7 ms·

'Gwada negative': French scientists find new blood type in woman

184 points by spidersouris 1y ago

deleted 1y ago
[deleted]
kalium-xyz 1y ago
This is one of those things that doesnt matter most of the time but when it matters it really matters.
xyst 1y ago
It’s cool to see these discoveries, but as a patient. It’s probably a nightmare to be unique in this aspect. If American, think higher costs of care. If involved in car accident or other traumatic injury outside of normal area, good luck getting your blood transfused. Might get lucky with substitute. Surgery preparation also more complicated. Maybe you have competent medical staff that recognize it. Maybe a few hematologists in the world familiar with your blood and history. Maybe a few neurons fire off in the back of an aging emergency physician that recalls this in a case study he/she read about in medical school/residency.
escapecharacter 1y ago
Manga lore fan wikis about to go nuts...
- PokemonNoGo 1y ago
  Why?
  - muzani 1y ago
    Japanese culture looks at blood type as indicative of personality, like horoscopes.
waltercool 1y ago
[dead]
tetris11 1y ago
I wonder why they named it PIGZ
ajb 1y ago
The OP is low on details. There is more in this article (in french): https://www.lindependant.fr/2025/06/21/il-ny-a-quelle-qui-est-compatible-avec-elle-meme-aujourdhui-dans-le-monde-un-nouveau-groupe-sanguin-decouvert-chez-une-francaise-12776910.php https://www.lindependant.fr/2025/06/21/il-ny-a-quelle-qui-es... Apparently the ISBT have added this to their list: https://www.isbtweb.org/isbt-working-parties/rcibgt.html https://www.isbtweb.org/isbt-working-parties/rcibgt.html (the page still says 47 but the data tables have it added)
- xattt 1y ago
  Neither article talks about whether this is a minor or a major antigen. Blood for transfusion needs to be crossmatched against antigen types of the recipient. Many patients will tolerate several transfusions of a minor mismatched antigen before developing a sensitivity. Major antigens are what cause significant reactions that can be life-threatening. Minor antigens come into play when crossmatching for infants and premies, but this is way beyond my scope.
  - mmazing 1y ago
    Type O Negative here, they all kill me so luckily I don't have to guess!
  - HarHarVeryFunny 1y ago
    Does the concept of O -ve as a universal donor type apply at all outside of the ABO group, and am I understanding correctly from your comment that even within the APO group O -ve compatibility would still be subject to this antigen matching? Don't we have synthetic blood, at least capable of transporting oxygen ?
    - kadoban 1y ago
      There's not really a synthetic oxygen-carrying blood substitute that's commonly used. Turns out it's actually pretty hard to get right. https://en.wikipedia.org/wiki/Blood_substitute https://en.wikipedia.org/wiki/Blood_substitute has some info on different approaches and products that were/are sometimes used, but the short story is: not really.
firtoz 1y ago
[flagged]
- petre 1y ago
  No worries, they won't go to set up blind dates with Guadelupians.
- paxys 1y ago
  Still more reasonable than basing your entire personality on the month you were born.
  - BrandoElFollito 1y ago
    [flagged]
    - Out_of_Characte 1y ago
      That's where correlations of random events and placebo end and where discovery begins. There are 'gods' that are 'better' than others. Even if the principle of what you/people believe goes against what you find scientifically relevent, or factual, or sensible. There still is something to be said about a group of people following a strange set of rules that could be demonstrably better than other sets of rules and beliefs. May it be enviromental, genetic, placebo or a tiny edge over what gives life meaning. We ended up with the gods we have today, not by coincidence, but because all the other ones failed their followers.
      - deleted 1y ago
        [deleted]
      - ajuc 1y ago
        Religions compete by "virality", like viruses they evolve towards encouraging reproduction. Even if you measure "better" as "more viral" - it's not "gods" who are better - it's cultural memes (for example there's 1000 versions of christianity believing in the same gods with vastly different cultures and virality outcomes).
curtisszmania 1y ago
[dead]
kimos 1y ago
My clearly incorrect understanding was that there are ~8 blood types. So reading that there are 48 is shocking.
- AnotherGoodName 1y ago
  The other thing people should have more awareness of is that plasma and blood have opposite compatibilities; a universal plasma donor will have blood only compatible to their blood type and vice versa. Which makes the hollywood trope of ‘i’m a universal donor’ really silly. Universal donor of what? And then they pump the blood and plasma straight into the other person pretty much guaranteeing problems since either the blood or plasma will be incompatible. The only reason blood donation works is due to machines that separate the blood and plasma.
  - greggsy 1y ago
    When people are directly piped to each other in movies, I often wonder if there is some negotiation protocol like PD that ensures that the donor continues to charge the recipient, even when their capacities both reach equilibrium.
- nick238 1y ago
  There are 48 blood type systems, of which ABO (giving A, B, AB, and O) and Rh (+/-) can be combined to form the 8 common types. There are effectively millions of types because all the systems combined combinatorially, but most antigens beyond ABO and Rh don't cause that much of an issue, so in emergency cases, they just go with them.
  - hinkley 1y ago
    Is that what’s going on with organ matching?
    - thecrims0nchin 1y ago
      Abo is a major part of organ matching. Abo has to be considered for any organ transplant. Every organ differs but HLA antigens is a different, more complex set of antigens that needs to be matched to some degree as well. Abo is usually a simple test, so hla antigen matching is most of what "organ matching" labs spend their time on. I work in this field.
thaumasiotes 1y ago
> The discovery of new blood types isn't limited to transfusion emergencies. It also sheds light on certain previously unexplained pathologies. The specialist discusses the recent case of three siblings who had suffered from mysterious rheumatological disorders since adolescence. It was only after identifying their rare blood type that doctors were able to establish a probable link with their symptoms. How does that work? Were all three siblings regularly receiving donated blood? The article doesn't expand on this at all.
- spondylosaurus 1y ago
  I read it to mean that the rheumatological symptoms they had were the result of their unusual blood type. Hard to say without more info, but something about that particular blood type could be linked to an inflammatory disorder.

184 points by spidersouris 1y ago

deleted 1y ago

[deleted]

kalium-xyz 1y ago

This is one of those things that doesnt matter most of the time but when it matters it really matters.

xyst 1y ago

It’s cool to see these discoveries, but as a patient. It’s probably a nightmare to be unique in this aspect. If American, think higher costs of care. If involved in car accident or other traumatic injury outside of normal area, good luck getting your blood transfused. Might get lucky with substitute. Surgery preparation also more complicated. Maybe you have competent medical staff that recognize it. Maybe a few hematologists in the world familiar with your blood and history. Maybe a few neurons fire off in the back of an aging emergency physician that recalls this in a case study he/she read about in medical school/residency.

escapecharacter 1y ago

Manga lore fan wikis about to go nuts...

PokemonNoGo 1y ago
Why?
- muzani 1y ago
  Japanese culture looks at blood type as indicative of personality, like horoscopes.

waltercool 1y ago

[dead]

tetris11 1y ago

I wonder why they named it PIGZ

ajb 1y ago

The OP is low on details. There is more in this article (in french): https://www.lindependant.fr/2025/06/21/il-ny-a-quelle-qui-est-compatible-avec-elle-meme-aujourdhui-dans-le-monde-un-nouveau-groupe-sanguin-decouvert-chez-une-francaise-12776910.php https://www.lindependant.fr/2025/06/21/il-ny-a-quelle-qui-es... Apparently the ISBT have added this to their list: https://www.isbtweb.org/isbt-working-parties/rcibgt.html https://www.isbtweb.org/isbt-working-parties/rcibgt.html (the page still says 47 but the data tables have it added)

xattt 1y ago
Neither article talks about whether this is a minor or a major antigen. Blood for transfusion needs to be crossmatched against antigen types of the recipient. Many patients will tolerate several transfusions of a minor mismatched antigen before developing a sensitivity. Major antigens are what cause significant reactions that can be life-threatening. Minor antigens come into play when crossmatching for infants and premies, but this is way beyond my scope.
- mmazing 1y ago
  Type O Negative here, they all kill me so luckily I don't have to guess!
- HarHarVeryFunny 1y ago
  Does the concept of O -ve as a universal donor type apply at all outside of the ABO group, and am I understanding correctly from your comment that even within the APO group O -ve compatibility would still be subject to this antigen matching? Don't we have synthetic blood, at least capable of transporting oxygen ?
  - kadoban 1y ago
    There's not really a synthetic oxygen-carrying blood substitute that's commonly used. Turns out it's actually pretty hard to get right. https://en.wikipedia.org/wiki/Blood_substitute https://en.wikipedia.org/wiki/Blood_substitute has some info on different approaches and products that were/are sometimes used, but the short story is: not really.

firtoz 1y ago

[flagged]

petre 1y ago
No worries, they won't go to set up blind dates with Guadelupians.
paxys 1y ago
Still more reasonable than basing your entire personality on the month you were born.
- BrandoElFollito 1y ago
  [flagged]
  - Out_of_Characte 1y ago
    That's where correlations of random events and placebo end and where discovery begins. There are 'gods' that are 'better' than others. Even if the principle of what you/people believe goes against what you find scientifically relevent, or factual, or sensible. There still is something to be said about a group of people following a strange set of rules that could be demonstrably better than other sets of rules and beliefs. May it be enviromental, genetic, placebo or a tiny edge over what gives life meaning. We ended up with the gods we have today, not by coincidence, but because all the other ones failed their followers.
    - deleted 1y ago
      [deleted]
    - ajuc 1y ago
      Religions compete by "virality", like viruses they evolve towards encouraging reproduction. Even if you measure "better" as "more viral" - it's not "gods" who are better - it's cultural memes (for example there's 1000 versions of christianity believing in the same gods with vastly different cultures and virality outcomes).

curtisszmania 1y ago

[dead]

kimos 1y ago

My clearly incorrect understanding was that there are ~8 blood types. So reading that there are 48 is shocking.

AnotherGoodName 1y ago
The other thing people should have more awareness of is that plasma and blood have opposite compatibilities; a universal plasma donor will have blood only compatible to their blood type and vice versa. Which makes the hollywood trope of ‘i’m a universal donor’ really silly. Universal donor of what? And then they pump the blood and plasma straight into the other person pretty much guaranteeing problems since either the blood or plasma will be incompatible. The only reason blood donation works is due to machines that separate the blood and plasma.
- greggsy 1y ago
  When people are directly piped to each other in movies, I often wonder if there is some negotiation protocol like PD that ensures that the donor continues to charge the recipient, even when their capacities both reach equilibrium.
nick238 1y ago
There are 48 blood type systems, of which ABO (giving A, B, AB, and O) and Rh (+/-) can be combined to form the 8 common types. There are effectively millions of types because all the systems combined combinatorially, but most antigens beyond ABO and Rh don't cause that much of an issue, so in emergency cases, they just go with them.
- hinkley 1y ago
  Is that what’s going on with organ matching?
  - thecrims0nchin 1y ago
    Abo is a major part of organ matching. Abo has to be considered for any organ transplant. Every organ differs but HLA antigens is a different, more complex set of antigens that needs to be matched to some degree as well. Abo is usually a simple test, so hla antigen matching is most of what "organ matching" labs spend their time on. I work in this field.

thaumasiotes 1y ago

> The discovery of new blood types isn't limited to transfusion emergencies. It also sheds light on certain previously unexplained pathologies. The specialist discusses the recent case of three siblings who had suffered from mysterious rheumatological disorders since adolescence. It was only after identifying their rare blood type that doctors were able to establish a probable link with their symptoms. How does that work? Were all three siblings regularly receiving donated blood? The article doesn't expand on this at all.

spondylosaurus 1y ago
I read it to mean that the rheumatological symptoms they had were the result of their unusual blood type. Hard to say without more info, but something about that particular blood type could be linked to an inflammatory disorder.