game engine and editor just for this game, and they got David Duchovny and Marilyn Manson to voice act in it! And now it lives in obscurity

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