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Sorry Pfizer, maybe we don't need to order billions of vaccines more but thank you for your service. Edit: this comment exploded, I was being sarcastic because
by arisAlexis 5y ago
Sorry Pfizer, maybe we don't need to order billions of vaccines more but thank you for your service.
Edit: this comment exploded, I was being sarcastic because Pfizer Ceo said confidently that we will all need frequent boosters like a good salesman would. And it's true that maybe it's prudent to buy boosters just in case.
- slver 5y agoThey still have billions to produce to cover us the first time.
- bart__ 5y agoIt is possible the spike proteins mutate too much and we need a booster
- wejn 5y agoThat'd be no (for natural immunity). Even SARS-1 survivors have immunity to COVID, all these years later. Maybe for the synthetic immunity (who knows). But in any case, SARS-1 and covid are about 80% similar. The "variants" of different covids are about 99.7% similar. Draw your own conclusions.
- bart__ 5y agoI did not know that, honestly quite surprised! One thing to keep in consideration is that there is a very big evolutionary pressure for covid to get a mutation that bypasses the vaccine antibodies and still infect others, given that there are so many active infections still out there. I now have good hope though!
- slver 5y agoYou didn't know that, because it's most likely BS. BTW people and chimpanzees share 99% of their DNA. We're basically the same, aren't we. /s 80% is not close at all, and 99.7% still can render a vaccine ineffective, of course the specifics matter.
- bart__ 5y agoTo be fair humans are almost identical to chimpanzees biologically in many ways. As long as the spike proteins tertiary structure has not changed to much from SARS to COVID, op could be correct. Emphasis on could.
- slver 5y agoEmphasis affirmed.
- autokad 5y agoI feel like talking about genes in % similarity seems to be useless.
- slver 5y agoThat was the point I was trying to drive home, more or less.
- bart__ 5y agoDo you have a source for your claim? Can't find anything about SARS, covid transimmunity.
- alien_ 5y agoThis should be relatively easy to verify, we have millions of people who have been infected early last year so we can see how many of them got reinfected recently with one of the more recent strains. If the immune response of the virus is close enough to what a vaccine gives and the mutation rate remains relatively constant, the number of reinfections would probably be a good indication of how much would we need subsequent shots, at least for a yearly renewal cycle. I wonder, are there any such studies?
- Dylan16807 5y agoIs that still a booster at that point?
- qzw 5y agoThe mRNA based technology underlying both the Pfizer and Moderna vaccines are expected to power a whole slew of applications in the future. I think these companies are quite happy that they just got an expedited, large scale demonstration of the effectiveness and safety of their tech, which will lead to many billions in future revenue.
- randomopining 5y agoYour opinion on this is worthless lol. Clearly the vaccines ended Covid in countries like Israel and Malta. Open your eyes.
- vengefulduck 5y agoI think you misunderstood, the GP is commenting on the Pfizer CEO saying that boosters will be required in 6 months which this paper seems to indicate won't be necessary.
- seunosewa 5y agoMight boosters still be required to provide immunity from new escape variants?
- nibsfive 5y agoNo. The variants are variants, not strains. It's based on gene deletes primarily. More Sneaky just means a bit less effective. Studies suggest about half as effective. So from 90% to 80% etc still highly effective.
- randomopining 5y agoMost people would pay $20 for improved effectiveness against newer variants, I would presume.
- takeda 5y agoMost people in 1st world countries (where $20 is not that much) would, but I like that it might not be needed. It's less hassle, and it also breaks all the assumptions were made by the anti vaccine misinformation.
- randomopining 5y agoAnti-vax, anti-mask crowd have been so wrong so many times over the last year. I doubt another huge L would change their minds. It's twilight zone level stuff.