7 ms·
However, taking 3 vitamins is almost entirely harmless.
by arghzzz 6y ago
However, taking 3 vitamins is almost entirely harmless.
- RL_Quine 6y agoMany are toxic (vitamin D included) in unsuitable amounts, that’s probably too strong of a statement.
- Femur 6y agoWhat amount of vitamin D is toxic?
- cj 6y agoThe study mentions 1,000 IU D3 dosage. A quick google turns up a rough figure of 60,000 IU "daily for multiple months" can become toxic. You're probably right, most things taken at 100x the normal dose for long period of time are toxic. (Water included)
- caseysoftware 6y agoThe largest dosage of D3 I can find on Amazon is 5000 IU in a 240 capsule bottle. To take 60000 IU, you'd have to take a dozen capsules daily, getting a new bottle every 20 days, probably multiple times. While possible, it does seem unlikely.
- jdahlin 6y agoThere are 50000 IU capsules readily available on many stores. Taking 100000 IU per day for months/years is not necessarily toxic, especially when reducing calcium intake.
- valarauko 6y agoI'm currently taking 60K IU D3. The dosage is 1 capsule a week, for 8 weeks, and the capsules come 4 to a pack. This is followed by a maintenance dosage of 1 60k capsule once a month.
- cj 6y agoIs this to treat a medical condition? I'm curious why an acute high dose would be preferable over a lower dose taken daily.
- gridlockd 6y agoSounds like he was diagnosed with a very low level of Vitamin D and got prescribed high dosage to get up to a healthy level quickly.
- valarauko 6y agoNo obvious medical condition, other than a vit D serum level of 15 ng/mL. Depending on who you ask, that's a deficiency. I'm personally less convinced. It's not quite an acute high dose. The body produces the equivalent of 10,000 IU per day in high sun exposure, so 60K per week tries to achieve that level. I believe the high dosage is simply convenience. The 2K IU daily dose is pretty common as well.
- youwouldntcar 6y agohas it had any impact on your mood?
- pavs 6y agoYou can bolous dose. Depending on the which country. It might be prescription only. I take 20,000 IU once a week, 1000 iu everyday. I have bought prescribed 60,000 IU in the past.
- caleb-allen 6y agoThere is an interesting video about a boy who did just that, by mistaking vitamin gummies for candy: https://www.youtube.com/watch?v=mZ6nREONy_4 https://www.youtube.com/watch?v=mZ6nREONy_4
- econcon 6y agoHigher ones can be found at a pharmacy
- woeirua 6y agoWater is lethal at far less than 100x the normal dose. Google hyponatremia. You can die from ingesting a gallon of water in a few minutes.
- LinuxBender 6y agoJust anecdotal observation, I have been taking 40,000 IU D3, 800mcg K2, 400mg Magnesium among other things, daily for 3+ years, no issue. I had to work my way up to that. I've been reversing calcium buildup in my vascular system to lower my CaC score. I know of many people doing the same thing, some longer than I have been. We are all doing good. I also stay well hydrated.
- olva22 6y agoSorry a bit off-topic, but what form of K2 and magnesium do you take? Can you point me to your protocol to reverse calcium buildup?
- LinuxBender 6y agoI can point you to some of the studies on calcium removal. [1] They don't create a well defined protocol, though doctors have formed their own. I take 600mcg K2 MK-7 and 200mcg of K2 MK-4. I alternate between Magnesium-lysinate-glycinate-chelate (bound to L-Lysine and L-Glycine) and Magnesium Citrate. Since I am listing papers I have to point out that I am not a doctor and this is not medical advise. This method has been working slowly for me and faster for others, likely due to epigenetic and environment factors. I take these things with fatty meals to allow D3 binding and absorption. [1] - https://www.google.com/search?hl=en&source=hp&biw=&bih=&q=site%3Anih.gov+D3+k2-mk-7+cac+score&btnG=Google+Search&iflsig=AINFCbYAAAAAXta4t_AKpjedNKVMNnd0s8TpAp-fGrAR&gbv=1 https://www.google.com/search?hl=en&source=hp&biw=&bih=&q=si...
- olva22 6y agoThanks so much! Really appreciate the info.
- youwouldntcar 6y ago800mcg K2 sounds extremely low for 40,000 IU D3, shouldn't you be taking 1800mcg K2?
- pen2l 6y agoYeah but come on, most everyone don't take it in unsuitable amounts just like they don't drink 6 gallons of water every day. Taking vitamin D for the average American will surely help in keeping good immunity, bone health, etc.
- nkingsy 6y agoD supplements as well as fish oil were thought promising until studies showed they did not really do what they were advertised to do in supplement form. https://www.acc.org/latest-in-cardiology/clinical-trials/2018/11/08/22/42/vital https://www.acc.org/latest-in-cardiology/clinical-trials/201...
- vanderZwan 6y agoHow typical that you get downvoted when you're one of the few here to actually cite a source for your claim. I do wonder though if this is an important caveat though: > among healthy participants. .. since the rest of the discussion resolves around adding supplements to fight shortages. If "healthy" implies not have said vitamin D shortage then that is still a useful study but doesn't disprove the thesis that taking supplements is probably a good idea.
- vanderZwan 6y agoIn general, yes, but not in this particular context: it is extremely common to have shortages of vitamin D, B12 and magnesium, and would take quite a bit of effort to overdose on them. (I have already been taking all three as supplements for the last year due to other research suggesting that having a shortage of them worsens ADHD symptoms)
- PudgePacket 6y agoEverything is toxic in unsuitable amounts, it's an empty statement that doesn't really serve any purpose and is impossible to discuss.
- GiorgioG 6y agoI took > 100,000IU for nearly 3 months (look up the Coimbra Protocol) with no ill effects. Avoid calcium like your life depends on it (even for months after stopping) and you'll likely be fine (I am not a doctor, this is not advice, just sharing my experience.)
- velox_io 6y agoB vitamins are the exception to the rule, most vitamins and minerals are toxic in high doses (like most things).
- MiroF 6y agoTherapy is also deadly in too high of quantities because if you're stuck in your therapists office and can't leave then you will starve to death or die of dehydration.
- Nursie 6y agoMany things are almost entirely harmless, but before recommending you do them anyway, you probably want to look at whether there's any point. Turning round in a circle three times before you leave the house is almost entirely harmless, and there's no evidence that doesn't stop you getting coronavirus...
- partyboat1586 6y agoTurning round in a circle three times also doesn't improve your health in general. Getting the right vitamins does improve your health.
- NickM 6y agoGetting too much of many vitamins can harm your health though.
- bobbydroptables 6y agoSo can too much air and water and literally anything else.
- MiroF 6y agoNot true of B12 at least. No known upper limit as of now.
- robocat 6y agoMostly correct. “Several studies have shown that megadoses of the vitamin can lead to outbreaks of acne and rosacea, a skin condition that causes redness and pus-filled bumps on the face. Yet, it should be noted that most of these studies focused on high-dose injections rather than oral supplements (5, 6, 7). There is also some evidence suggesting that high doses of B12 may lead to negative health outcomes in those with diabetes or kidney disease. One study found that people with diabetic nephropathy (loss of kidney function due to diabetes) experienced a more rapid decline in kidney function when supplemented with high-dose B vitamins, including 1 mg per day of B12. What’s more, the participants receiving the high-dose B vitamins had a greater risk of heart attack, stroke and death, compared to those receiving a placebo (8). Another study in pregnant women showed that extremely high B12 levels due to vitamin supplements increased the risk of autism spectrum disorder in their offspring (9).“ From: https://www.healthline.com/nutrition/too-much-vitamin-b12#helpful-or-harmful https://www.healthline.com/nutrition/too-much-vitamin-b12#he...
- MaxBarraclough 6y agoVitamin overdoses can be serious in the worst cases. https://en.wikipedia.org/wiki/Hypervitaminosis_A https://en.wikipedia.org/wiki/Hypervitaminosis_A https://en.wikipedia.org/wiki/Hypervitaminosis_D https://en.wikipedia.org/wiki/Hypervitaminosis_D
- jonplackett 6y agoNo one is suggesting an overdose though. In the amount in the study it is harmless.
- 0-_-0 6y agoThe study is not suggesting the administration of toxic amounts of vitamin D
- krageon 6y agoWhile toxic amounts of basically anything are bad, introducing random facts that have no bearing on what is discussed can mislead some readers into thinking you're making a point related to the topic at hand. While it may be unintentional, this is misleading and therefore not helpful.
- MaxBarraclough 6y agoLook at the context. I was responding to the implication that taking 3 vitamins is categorically safe. It is not.
- swader999 6y agoIn any normal sense it is safe.
- jerf 6y agoIf your definition of "safe" is so strict that it declares that's not safe, that's fine and your decision, but it's not a definition you can live by. You're not actually holding your actions in your life to that standard, because you can't be. It's fundamentally broken to do risk analysis without considering the possible benefits as well. Otherwise you end up with the answer to literally everything being "It could be harmful", with no countervailing possibilities, and your heuristic says "no" to everything, including doing nothing. You can't live that way.
- aaron695 6y agoNo, if you take the wrong 3 vitamins then your just harmed yourself by not taking the correct 3 or 2 or 5. Nicotine patches also have been said to help. Every study like this distracts from other studies, so it needs to be pushing towards correct.