8 ms·

She didn't even break the top 10 in this content: https://www.societyforscience.org/regeneron-sts/2025-student-finalists/ https://www.societyforscience.org/rege

by Mizza 1y ago

She didn't even break the top 10 in this content: https://www.societyforscience.org/regeneron-sts/2025-student-finalists/ https://www.societyforscience.org/regeneron-sts/2025-student... I'm impressed beyond words by these kids, though I think I'd give her the top prize. Watching my grandfather's final days taken away from him by the effects of morphine has always made me wish so much that we had much more effective non-narcotic painkillers

irjustin 1y ago
https://www.societyforscience.org/press-release/regeneron-isef-2025-full-awards/ https://www.societyforscience.org/press-release/regeneron-is... She's in top 4, awarded $600? I dunno this is a confusing layout/structure for how the program is conducted seeing as how the headline is $9m awarded.
ricardobeat 1y ago
Reversible computing, materials science, genetic research… it’s insane that these kids are doing this level of work in high school.
- deleted 1y ago
  [deleted]
- timr 1y ago
  They aren't doing it on their own. Most of these kids are working with established researchers who give them the shape of the project, as well as the tools and the expertise to accomplish it. More recently the US scientific funding bodies have had summer programs for kids who wouldn't otherwise get that kind of access, but it's still the exception. It takes more than a summer to do this kind of work. Edit: quick search for the father's name brings up this professor of biochemistry at UT Tyler: https://www.uttyler.edu/directory/chemistry/lee-jiyong.php https://www.uttyler.edu/directory/chemistry/lee-jiyong.php and mom's name brings up this professor of pharmaceutical science: https://www.unthsc.edu/college-of-pharmacy/eul-hyun-suh https://www.unthsc.edu/college-of-pharmacy/eul-hyun-suh I don't mean to take anything away from the kid or suggest that they don't work hard, are smart, etc., but these kinds of science fairs are fundamentally about access.
  - carlmr 1y ago
    >these kinds of science fairs are fundamentally about access. Completely agree there, which kind of brings me to a related thought: One thing I do wonder is, if you look at a few hundred years ago a lot of the inventors in math, physics, engineering, were a tiny group of people with access to resources and education. You're always reading the same names. It seems if we as a society could decide that science is more important to us, with 8 billion people on earth, if we gave more access, time and incentives to people we should be able to increase the amount of scientific results exponentially.
    - timr 1y ago
      Meh. While I think the broad theme is fine (more access to education is generally good -- particularly when it comes to scientific literacy amongst the general public!), I think trying to encourage "research" in this way is largely pushing on a string. I can never figure out if this whole phenomenon of "science fairs" is just Kabuki theater for everyone involved, or if there's a core group of deeply deluded organizers who really believe that they're Making A Difference (tm) in scientific research, and are just completely blind to the career prospects of actual young scientists [1]. Time and experience has shown that "scientific innovation" cannot be made to happen faster by throwing more money at it, and a promising young person would be much better off by putting their talents to use doing something less random [2]. You can produce more good research in aggregate (maybe), but only in the same way that you can find more gold by crushing more rocks. Either way, you have to crush the rocks. For example, the US government dramatically increased grad school funding through the 80s-2000s, and the primary outcome was an employment crisis amongst PhDs in the sciences. In the 40s-70s it was fairly straightforward to establish a career in research, but these days it's Hunger Games. I sort of fundamentally believe that the reason most science came out of the European aristocracy was not due to inequity, but because only someone well-off could devote their lives to something so erratic. Science is an avocation, not a vocation. Science fairs and the like are a weird little subculture of college-application polishers, in part because nobody in their right mind actually wants to become a scientist. I think it's a safe bet that the young woman in this article ends up doing something more lucrative with her life (and good for her, if she does). [1] Or even more cynically: the organizers do know, and are doing it because it builds their own careers. [2] Or at least, with a higher alpha.
- AStonesThrow 1y ago
  Science projects are a family affair, more often than not. Ask me how I know.
fracus 1y ago
I thought morphine didn't cause health damage to the human body apart from addiction and withdrawal symptoms.
- lenerdenator 1y ago
  at least according to these people [0], you can overdose on morphine, same as any opiate or opioid. not sure their credentials but it makes sense; it's an opioid/opiate and those can cause respiratory depression. [0]https://www.addictiongroup.org/drugs/opioids/morphine/overdose/ https://www.addictiongroup.org/drugs/opioids/morphine/overdo...
  - DontchaKnowit 1y ago
    Yeah its like any other opiod- it depresses respiratory function which can cause death but it isnt directly toxic to any organs like APAP is
  - dreamcompiler 1y ago
    Oh yeah morphine overdose will kill you dead because you will stop breathing and you won't even know it happened. The instant antidote is Narcan which is available over the counter at pharmacies in some states.
- shanemhansen 1y ago
  Well it absolutely muddles your mind when you're on it and it causes constipation. It can also depress your respiratory system.
  - dreamcompiler 1y ago
    And it can make some people very nauseous. Nobody discusses these mundane drawbacks when they talk about the evils of heroin addiction. When you're high, you puke and you cannot give a shit. Both figuratively and literally.
  - johnisgood 1y ago
    Not everyone experiences side-effects of opioids, in fact, they are not even THAT common. I do not experience euphoria, nausea, mental fog, or any sedation from ANY opioids. I experience constipation, but I am fine with that. Morphine might be more dulling (or foggy) than say, oxycodone, but it highly varies. As for "depress your respiratory system", yeah, in high enough doses, or if you are especially sensitive to it. Pharmaceutical opioids are pretty much safer than NSAIDs. The side-effects of NSAIDs are actually worse than the side-effect of opioids. You will not get ulcers, blood clots, stroke, heart issues, GI issues, and all sorts of other issues with opioids.
apwell23 1y ago
> Watching my grandfather's final days taken away from him by the effects of morphine Those were not prbly his final days. he was artifically kept alive by modern medicine. Those final days are not natural part of dying.
petesergeant 1y ago
Journavx!
adamredwoods 1y ago
I'm pro-morphine as a controlled medicine for extreme pain and end-of-life. I've seen it work. I've had it post-surgery. Fentanyl, my brother claims to be the best. It, too, can work wonders under a controlled environment.
- const_cast 1y ago
  Fentanyl is pretty much better than morphine in every way. Less toxic, cheaper, and works better with less side-effects. Especially less histamine response, which is the body itching people get. Unfortunately, it's tainted by illicit use. Damned to only be used in dire circumstances. It's a shame, really.

by Mizza 1y ago

irjustin 1y ago

https://www.societyforscience.org/press-release/regeneron-isef-2025-full-awards/ https://www.societyforscience.org/press-release/regeneron-is... She's in top 4, awarded $600? I dunno this is a confusing layout/structure for how the program is conducted seeing as how the headline is $9m awarded.

ricardobeat 1y ago

Reversible computing, materials science, genetic research… it’s insane that these kids are doing this level of work in high school.

deleted 1y ago
[deleted]
timr 1y ago
They aren't doing it on their own. Most of these kids are working with established researchers who give them the shape of the project, as well as the tools and the expertise to accomplish it. More recently the US scientific funding bodies have had summer programs for kids who wouldn't otherwise get that kind of access, but it's still the exception. It takes more than a summer to do this kind of work. Edit: quick search for the father's name brings up this professor of biochemistry at UT Tyler: https://www.uttyler.edu/directory/chemistry/lee-jiyong.php https://www.uttyler.edu/directory/chemistry/lee-jiyong.php and mom's name brings up this professor of pharmaceutical science: https://www.unthsc.edu/college-of-pharmacy/eul-hyun-suh https://www.unthsc.edu/college-of-pharmacy/eul-hyun-suh I don't mean to take anything away from the kid or suggest that they don't work hard, are smart, etc., but these kinds of science fairs are fundamentally about access.
- carlmr 1y ago
  >these kinds of science fairs are fundamentally about access. Completely agree there, which kind of brings me to a related thought: One thing I do wonder is, if you look at a few hundred years ago a lot of the inventors in math, physics, engineering, were a tiny group of people with access to resources and education. You're always reading the same names. It seems if we as a society could decide that science is more important to us, with 8 billion people on earth, if we gave more access, time and incentives to people we should be able to increase the amount of scientific results exponentially.
  - timr 1y ago
    Meh. While I think the broad theme is fine (more access to education is generally good -- particularly when it comes to scientific literacy amongst the general public!), I think trying to encourage "research" in this way is largely pushing on a string. I can never figure out if this whole phenomenon of "science fairs" is just Kabuki theater for everyone involved, or if there's a core group of deeply deluded organizers who really believe that they're Making A Difference (tm) in scientific research, and are just completely blind to the career prospects of actual young scientists [1]. Time and experience has shown that "scientific innovation" cannot be made to happen faster by throwing more money at it, and a promising young person would be much better off by putting their talents to use doing something less random [2]. You can produce more good research in aggregate (maybe), but only in the same way that you can find more gold by crushing more rocks. Either way, you have to crush the rocks. For example, the US government dramatically increased grad school funding through the 80s-2000s, and the primary outcome was an employment crisis amongst PhDs in the sciences. In the 40s-70s it was fairly straightforward to establish a career in research, but these days it's Hunger Games. I sort of fundamentally believe that the reason most science came out of the European aristocracy was not due to inequity, but because only someone well-off could devote their lives to something so erratic. Science is an avocation, not a vocation. Science fairs and the like are a weird little subculture of college-application polishers, in part because nobody in their right mind actually wants to become a scientist. I think it's a safe bet that the young woman in this article ends up doing something more lucrative with her life (and good for her, if she does). [1] Or even more cynically: the organizers do know, and are doing it because it builds their own careers. [2] Or at least, with a higher alpha.
AStonesThrow 1y ago
Science projects are a family affair, more often than not. Ask me how I know.

fracus 1y ago

I thought morphine didn't cause health damage to the human body apart from addiction and withdrawal symptoms.

lenerdenator 1y ago
at least according to these people [0], you can overdose on morphine, same as any opiate or opioid. not sure their credentials but it makes sense; it's an opioid/opiate and those can cause respiratory depression. [0]https://www.addictiongroup.org/drugs/opioids/morphine/overdose/ https://www.addictiongroup.org/drugs/opioids/morphine/overdo...
- DontchaKnowit 1y ago
  Yeah its like any other opiod- it depresses respiratory function which can cause death but it isnt directly toxic to any organs like APAP is
- dreamcompiler 1y ago
  Oh yeah morphine overdose will kill you dead because you will stop breathing and you won't even know it happened. The instant antidote is Narcan which is available over the counter at pharmacies in some states.
shanemhansen 1y ago
Well it absolutely muddles your mind when you're on it and it causes constipation. It can also depress your respiratory system.
- dreamcompiler 1y ago
  And it can make some people very nauseous. Nobody discusses these mundane drawbacks when they talk about the evils of heroin addiction. When you're high, you puke and you cannot give a shit. Both figuratively and literally.
- johnisgood 1y ago
  Not everyone experiences side-effects of opioids, in fact, they are not even THAT common. I do not experience euphoria, nausea, mental fog, or any sedation from ANY opioids. I experience constipation, but I am fine with that. Morphine might be more dulling (or foggy) than say, oxycodone, but it highly varies. As for "depress your respiratory system", yeah, in high enough doses, or if you are especially sensitive to it. Pharmaceutical opioids are pretty much safer than NSAIDs. The side-effects of NSAIDs are actually worse than the side-effect of opioids. You will not get ulcers, blood clots, stroke, heart issues, GI issues, and all sorts of other issues with opioids.

apwell23 1y ago

> Watching my grandfather's final days taken away from him by the effects of morphine Those were not prbly his final days. he was artifically kept alive by modern medicine. Those final days are not natural part of dying.

petesergeant 1y ago

Journavx!

adamredwoods 1y ago

I'm pro-morphine as a controlled medicine for extreme pain and end-of-life. I've seen it work. I've had it post-surgery. Fentanyl, my brother claims to be the best. It, too, can work wonders under a controlled environment.

const_cast 1y ago
Fentanyl is pretty much better than morphine in every way. Less toxic, cheaper, and works better with less side-effects. Especially less histamine response, which is the body itching people get. Unfortunately, it's tainted by illicit use. Damned to only be used in dire circumstances. It's a shame, really.