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Amygaz
searching PlanetScale…
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241.
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Amygaz
9y ago
Well, if no thanks then, I am glad you have this hobby and I am glad you posted this, at a very timely moment of the year, which coincides with me needing to burn some extra vacation days (because nothing is created, nothing is lost, except
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Amygaz
9y ago
And you can his recent $700 billions in extra spending to DOD, which isn't part of the budget.
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Amygaz
9y ago
Well, only if someone in his entourage wants to do something about pollution and climate change. And then he will propose $50 millions to do it, while investing billions on other things that pollute and accelerate climate change... Otherwis
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Amygaz
9y ago
We are not in the same historical conditions. We have internet, darknet, social media, citizen journalists, cloud distribution... So maybe we don't need the traditional system. Maybe we need more people standing up against injustices,
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Amygaz
9y ago
Well that CEO transitions makes it clear that this isn't about developing a product anymore, but selling a brand. That new CEO is not going to develop and long lasting company, he is going for the sale. And the timing is good.
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Amygaz
9y ago
While I agree with you, I want to point that last October Health Canada decided that soylent could not be sold in Canada anymore, because it doesn't meet the minimum requirement of a meal replacement.
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Amygaz
9y ago
That was also my impression. It's kind of ironic that a Data Science/Strategist writing would be so heavily opinionated and have so little in term of data.
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Amygaz
9y ago
Yes, Northeast side, like Wedgwood to Lake City.
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Amygaz
9y ago
I liked the 1st part of the book, the point that making something happens is more valuable to society than incremental update. To me that's the only definition of innovation and disruption. However, the rest is where is narcissism shin
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Amygaz
9y ago
I doubt it is one those two things. You need to think of the overall personality, all the small and big things, the ideology, the narcissism... these add up, and overtime one just get fed up. I am not connected to YC, but when I read that t
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Amygaz
9y ago
Pretty sure that specific place wouldn't have care how eastern she had been, if she had had 'Harvard' written somewhere. They most likely had someone else in mind and were just wasting your wife's time.
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Amygaz
9y ago
In the bad news section, there is gentrification in many neighborhood where lower class and middle class single-family houses are being destroyed to build larger single-family upper-class... Because, you know, a family of 4 needs 5000 sqft
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Amygaz
9y ago
Then closely followed by the spreadsheet.
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Amygaz
9y ago
Probably why there are so few good CEO
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Amygaz
9y ago
And modern requirement for additional administrative roles and salaries, both directly and indirectly linked to that business, have probably more to do with inflation...
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Amygaz
9y ago
I feel like this thread is ignoring the main point, which is that preventative maintenance would have been cheaper. Also, when this thing started falling, they could have stopped it earlier, which would have resulted in cheaper repair, but
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Amygaz
9y ago
Basically, you're going to engineer new insects... I love it! I'm in! Can't wait to see the big chemical companies' faces when they see a poster on new breeds resistant to everything they have on the market or contemplat
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Amygaz
9y ago
Overall I would take that study very lightly. They basically took a cohort of student that did not have to read anything meaningful until then. In highschool they may have had some text and some work to do on a laptop, but the bulk of it wa
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Amygaz
9y ago
It's mostly about clicks now! If they think your story or your PI's name will drive traffic then it gets accepted. There are still a few very well done top notch paper that gets there, and some other half-backed but very creative
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Amygaz
9y ago
If you call your bank they will ask you for your account number (found on the check), Name (on the check), Address (on the check) and date of birth (not on the check), information about recurring deposit or last deposit (not on the check),
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Amygaz
9y ago
While waiting for a better network in every part of globe, we do need local power like you described. But, none of your examples couldn't be implemented remotely, and be more powerful if implemented remotely. We have all the tech to ha
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Amygaz
9y ago
Are tomatoes grown in the UK more tasty, or is it all the same? I am asking because I've moved back/forth a couple time between the US and Canada, and tomatoes made in the USA or central/south America are tasteless in the US.
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Amygaz
9y ago
Assholes don't write a 10-pages letter to help you do your job. They especially do not help you do your job. Scott is unlikely to be an asshole. His, was a friendly comment. From what the author wrote, the comments allowed him to ponde
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Amygaz
9y ago
My impression is that this is mostly a publicity feature for the book and the author than anything else...
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Amygaz
9y ago
It's "funny" how they take all their high quality enzymatic reagents from the company NEB and do this error-repair step (which something NEB has claimed and shown that people should be doing with their NGS sample), and whole
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Amygaz
9y ago
You know me? I'am considering taking CS as a part-time education, but I have no intention of becoming a software engineer.
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Amygaz
9y ago
Mosaicism is not inherently bad. It is definitely case specific. The current technology just doesn't allow much control over how much mosaicism you will get, on top of the off-targets, which is your point basically. The same mosaicism
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Amygaz
9y ago
I just want to buffer a little bit what you said about "the p-value is just checking a box more than being used as a tool for discovery.", but we are likely on the same page. Sometimes, it is necessary to use a significance test i
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Amygaz
9y ago
Maybe because chemo currently gives you 10% chance, while gene editing at the whole embryo level has 100% chance of resulting in mosaicism. This more recent work by Mitalipov's group dealt with single cell embryo and still ended up wit
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Amygaz
9y ago
If Amazon didn't host Netflix, Netflix would have been hosted on a competitor's platform. Nothing would have changed about Netflix and Amazon, plus many others, competing in the production and delivery of entertainment content.
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