3 ms·

DEHT exposure)

49 points by nabla9 2y ago

deleted 2y ago
[deleted]
nabla9 2y ago
https://www.sciencedirect.com/science/article/abs/pii/S0013935124013707 https://www.sciencedirect.com/science/article/abs/pii/S00139... Highlights * Silicone wristbands were used to quantify exposure across two different cohorts. * Human exposure to ortho-phthalates and non-ortho-phthalate plasticizers is ubiquitous. * DiNP, DEHP, and DEHT accounted for 94–97% of human exposure. * Our findings raise concerns about chronic DEHP/DiNP/DEHT exposure in urban areas.
bloopernova 2y ago
oof, DiNP, DEHP, and DEHT can have deleterious effects upon cells: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316248/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316248/ (2022) "Effects of DEHP, DEHT and DINP Alone or in a Mixture on Cell Viability and Mitochondrial Metabolism of Endothelial Cells In Vitro" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157593/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157593/ (2021) "Phthalates and Their Impacts on Human Health" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842715/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842715/ (2018) "Toxic Effects of Di-2-ethylhexyl Phthalate: An Overview" https://pubmed.ncbi.nlm.nih.gov/31577137/ https://pubmed.ncbi.nlm.nih.gov/31577137/ (2019) "DEHP and DINP Induce Tissue- and Gender-Specific Disturbances in Fatty Acid and Lipidomic Profiles in Neonatal Mice: A Comparative Study" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504421/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504421/ (2020) "Structure-Dependent Effects of Phthalates on Intercellular and Intracellular Communication in Liver Oval Cells"
jmclnx 2y ago
Going after plastic manufactures in a similar manner as the US did to tobacco should be a no brainer. Tobacco companies had a very very weak argument that people born after a specific date used it on purpose (after the warnings were required on the product). Before that date, people believed it was safe due to ads. But plastic people have no such argument. Health issues are yet to be fully confirmed. But after about 50 years of plastic being everywhere in the environment, we see alarming increases in many health issues among the young. The young have been exposed to plastics since conception. To me, that is a rather big coincidence. Are they related ? Only more research will tell, but everyone now has mirco-plastics in their systems. Seems this is like the mercury build up that happen a long time ago. Eat organisms with micro-plastic in their system, it builds up in your system.
- infecto 2y ago
  You are missing a part of that no brainer argument. What do you do with all the products that use plastic. You go after big plastic and then what? Unlike tobacco, plastic is used in most/all of our day to day products. This is not a defense of big plastic but rather pushing for the real issue, who do you transition from plastics?
  - zug_zug 2y ago
    Maybe you put a 500% tariff (at least, since plastic is such a cheap product) on the most dangerous plastics (the ones that are known to disrupt hormones). Also a domestic plastic tax - by making plastic less cheap (perhaps have it go up 10% every year in perpetuity) eventually there will be incentives to find natural alternatives (paper, bamboo, woods, etc). It makes no sense to me to claim the most productive country in all of history, with our AI and everything, couldn't replace plastic. It's the same thing people said about oil 50 years ago.
    - infecto 2y ago
      But oil is just as relevant today as it was 50 years ago, even when accounting for renewables. Nobody is claiming it cannot be done but I believe its very valid to point out that it is not a no brainer and the implications on the global economy may be quite severe. Again not a defense of plastic but more that I think its more complicated than people make it out to be.
  - jmclnx 2y ago
    For many items, bottles. I was quite young before plastics became impossible to avoid, so I remember how things were. As for other things, maybe aluminum for say phone and laptop cases and other items for autos. I doubt we can eliminate all plastic, but I think we can eliminate most of it. Yes, things would be more expensive, but we have a choice, Health or Plastic. If you factor in the cost of healthcare, then the extra expense may be a wash. It is just a matter of who pays.
  - Arn_Thor 2y ago
deleted 2y ago
[deleted]
deleted 2y ago
[deleted]
DoingIsLearning 2y ago
They mentioned 'airborne' but how do they distinguish plasticizers introduced by airborne particles and plasticizers introduced by showering or washing hands and rubbing detergents on the wristband for example?
seniortaco 2y ago
Sidenote, why is silicone able to accumulate so many airborne chemicals for testing? Tons of food/kitchen products are made of silicone and touted as food safe. However, I always find that silicone kitchen products accumulate smells and then transfer these odors to the food, so I abhor them. This seems to confirm that mechanism.

49 points by nabla9 2y ago

deleted 2y ago

[deleted]

https://www.sciencedirect.com/science/article/abs/pii/S0013935124013707 https://www.sciencedirect.com/science/article/abs/pii/S00139... Highlights * Silicone wristbands were used to quantify exposure across two different cohorts. * Human exposure to ortho-phthalates and non-ortho-phthalate plasticizers is ubiquitous. * DiNP, DEHP, and DEHT accounted for 94–97% of human exposure. * Our findings raise concerns about chronic DEHP/DiNP/DEHT exposure in urban areas.

bloopernova 2y ago

oof, DiNP, DEHP, and DEHT can have deleterious effects upon cells: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316248/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316248/ (2022) "Effects of DEHP, DEHT and DINP Alone or in a Mixture on Cell Viability and Mitochondrial Metabolism of Endothelial Cells In Vitro" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157593/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157593/ (2021) "Phthalates and Their Impacts on Human Health" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842715/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842715/ (2018) "Toxic Effects of Di-2-ethylhexyl Phthalate: An Overview" https://pubmed.ncbi.nlm.nih.gov/31577137/ https://pubmed.ncbi.nlm.nih.gov/31577137/ (2019) "DEHP and DINP Induce Tissue- and Gender-Specific Disturbances in Fatty Acid and Lipidomic Profiles in Neonatal Mice: A Comparative Study" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504421/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504421/ (2020) "Structure-Dependent Effects of Phthalates on Intercellular and Intracellular Communication in Liver Oval Cells"

jmclnx 2y ago

Going after plastic manufactures in a similar manner as the US did to tobacco should be a no brainer. Tobacco companies had a very very weak argument that people born after a specific date used it on purpose (after the warnings were required on the product). Before that date, people believed it was safe due to ads. But plastic people have no such argument. Health issues are yet to be fully confirmed. But after about 50 years of plastic being everywhere in the environment, we see alarming increases in many health issues among the young. The young have been exposed to plastics since conception. To me, that is a rather big coincidence. Are they related ? Only more research will tell, but everyone now has mirco-plastics in their systems. Seems this is like the mercury build up that happen a long time ago. Eat organisms with micro-plastic in their system, it builds up in your system.

infecto 2y ago
You are missing a part of that no brainer argument. What do you do with all the products that use plastic. You go after big plastic and then what? Unlike tobacco, plastic is used in most/all of our day to day products. This is not a defense of big plastic but rather pushing for the real issue, who do you transition from plastics?
- zug_zug 2y ago
  Maybe you put a 500% tariff (at least, since plastic is such a cheap product) on the most dangerous plastics (the ones that are known to disrupt hormones). Also a domestic plastic tax - by making plastic less cheap (perhaps have it go up 10% every year in perpetuity) eventually there will be incentives to find natural alternatives (paper, bamboo, woods, etc). It makes no sense to me to claim the most productive country in all of history, with our AI and everything, couldn't replace plastic. It's the same thing people said about oil 50 years ago.
  - infecto 2y ago
    But oil is just as relevant today as it was 50 years ago, even when accounting for renewables. Nobody is claiming it cannot be done but I believe its very valid to point out that it is not a no brainer and the implications on the global economy may be quite severe. Again not a defense of plastic but more that I think its more complicated than people make it out to be.
- jmclnx 2y ago
  For many items, bottles. I was quite young before plastics became impossible to avoid, so I remember how things were. As for other things, maybe aluminum for say phone and laptop cases and other items for autos. I doubt we can eliminate all plastic, but I think we can eliminate most of it. Yes, things would be more expensive, but we have a choice, Health or Plastic. If you factor in the cost of healthcare, then the extra expense may be a wash. It is just a matter of who pays.
- Arn_Thor 2y ago

deleted 2y ago

[deleted]

deleted 2y ago

[deleted]

DoingIsLearning 2y ago

They mentioned 'airborne' but how do they distinguish plasticizers introduced by airborne particles and plasticizers introduced by showering or washing hands and rubbing detergents on the wristband for example?

seniortaco 2y ago

Sidenote, why is silicone able to accumulate so many airborne chemicals for testing? Tons of food/kitchen products are made of silicone and touted as food safe. However, I always find that silicone kitchen products accumulate smells and then transfer these odors to the food, so I abhor them. This seems to confirm that mechanism.