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Taurine and aging: Is there anything to it?
- jbentley1 1y agoRead the first couple lines, closed the page, and concluded that I should drink more Red Bull.
- meindnoch 1y agoA Downside of Taurine: It Drives Leukemia Growth https://www.urmc.rochester.edu/news/story/a-downside-of-taurine-it-drives-leukemia-growth https://www.urmc.rochester.edu/news/story/a-downside-of-taur...
- john-h-k 1y agoThis has to be taken as one of many data points. Many things that are good for your body will also drive increased cancer growth
- amelius 1y agoAnother downside: > Microbiologists have discovered a new intestinal microbe that feeds exclusively on taurine and produces the foul-smelling gas hydrogen sulfide. https://www.sciencedaily.com/releases/2023/09/230918105118.htm https://www.sciencedaily.com/releases/2023/09/230918105118.h...
- consumer451 1y agoI would really like to thank you for posting this comment. I shared the study with my stepfather, who is suffering from Leukemia, and is also taking a ridiculous number of various unregulated supplements. All of us in the family, and his top 1% doctors, have been trying to get him off of most them. It's been a losing battle so far. I shared the link that you posted, and it may have finally done the job.
- amelius 1y agoAnswer from TFA: no > But taken together, all of this new information makes me glad that I have not been loading up on the taurine for purposes of graceful aging, I can tell you that for sure.
- lentoutcry 1y agothis is the first time I’m hearing taurine had been linked in any way to aging (while also finding out that’s no longer supported by evidence). all I knew was that it’s something energy drinks have. but I’m curious, did this take off as a popular supplement?
- mark_l_watson 1y agoI understand that trying to take supplements to slow aging is a crap shoot. That said I take Taurine in the form of eating dark chicken meat, legs and thighs. I also take NAD+ with resveratrol as publicized by David Sinclair at Harvard. I believe that the very best thing to do to maintain health and perhaps have higher quality of life, later in life, is to meditate, forgive other people and yourself, and generally balance spirituality, good sleep, good food, and walk outside a few times a day. EDIT: left off two big things. As we age we need vitamin D supplements and I personally also believe in loading up on Omega 3 by eating walnuts, chia seeds, and salmon.
- jgilias 1y agoDon’t forget some type of strength training. There’s plenty of research that it reduces all cause mortality. Likely by pushing back the time you become frail.
- mark_l_watson 1y agoI should, but I don't. I do hike four hours a week and swim for a half hour every day very early in the morning. Thanks for the reminder, you are 100% correct. I am in my mid 70s, so I think I only need resistance training about twice a week.
- lagniappe 1y agoYou need it every day at that age to preserve bone density.
- bravesoul2 1y agoCitation?
- dakiol 1y agoNeed what exactly? Resistance training or strength training? Or both?
- deleted 1y ago
- paulcole 1y ago> Taurine and Aging: Is There Anything to It? Remember that you should only smugly refer to Betteridge’s Law of Headlines when you disagree with the article.
- baxtr 1y agoAfter looking a bit into the longevity stuff I’ve come to the conclusion that 80% of the benefits for health come from simple habits: sleep well, move daily, work-out regularly, eat fresh and moderately, and maintain social connections. That’s it.
- selfselfgo 1y agoIts funny to me, because there’s many strong studies that basically show the life expectancy for vegetarians is about 10 years higher, but most people including myself wouldn’t become a vegetarian despite the clear health benefits.
- mariusor 1y agoCouldn't this be, maybe, one of those "correlation is not causation" thingies?
- layer8 1y agoYeah, and I don’t expect any new simple solutions to suddenly be discovered either.
- valianteffort 1y agoThere are drugs like metformin which appear to have a drastic affect on lifespan in patients with or without diabetes. But yes generally, premature death seems to come from bad lifestyle choices over a lifetime, so being proactive is gonna yield the greatest return.
- the__alchemist 1y agoI take Metformin and don't have diabetes, but don't think there's much of a chance of significant benefits. Would expect diabetics etc to have noticably higher healthapans offset by the diabetes symptoms. It's been a heavily-taken drug for decades...
- giardini 1y ago
- robwwilliams 1y agoThe original taurine paper in Science was obviously a mess to some of us in the field. They did not even have plausible taurine concentrations. Poor review process. There is no reason to supplement with taurine or with resveratrol. Resveratrol debunked firmly by both the Interventions Testing Program in mice (Miller et al 2011, a paper with Sinclair as a coauthor) and earlirr by Timothy Bass and Linda Partridge and colleagues in two widely used model organisms (C elegans anf Drisophila, 2007). Yes David Sinclair is vocal and has a book: but look at the evidence and compare to rapamycin. Rapamycin is a drug with strong prolongevity effects at almost any age in both sexes at an appropriate dose to inhibit only mTOR-C1 signaling (4 to 8 mg once per week). There ARE side effects to almost any drug. And rapamycin will not be a good drug for a subset of humans in some environments. For example rapamycin is one if the last drugs I would take if I was caring for a room full of 5-6 year olds all day. But surprisingly it was a good drug to be taking during COVID-19 if you were older. perhaps by reducing the inflammatory hyper-vigilance that killed so many older humans. See Kaeberlein’s study of 333 biohackers in 2023.
- lentoutcry 1y agowhat about methylene blue? I saw an article around the other day saying basically that it’s mostly hype, but I’ve also heard good things about it.
- giardini 1y agoTough to handle though!8-)) It gets all over the place: stains skin, clothes, most everything else unless you handle it as if you were in a laboratory. Never thought about it before but handling MB in a chem lab might be a very good way to show beginning students how difficult it is to do good lab work and how easily traces of material (and organisms) may pass from one place to another (contact).
- the__alchemist 1y agoThe problem is RM as you know, is the negative effects from immunosuppression. Makes it tougher to justify than others.
- _xerces_ 1y agoI was taking taurine 1000 mg per day but stopped when I heard a plausible link to colon cancer. Having a strong family history, it wasn't worth the risk. Eagerly awaiting the results of this trial: https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.TPS3630 https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.TPS363... Uncertain though how they will separate the effects of the taurine from all the other stuff including sugar that is contained in energy drinks. I think this is a hard theory to pin down as it might depend on how much taurine producing bacteria an individual has in their gut B. wadsworthia, so two people could have very different outcomes while taking the same amount of taurine.
- OutOfHere 1y agoI can't speak for aging, but my strong personal experience with taurine tells me that it does help, a lot. It is excellent for anyone with dry eyes, which is a lot of people. It is also good for anyone who relies on caffeine a fair bit, which is why it's in energy drinks.
- simonebrunozzi 1y agoDerek is always the best.