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The unknowns surrounding the mysterious rise of cancer in young adults
- seydor 2y ago[flagged]
- dathos 2y agoAnyone aware of the possible correlation between this and forever chemicals found in humans increasing? I don’t see it mentioned in the article
- blueflow 2y agoPFAS are big in media right now but likely not the main cause.
- Brybry 2y agoIf I had to guess I'd think microplastics[1] because we actively consume them and they're found in our tissues and they didn't really exist before the 50s/60s. But I haven't seen any research showing correlations in real human beings yet. [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340669/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340669/
- Aardwolf 2y agoTangentially related question: one cause of cancer would be lack of physical activity (https://www.who.int/news-room/fact-sheets/detail/cancer https://www.who.int/news-room/fact-sheets/detail/cancer). What's the mechanism of this? Cancer is caused by bad-luck random cell division creating a bad cell, I can see how chemicals influence this process, but how does physical activity?
- blueflow 2y agoHigher fitness -> higher chance the immune system will kill the rogue cells on its own.
- bdjsiqoocwk 2y agoWhat's the mechanism behind that? Being "more fit" is not exactly one single thing.
- xdavidliu 2y agois it obvious that good fitness is related to good immune function?
- blueflow 2y agoIt seems obvious when you see your own body aging and slowly loose both.
- TeMPOraL 2y agoI'd expect the opposite: higher fitness -> immune system more busy with repairing wear&tear. Lower fitness -> immune system bored and more reactive to any suspicious cellular activity.
- inciampati 2y agoThe repair of the wear and tear seems to provide more opportunities for the body to reject cancers. Also, aerobic activity may encourage selection for oxidative metabolism which is very suppressed in most cancers. It's counterintuitive but the epidemiology is very clear that exercise is protective. It doesn't wear you out faster but rather helps you rebuild and maintain yourself more rapidly (without which, you wear out).
- dahart 2y agoThat might be true in the extreme ends, say for Ironman athletes, but a bit misleading as a summary since we already have lots of data that moderate exercise correllates with reduced risks of everything from getting a cold to heart disease. If we’re comparing to people who don’t exercise, the alternative should be moderate exercise, not high intensity training. Also a bored and over-reactive immune system can be a pretty bad thing.
- candiddevmike 2y ago> The BMJ Oncology study concludes that “dietary risk factors, alcohol consumption, and tobacco use were the main risk factors for major early-onset cancers.” But it adds that “prospective lifetime cohort studies are needed to explore the etiologies [causes] of early-onset cancers.” Whatever we're consuming is most likely the culprit (or whatever is being sprayed on/injected into/fed to what we're consuming).
- Iulioh 2y agoIsn't tobacco and alcohol at a high time low in the younger generations?
- candiddevmike 2y agoAIUI gen z is slightly more health focused and has lower alcohol usage. Millennials and gen x make up for it.
- dbish 2y agoNot to mention that they’ve cut out alcohol but added vapes and what seems to be a healthy amount of marijuana. I don’t think that makes them healthier overall.
- whimsicalism 2y agocutting out smoking and alcohol and subbing in vapes and marijuana is almost certainly a net win healthwise
- dclowd9901 2y agoUnless it isn’t. Frankly we don’t know what the long term effects of vaping and marijuana usage are because we’ve not really dug into them.
- 2y ago
- AtlasBarfed 2y agoExercise/fitness/activity would be primary suspicion, which is also diet. You need a very high level of activity in order to properly exist in today's high carbohydrate corn syrup food base Permoplastics might have a roll but you figure that would have showed up by now a lot earlier. It could also be binge drinking. The culture of binge drinking has been steadily compounding itself over several generations of college students. But that may be an American phenomenon. This is a global one and it may not apply.
- mglz 2y agoThe article seems to skip over the pandemic, which has changed behaviours significantly. Also, the Coronavirus itself is suspected to promote cancer [1]. [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202899/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202899/
- candiddevmike 2y agoThere is some correlation between COVID exhausting certain white blood cells that fight cancer: https://www.nature.com/articles/s41423-021-00750-4 https://www.nature.com/articles/s41423-021-00750-4
- ekianjo 2y agoyes and then there is the elephant in the room nobody talks about: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184721/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184721/
- deleted 2y ago[deleted]
- logicchains 2y agoThe pseudouridine in the current generation of mRNA vaccines has also been demonstrated to promote cancer growth: https://www.sciencedirect.com/science/article/abs/pii/S0141813024022323?via%3Dihub https://www.sciencedirect.com/science/article/abs/pii/S01418...
- pimlottc 2y agoThe study in question looks at data from before the pandemic: "Global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019"
- dahart 2y agoIt’s almost certainly much too early to have any data on the relationship between the pandemic and cancer. Cancer causing factors may take decades to turn into detectable cancers, and even if the data were available, publishing them can take a couple of years on top.
- logicchains 2y agoClimate change strikes again. It has no end of unexpected consequences.
- maherbeg 2y agoThere’s been another hypothesis around the wider spread use of emulsifiers, specifically in lower fat foods. Lots of people are eating “healthy” almost whole food sources that contain them.
- anon84873628 2y agoYou should at least post a link to some source when spreading these rumors.
- rrr_oh_man 2y agohttps://pubmed.ncbi.nlm.nih.gov/38349899/ https://pubmed.ncbi.nlm.nih.gov/38349899/ Not a rumour.
- golanggeek 2y ago> The BMJ Oncology study concludes that “dietary risk factors, alcohol consumption, and tobacco use were the main risk factors for major early-onset cancers.” But it adds that “prospective lifetime cohort studies are needed to explore the etiologies [causes] of early-onset cancers.” > In the UK, specialists have specifically flagged up the risks of processed foods, which includes ready-made meals and pizzas, which young people tend to consume more of. Food seems to be the main culprit..
- jb1991 2y agothere is also an extraordinary amount of plastic and chemicals getting absorbed by nearly all food, as per a study last week: https://edition.cnn.com/2024/09/16/health/food-packaging-chemical-toxins-study-wellness/index.html https://edition.cnn.com/2024/09/16/health/food-packaging-che...
- linsomniac 2y agoAs a small data set, my mother and grandparents all smoked like there was no tomorrow and drank plenty, but never had any cancer issues. Though my mother and grandfather both had COPD, my mother in particular spent the last few years of her too-short life (late 60s) basically drowning because she couldn't expel the CO2. Prepared and ultra-processed foods, gut feel, seem to be a huge problem in many ways. A buddy of mine, his girlfriend is a big health nut and her rule of thumb is: Don't eat anything that has more than 4 ingredients or comes in a bag, and that seems like a good idea to me.
- deleted 2y ago[deleted]
- gklitz 2y agoHere is some general advice about how to translate between “your life” and statistics. Imagine that some new product gets released that increases your chance of chancer by 10x, so something extremely bad and very noticeable in studies. Now let’s say 2/10000 typically get this type of cancer normally and that it’s an extremely popular product so 50% of the world population use it. Start consuming it straight away. That leads us to having 2/10000 cases before the product and 7/10000 afterwards, and you’ll have 4994/5000 of people who use the OBVIUSLY bad product stating confidently that there can’t be any issue, because they aren’t effected. Imagine they all have 2 kids who have two kids and suddenly the common sense attitude that “this can’t be dangerous because my grand parents…” is the overwhelming majority opinion. You don’t have “a small dataset” you only have a bias, nothing more, nothing less. You can’t translate between data and your personal life how you’d expect to, it’s just not possible. Also regarding your buddies girlfriend’s advice she’s completely wrong. It’s actually anything with less than 3 ingredients or more than 5 but less than 7 you shouldn’t eat. Everything else is safe. You can trust me because “I’m a huge health nut”. Disclaimer: numbers might be slightly off, corrections are appreciated, but the point stands.
- m3kw9 2y agoAll the crap drinks they are promoting to young kids like Prime or redbull so prevailent in social media could be a factor
- piuantiderp 2y ago[flagged]
- walthamstow 2y ago> people born in 1990 [have] a significantly higher rate of developing colorectal cancer compared to people born in 1950 Wow. As someone born in 1990 +/- 2 years that's a statistic that will fester in ny mind.
- tjpnz 2y agoThat's the kind which scares me the most given how quickly it can grow and spread without any symptoms. Feel really fortunate to live in a country where screening starts at thirty years. Back home I would have to be well into my fifties.
- cjbgkagh 2y agoI think it’s from dysautonomia impairing the immune system. Pretty much anything that affects the autonomic nervous system, which is a huge number of very different things, can trigger dysautonomia. The rational for my reasoning is that the propensity for cancer appears to occur at roughly the same rate as the propensity for dysautonomia regardless of the cause of dysautonomia. Covid and the Covid Vaccine are both triggers for dysautonomia, I presume because both use the spike protein. The vaccine triggered mine but I have a strong genetic propensity for it anyway with multiple inherited anxiety disorders.
- b0dhimind 2y ago<in a snarly medical tyranny voice> NIE, you will have zeh vackzine! Jokes aside though, how is it that hard for people to connect the dots of what happened after "covid"? I guess because there are many other causes for cancer that have also increased since 2019 (poorer sleep quality, worse diets, depression, social isolation). But then again, forcibly injecting something with known carcinogens, into your blood that has since caused athletes and children to immediately collapse and die (or later on from myocarditis) should be overwhelming evidence of something akin to genocide.
- swayvil 2y agoThe vaccine?
- deleted 2y ago[deleted]
- Trebhawkins 2y agoObviously. It is the only recent nationwide (worldwide actually) environmental change. Might also ask about the plethora of athletes dropping dead or falling extremely ill on the playing field.
- krackers 2y agoI sure hope that the continuing sharply elevated rates of excess mortality [1,2] will be objectively and responsibly investigated so we can find the root cause. [1] https://www.bmj.com/company/newsroom/high-excess-death-rates-in-the-west-for-3-years-running-since-start-of-pandemic/ https://www.bmj.com/company/newsroom/high-excess-death-rates... [2] https://www.swissre.com/press-release/Covid-19-may-lead-to-longest-period-of-peacetime-excess-mortality-says-new-Swiss-Re-report/eadc133c-01bd-49e8-9f3a-a3025a3380e6 https://www.swissre.com/press-release/Covid-19-may-lead-to-l...
- capitainenemo 2y agoOne more possibility to throw on the pile.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860074/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860074/
- pvaldes 2y agoThe study cited is "Global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019". BMJ Oncology. 2023. Important context lacking here is that a scientist called Jianhui Zhao, has been caught cheating previously in a 2018 article about cancer. Results didn't matched the experiments. https://pubmed.ncbi.nlm.nih.gov/33901310/ https://pubmed.ncbi.nlm.nih.gov/33901310/ "certain of the Transwell cell migration and invasion assay data shown in Fig. 3B were strikingly similar to data appearing in different form in a pair of other articles written by different authors at different research institutes, one of which had already been published elsewhere prior to the submission of this paper to International Journal of Molecular Medicine" --If-- this author from the Second Affiliated Hospital on Zhejiang (China) is the same person that worked previously on the Hospital of Jilin University (China), we should take the results claimed here with a healthy dose of caution.
- ldehaan 2y ago[dead]
- woodpanel 2y agoOk, since many comments chip in subjective suggestions of who the culprit might be, here are my unsubstantiated reasons for rising cancer rates in young adults: china [1] higher education [2] [1] having spent time in China and seen how there is simply no remorse selling toxic waste as food, toys or skin care products I can’t see how western households, which are overproliferated with cheap goods made in China (i’d say 95% of everything a Westerner owns is made in PRC), aren’t affected by it. Put differently, why would China wait for its demographic Overton window to close and let its empire buildup be hampered by health concerns, let alone those of foreigners? [2] inflationary amounts of degree holders create more toxicity in the womb: Eggs are older and the mothers under a lot more stress (both parents need to work, societal pressure to not just excel in classic female fields, but also classic male domains, specifically academia)
- TacticalCoder 2y agoFrom when to when? What is badly needed is statistics before Covid hit and after Covid hit. And statistics by countries and depending on who got which vaccine and compared to people who didn't get the vaccine. P.S: FWIW I got the mRNA one from Pfizer/BioNTech and had I know what I know today I'd never have taken it.