12 ms·

Without heart disease, daily aspirin may be too risky

leetrout 7y ago
My neighbor took a daily baby aspirin and finally got tired of it and quit (much to his wife’s chagrin since it was her doing). He had a stroke 2 or 3 days later. The doctors say the aspirin was helping keep things at bay but I wondered if it was more like his body adjusted for the thinner blood.
- bitexploder 7y ago
  Yeah. You can’t just quit doing something like that without risk. I think suddenly thickening your blood is a risk factor for stroke. But maybe some plaque or something finally detached, no one can say for sure.
- pmiller2 7y ago
  That raises a question: how do you safely stop a daily low dose aspirin regimen? Are we talking about cutting tiny pills in half, then quarters, etc. over a period of a month?
  - mark-r 7y ago
    In my case it was easy: spend a month in the hospital. This was after a roller skating accident that gave me a huge brain hemorrhage. The hospital doctors went over all my prescriptions and changed nearly everything.
  - bd 7y ago
    When taking baby Aspirin and having anticipated bleeding (e.g. planned surgery or dental work), hematologist's advice was to start preparing about two weeks in advance: take pill every other day for about a week, then stop for another week. This paper tells The American College of Chest Physicians' recommendation is stopping 7-10 days in advance, in the clinical study they measured 96 hours (4 days) for "normalizetion of platelet reactivity": https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008770/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008770/ But please speak with your own doctor(s), your medical situation may differ.
siliconunit 7y ago
Taking 50mg before going to bed, for periods, (3-6months a year, during massive crunch time project deliveries), it helps me sleep better and be less tired, also it makes my dreams extremely vivid and more complex, is there any study on this? It is a constant aspect that I can reproduce steadily...
- lnanek2 7y ago
  There actually are studies showing pain killers work for mental pain and anxiety too, not just physical pain. E.g.: https://www.sciencedaily.com/releases/2013/04/130416085431.htm https://www.sciencedaily.com/releases/2013/04/130416085431.h... So I wouldn't be surprised if it helps you sleep, especially during stressful crunch time periods.
  - fencepost 7y ago
    It's more significant than that, if you dig in on "acetaminophen emotional response" you'll find a lot of coverage of it muting response both good and bad. Anecdatally, I know someone who takes a significant amount of Tylenol on a daily basis, and that person seems a lot more emotionally 'flat' than before that started.
JohnStrangeII 7y ago
Okay, I'm not a physician, but for me as a layman there does not seem to be anything new in the study described. Yes, not taking it without indication has always been the professional recommendation. Stopping Aspirin treatment can also increase the risk of a stroke, so the treatment shouldn't be stopped without medical supervision. I'm wondering whether there is any example of a medicament or artificial supplement that is recommended to be taken without indication. I've never heard of something like that. Vitamin supplements should be replaced by more healthy nutrition and maybe more fresh air, more sun, and doing some sport. If there is no diagnosed deficiency, then supplements have no benefits at all. Most of the "daily supplements" you can buy in a pharmacy can be replaced by occasionally drinking a glass of orange juice, eating a banana, or eating something with honey. I once went to the pharmacy when I had a cold and didn't check what they were giving to me very carefully. At home, I realized that I just bought some pills that contained traces of honey... at a price of 16 EUR!
- layoutIfNeeded 7y ago
  >more sun Pls no. Skin cancer is no joke.
  - unfunco 7y ago
    Nor are these damn rickets.
  - JohnStrangeII 7y ago
    What I mean is 20 minutes/day to get your Vitamin D levels right.
  - mrob 7y ago
    Sun exposure increases skin cancer risk, but skin cancer is in most cases easily treatable if caught early, and there's evidence that sun exposure reduces all cause mortality, e.g.: http://ar.iiarjournals.org/content/38/2/1173.long http://ar.iiarjournals.org/content/38/2/1173.long If this is a real causal link, the next important question is how much is attributable to vitamin D synthesis (which, assuming the localization of vitamin D in the skin isn't important, could theoretically be replaced by supplements), and how much is attributable to things that can't be supplemented, e.g. increased nitric oxide synthesis. See: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593895/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593895/
winchling 7y ago
What about taking it with recovery periods e.g. not at the weekends, or on alternate months? What would that do to the risk/benefit?
BuildTheRobots 7y ago
I wonder if there's any correlation between people who take daily/regular aspirin and vascular dementia in later life. My Grandpa swore by daily dosing but then also battled vascular and alzheimers. Is the increased risk in bleeds only whilst taking aspirin or does it persist afterwards at all?
baxtr 7y ago
“Keep your dietary cholesterol to less than 200 milligrams a day.“ [1] Cholesterol in one egg: 373 mg [google] Maybe, instead of taking a daily pill, a change in diet will do the trick? [1] https://www.nhlbi.nih.gov/files/docs/public/heart/chol_tlc.pdf https://www.nhlbi.nih.gov/files/docs/public/heart/chol_tlc.p... High blood cholesterol can affect anyone. It’s a serious condition that increases the risk for heart disease, the number one killer of Americans—women and men. The higher your blood cholesterol level, the greater your risk.
- deleted 7y ago
  [deleted]
- bitexploder 7y ago
  There still isn’t any good evidence that I have seen proving eggs increase blood cholesterol. I eat plenty and get my numbers checked every 6 months. Probably quit eating bad fats and excess carbs.
- CydeWeys 7y ago
  There hasn't been much if any correlation shown between dietary cholesterol and blood-level cholesterol for most people. Your digestive tract has no problems breaking cholesterol down and metabolizing it, and conversely, your liver has no problem making cholesterol. This makes sense, as cholesterol is vital for the proper functioning of your brain amongst other organs, so we can't rely on getting enough of it from our diet.
  - baxtr 7y ago
    Why is the NIH then saying you shouldn’t get more than 200mg per day?
    - CydeWeys 7y ago
      The linked report is from 2005. They are no longer making this blanket recommendation. As another commenter points out, that's about the cholesterol contained in one egg, and less than the amount of cholesterol in a typical portion of meat. It just doesn't make sense that our body would have so many issues handling something that's been so prevalent in our diet for millions of years, and that we're well-adapted to consume. We're omnivores, not herbivores, and animal products contain cholesterol. We can handle eating it.
juskrey 7y ago
People should just finally understand that there is no free lunch: any substance has side effects. Even water, depending on dosage.
- deleted 7y ago
  [deleted]
- melling 7y ago
  That would be great. At that point, we can all collectively decide that it’s a better idea to spend more on medical research. https://futurism.com/the-byte/doctors-autonomous-surgery-robot-heart https://futurism.com/the-byte/doctors-autonomous-surgery-rob... For example, deaths from cancer(s) and heart disease will drop dramatically in which decade? [ ] 2120 [ ] 2070 [ ] 2050 [ ] 2030 Pick one. It’s really just a matter of effort.
  - juskrey 7y ago
    Far better idea is to remove as much cancerous bureaucratic institutions as possible. Starting from those which promote dangerous massive top-down health advices and policies, especially which add this or that pill for non-emergency "preconditions".
- amelius 7y ago
  Reminds me of: https://www.dhmo.org/facts.html https://www.dhmo.org/facts.html
- Gibbon1 7y ago
  I read a doctor complain about the balkanization of medicine into specialties. Specialists will give advice that reduces problems in their specialty and not care if it causes problems not in their specialty. Example: Keep children out of the sun to reduce the chance of skin cancer. Result, sub clinical rickets and myopia.
eyeball 7y ago
325mg per day here. Great.
ashelmire 7y ago
This is a meta-analysis of 13 studies. The rate change is certainly real, but remember this wasn't a study targeting that characteristic. I also didn't read the studies mentioned, so I don't know what time frame the change appears over (is it over a patients lifetime? a year? who knows?). Also, all of the patients were Asian, which could also have some effect, and they were all lean. As far as I'm aware, these aren't characteristics of those who usually receive recommendations for regularly taking aspirin. Meanwhile, heart disease kills nearly a quarter of Americans. > Results The search identified 13 randomized clinical trials of low-dose aspirin use for primary prevention, enrolling 134 446 patients. Pooling the results from the random-effects model showed that low-dose aspirin, compared with control, was associated with an increased risk of any intracranial bleeding (8 trials; relative risk, 1.37; 95% CI, 1.13-1.66; 2 additional intracranial hemorrhages in 1000 people), with potentially the greatest relative risk increase for subdural or extradural hemorrhage (4 trials; relative risk, 1.53; 95% CI, 1.08-2.18) and less for intracerebral hemorrhage and subarachnoid hemorrhage. Patient baseline features associated with heightened risk of intracerebral hemorrhage with low-dose aspirin, compared with control, were Asian race/ethnicity and low body mass index. > Conclusions and Relevance Among people without symptomatic cardiovascular disease, use of low-dose aspirin was associated with an overall increased risk of intracranial hemorrhage, and heightened risk of intracerebral hemorrhage for those of Asian race/ethnicity or people with a low body mass index.
- kurthr 7y ago
  Thanks for the tldr! A meta-analysis that contains only Asians (Taiwanese) with low body mass... is not relevant to me, and frankly not particularly relevant to, "U.S. doctors have long advised adults who haven’t had a heart attack or stroke but are at high risk for these events to take a daily aspirin pill", the lead in to the article.
CryptoBanker 7y ago
What's the news? My friends and I have always been aware that daily ibuprofin/aspirin could cause serious blood clotting issues.
- cblum 7y ago
  Ibuprofen, yes. Aspirin, no. Aspirin is a blood thinner.
- Spooky23 7y ago
  Ibuprofen overuse screws up your kidneys. Aspirin prevents clotting and causes bleeding
DonHopkins 7y ago
I personally find the taste of aspirin to be delicious! Not steak or candy delicious, but more like tangy taco sauce delicious. So I chew them up and swish them around my mouth and rub them up against the inside of my lips with my tongue, to get the most effective rush and quickest headache relief. Does anybody else do that, or am I a mutant?
- homero 7y ago
  It's just like citric, malic or tataric acid
  - DonHopkins 7y ago
    Yes, that was what I was getting at: delicious like limes!
- GordonS 7y ago
  > to get the most effective rush You get a "rush" from... aspirin?
  - DonHopkins 7y ago
    It feels like suddenly not having a headache any more! I love it!
- amelius 7y ago
  Caution! https://www.ncbi.nlm.nih.gov/pubmed/15354902 https://www.ncbi.nlm.nih.gov/pubmed/15354902 Tooth erosion caused by chewing aspirin.
RickJWagner 7y ago
Ugh, this is terrible news. I have a family history of heart disease, so I've been taking a small aspirin daily as part of my doctor's recommendation. I've been trusting this to help increase my chances of avoiding a heart attack. I'm going to keep taking it. I don't think I'll even talk to the doctor about it.
- wolco 7y ago
  General medical advise that is true under certain conditions. Make sure starting/stopping makes sense for you.
- zatertip 7y ago
  Consult with your doctor about getting on a statin. And if you have a family history of heart disease, I'd guess you qualify for aspirin as primary prevention.
- tellak 7y ago
  There new guidelines in the US that still recommend aspirin based on cardiovascular risk. That aspirin increases the risk of bleeding is old news. The difficulty has been in quantifying the risk/benefit. You should consult with your doctor about your specific circumstance.
MarkMc 7y ago
It's strange that this article mentions the increased risk of internal bleeding but doesn't mention the reduced risk of cancer. Here's a study which suggests that if 1,000 people aged 60 took aspirin daily for 10 years then 3 more people would die from strokes, bleeding and ulcers, but 17 fewer people would die from cancer and heart attacks. If that's true, then the benefits of daily aspirin clearly outweighs the costs. https://scienceblog.cancerresearchuk.org/2014/08/06/aspirin-and-cancer-not-quite-but-nearly/ https://scienceblog.cancerresearchuk.org/2014/08/06/aspirin-...
- JoshMnem 7y ago
  > "If that's true, then the benefits of daily aspirin clearly outweighs the costs." Why add aspirin though? If you want to reduce the chance of cancer, eat less junk and more vegetables, legumes, and fruits.
  - insertnickname 7y ago
    Compliance is easier with aspirin than with eating well.
    - JoshMnem 7y ago
      Personal development isn't easy, but there is no pill that can replace a healthy lifestyle. I took the plunge into a strict, healthy diet 3 years ago and it eventually became easy.
  - firethief 7y ago
    Am I missing the reason these choices are mutually exclusive?
    - megous 7y ago
      Aspirin may be more effective if you eat badly. I'm not saying it is.
- dontbenebby 7y ago
rodmena 7y ago
I have two words: OH FUCK. I take 85 mg every night (and since I live in Iran, we don't have access to high quality drugs thanks to American Orange Guerilla: President Trump). Btw, the title is misleading, 0.2 percent is not too much, is it?
tzs 7y ago
Here's the entry at the NNT site for daily aspirin [1]. [1] http://www.thennt.com/nnt/aspirin-to-prevent-a-first-heart-attack-or-stroke-2/ http://www.thennt.com/nnt/aspirin-to-prevent-a-first-heart-a...
amelius 7y ago
Is it a good idea to take extra vitamin K with aspirin when taken long-term, since it opposes the blood-thinning effect?
aj7 7y ago
Whoa! Is this an 81mg, 325mg, or other dose? Anyone out there know?
Madmallard 7y ago
Drugs are artificial modifications of the body with metabolization that has not ever been evolved. They cause problems people can't really fix it seems. It is really tragic. Antibiotics are seeming more and more dangerous by the year with new research.
AceyMan 7y ago
My internal medicine MD warned me away from daily low-dose aspirin a few years ago when we discussed it during my annual physical. "Unless you have a matching diagnosis that calls for treatment it's not something you should take routinely," were his basic words. Thee most obvious concern that a layman could wrap their head around were bleeding complications. So I stopped.
known 7y ago
Without an abnormal https://en.wikipedia.org/wiki/Transthoracic_echocardiogram https://en.wikipedia.org/wiki/Transthoracic_echocardiogram diagnosis report we should not take Aspirin Otherwise https://www.everydayhealth.com/congestive-heart-failure/guide/treatment/ https://www.everydayhealth.com/congestive-heart-failure/guid...

My neighbor took a daily baby aspirin and finally got tired of it and quit (much to his wife’s chagrin since it was her doing). He had a stroke 2 or 3 days later. The doctors say the aspirin was helping keep things at bay but I wondered if it was more like his body adjusted for the thinner blood.

bitexploder 7y ago
Yeah. You can’t just quit doing something like that without risk. I think suddenly thickening your blood is a risk factor for stroke. But maybe some plaque or something finally detached, no one can say for sure.
pmiller2 7y ago
That raises a question: how do you safely stop a daily low dose aspirin regimen? Are we talking about cutting tiny pills in half, then quarters, etc. over a period of a month?
- mark-r 7y ago
  In my case it was easy: spend a month in the hospital. This was after a roller skating accident that gave me a huge brain hemorrhage. The hospital doctors went over all my prescriptions and changed nearly everything.
- bd 7y ago
  When taking baby Aspirin and having anticipated bleeding (e.g. planned surgery or dental work), hematologist's advice was to start preparing about two weeks in advance: take pill every other day for about a week, then stop for another week. This paper tells The American College of Chest Physicians' recommendation is stopping 7-10 days in advance, in the clinical study they measured 96 hours (4 days) for "normalizetion of platelet reactivity": https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008770/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008770/ But please speak with your own doctor(s), your medical situation may differ.

siliconunit 7y ago

Taking 50mg before going to bed, for periods, (3-6months a year, during massive crunch time project deliveries), it helps me sleep better and be less tired, also it makes my dreams extremely vivid and more complex, is there any study on this? It is a constant aspect that I can reproduce steadily...

lnanek2 7y ago
There actually are studies showing pain killers work for mental pain and anxiety too, not just physical pain. E.g.: https://www.sciencedaily.com/releases/2013/04/130416085431.htm https://www.sciencedaily.com/releases/2013/04/130416085431.h... So I wouldn't be surprised if it helps you sleep, especially during stressful crunch time periods.
- fencepost 7y ago
  It's more significant than that, if you dig in on "acetaminophen emotional response" you'll find a lot of coverage of it muting response both good and bad. Anecdatally, I know someone who takes a significant amount of Tylenol on a daily basis, and that person seems a lot more emotionally 'flat' than before that started.

JohnStrangeII 7y ago

Okay, I'm not a physician, but for me as a layman there does not seem to be anything new in the study described. Yes, not taking it without indication has always been the professional recommendation. Stopping Aspirin treatment can also increase the risk of a stroke, so the treatment shouldn't be stopped without medical supervision. I'm wondering whether there is any example of a medicament or artificial supplement that is recommended to be taken without indication. I've never heard of something like that. Vitamin supplements should be replaced by more healthy nutrition and maybe more fresh air, more sun, and doing some sport. If there is no diagnosed deficiency, then supplements have no benefits at all. Most of the "daily supplements" you can buy in a pharmacy can be replaced by occasionally drinking a glass of orange juice, eating a banana, or eating something with honey. I once went to the pharmacy when I had a cold and didn't check what they were giving to me very carefully. At home, I realized that I just bought some pills that contained traces of honey... at a price of 16 EUR!

layoutIfNeeded 7y ago
>more sun Pls no. Skin cancer is no joke.
- unfunco 7y ago
  Nor are these damn rickets.
- JohnStrangeII 7y ago
  What I mean is 20 minutes/day to get your Vitamin D levels right.
- mrob 7y ago
  Sun exposure increases skin cancer risk, but skin cancer is in most cases easily treatable if caught early, and there's evidence that sun exposure reduces all cause mortality, e.g.: http://ar.iiarjournals.org/content/38/2/1173.long http://ar.iiarjournals.org/content/38/2/1173.long If this is a real causal link, the next important question is how much is attributable to vitamin D synthesis (which, assuming the localization of vitamin D in the skin isn't important, could theoretically be replaced by supplements), and how much is attributable to things that can't be supplemented, e.g. increased nitric oxide synthesis. See: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593895/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593895/

winchling 7y ago

What about taking it with recovery periods e.g. not at the weekends, or on alternate months? What would that do to the risk/benefit?

BuildTheRobots 7y ago

I wonder if there's any correlation between people who take daily/regular aspirin and vascular dementia in later life. My Grandpa swore by daily dosing but then also battled vascular and alzheimers. Is the increased risk in bleeds only whilst taking aspirin or does it persist afterwards at all?

baxtr 7y ago

“Keep your dietary cholesterol to less than 200 milligrams a day.“ [1] Cholesterol in one egg: 373 mg [google] Maybe, instead of taking a daily pill, a change in diet will do the trick? [1] https://www.nhlbi.nih.gov/files/docs/public/heart/chol_tlc.pdf https://www.nhlbi.nih.gov/files/docs/public/heart/chol_tlc.p... High blood cholesterol can affect anyone. It’s a serious condition that increases the risk for heart disease, the number one killer of Americans—women and men. The higher your blood cholesterol level, the greater your risk.

deleted 7y ago
[deleted]
bitexploder 7y ago
There still isn’t any good evidence that I have seen proving eggs increase blood cholesterol. I eat plenty and get my numbers checked every 6 months. Probably quit eating bad fats and excess carbs.
CydeWeys 7y ago
There hasn't been much if any correlation shown between dietary cholesterol and blood-level cholesterol for most people. Your digestive tract has no problems breaking cholesterol down and metabolizing it, and conversely, your liver has no problem making cholesterol. This makes sense, as cholesterol is vital for the proper functioning of your brain amongst other organs, so we can't rely on getting enough of it from our diet.
- baxtr 7y ago
  Why is the NIH then saying you shouldn’t get more than 200mg per day?
  - CydeWeys 7y ago
    The linked report is from 2005. They are no longer making this blanket recommendation. As another commenter points out, that's about the cholesterol contained in one egg, and less than the amount of cholesterol in a typical portion of meat. It just doesn't make sense that our body would have so many issues handling something that's been so prevalent in our diet for millions of years, and that we're well-adapted to consume. We're omnivores, not herbivores, and animal products contain cholesterol. We can handle eating it.

juskrey 7y ago

People should just finally understand that there is no free lunch: any substance has side effects. Even water, depending on dosage.

deleted 7y ago
[deleted]
melling 7y ago
That would be great. At that point, we can all collectively decide that it’s a better idea to spend more on medical research. https://futurism.com/the-byte/doctors-autonomous-surgery-robot-heart https://futurism.com/the-byte/doctors-autonomous-surgery-rob... For example, deaths from cancer(s) and heart disease will drop dramatically in which decade? [ ] 2120 [ ] 2070 [ ] 2050 [ ] 2030 Pick one. It’s really just a matter of effort.
- juskrey 7y ago
  Far better idea is to remove as much cancerous bureaucratic institutions as possible. Starting from those which promote dangerous massive top-down health advices and policies, especially which add this or that pill for non-emergency "preconditions".
amelius 7y ago
Reminds me of: https://www.dhmo.org/facts.html https://www.dhmo.org/facts.html
Gibbon1 7y ago
I read a doctor complain about the balkanization of medicine into specialties. Specialists will give advice that reduces problems in their specialty and not care if it causes problems not in their specialty. Example: Keep children out of the sun to reduce the chance of skin cancer. Result, sub clinical rickets and myopia.

eyeball 7y ago

325mg per day here. Great.

ashelmire 7y ago

This is a meta-analysis of 13 studies. The rate change is certainly real, but remember this wasn't a study targeting that characteristic. I also didn't read the studies mentioned, so I don't know what time frame the change appears over (is it over a patients lifetime? a year? who knows?). Also, all of the patients were Asian, which could also have some effect, and they were all lean. As far as I'm aware, these aren't characteristics of those who usually receive recommendations for regularly taking aspirin. Meanwhile, heart disease kills nearly a quarter of Americans. > Results The search identified 13 randomized clinical trials of low-dose aspirin use for primary prevention, enrolling 134 446 patients. Pooling the results from the random-effects model showed that low-dose aspirin, compared with control, was associated with an increased risk of any intracranial bleeding (8 trials; relative risk, 1.37; 95% CI, 1.13-1.66; 2 additional intracranial hemorrhages in 1000 people), with potentially the greatest relative risk increase for subdural or extradural hemorrhage (4 trials; relative risk, 1.53; 95% CI, 1.08-2.18) and less for intracerebral hemorrhage and subarachnoid hemorrhage. Patient baseline features associated with heightened risk of intracerebral hemorrhage with low-dose aspirin, compared with control, were Asian race/ethnicity and low body mass index. > Conclusions and Relevance Among people without symptomatic cardiovascular disease, use of low-dose aspirin was associated with an overall increased risk of intracranial hemorrhage, and heightened risk of intracerebral hemorrhage for those of Asian race/ethnicity or people with a low body mass index.

kurthr 7y ago
Thanks for the tldr! A meta-analysis that contains only Asians (Taiwanese) with low body mass... is not relevant to me, and frankly not particularly relevant to, "U.S. doctors have long advised adults who haven’t had a heart attack or stroke but are at high risk for these events to take a daily aspirin pill", the lead in to the article.

CryptoBanker 7y ago

What's the news? My friends and I have always been aware that daily ibuprofin/aspirin could cause serious blood clotting issues.

cblum 7y ago
Ibuprofen, yes. Aspirin, no. Aspirin is a blood thinner.
Spooky23 7y ago
Ibuprofen overuse screws up your kidneys. Aspirin prevents clotting and causes bleeding

DonHopkins 7y ago

I personally find the taste of aspirin to be delicious! Not steak or candy delicious, but more like tangy taco sauce delicious. So I chew them up and swish them around my mouth and rub them up against the inside of my lips with my tongue, to get the most effective rush and quickest headache relief. Does anybody else do that, or am I a mutant?

homero 7y ago
It's just like citric, malic or tataric acid
- DonHopkins 7y ago
  Yes, that was what I was getting at: delicious like limes!
GordonS 7y ago
> to get the most effective rush You get a "rush" from... aspirin?
- DonHopkins 7y ago
  It feels like suddenly not having a headache any more! I love it!
amelius 7y ago
Caution! https://www.ncbi.nlm.nih.gov/pubmed/15354902 https://www.ncbi.nlm.nih.gov/pubmed/15354902 Tooth erosion caused by chewing aspirin.

RickJWagner 7y ago

Ugh, this is terrible news. I have a family history of heart disease, so I've been taking a small aspirin daily as part of my doctor's recommendation. I've been trusting this to help increase my chances of avoiding a heart attack. I'm going to keep taking it. I don't think I'll even talk to the doctor about it.

wolco 7y ago
General medical advise that is true under certain conditions. Make sure starting/stopping makes sense for you.
zatertip 7y ago
Consult with your doctor about getting on a statin. And if you have a family history of heart disease, I'd guess you qualify for aspirin as primary prevention.
tellak 7y ago
There new guidelines in the US that still recommend aspirin based on cardiovascular risk. That aspirin increases the risk of bleeding is old news. The difficulty has been in quantifying the risk/benefit. You should consult with your doctor about your specific circumstance.

MarkMc 7y ago

It's strange that this article mentions the increased risk of internal bleeding but doesn't mention the reduced risk of cancer. Here's a study which suggests that if 1,000 people aged 60 took aspirin daily for 10 years then 3 more people would die from strokes, bleeding and ulcers, but 17 fewer people would die from cancer and heart attacks. If that's true, then the benefits of daily aspirin clearly outweighs the costs. https://scienceblog.cancerresearchuk.org/2014/08/06/aspirin-and-cancer-not-quite-but-nearly/ https://scienceblog.cancerresearchuk.org/2014/08/06/aspirin-...

JoshMnem 7y ago
> "If that's true, then the benefits of daily aspirin clearly outweighs the costs." Why add aspirin though? If you want to reduce the chance of cancer, eat less junk and more vegetables, legumes, and fruits.
- insertnickname 7y ago
  Compliance is easier with aspirin than with eating well.
  - JoshMnem 7y ago
    Personal development isn't easy, but there is no pill that can replace a healthy lifestyle. I took the plunge into a strict, healthy diet 3 years ago and it eventually became easy.
- firethief 7y ago
  Am I missing the reason these choices are mutually exclusive?
  - megous 7y ago
    Aspirin may be more effective if you eat badly. I'm not saying it is.
dontbenebby 7y ago

rodmena 7y ago

I have two words: OH FUCK. I take 85 mg every night (and since I live in Iran, we don't have access to high quality drugs thanks to American Orange Guerilla: President Trump). Btw, the title is misleading, 0.2 percent is not too much, is it?

tzs 7y ago

Here's the entry at the NNT site for daily aspirin [1]. [1] http://www.thennt.com/nnt/aspirin-to-prevent-a-first-heart-attack-or-stroke-2/ http://www.thennt.com/nnt/aspirin-to-prevent-a-first-heart-a...

amelius 7y ago

Is it a good idea to take extra vitamin K with aspirin when taken long-term, since it opposes the blood-thinning effect?

aj7 7y ago

Whoa! Is this an 81mg, 325mg, or other dose? Anyone out there know?

Madmallard 7y ago

Drugs are artificial modifications of the body with metabolization that has not ever been evolved. They cause problems people can't really fix it seems. It is really tragic. Antibiotics are seeming more and more dangerous by the year with new research.

AceyMan 7y ago

My internal medicine MD warned me away from daily low-dose aspirin a few years ago when we discussed it during my annual physical. "Unless you have a matching diagnosis that calls for treatment it's not something you should take routinely," were his basic words. Thee most obvious concern that a layman could wrap their head around were bleeding complications. So I stopped.

known 7y ago

Without an abnormal https://en.wikipedia.org/wiki/Transthoracic_echocardiogram https://en.wikipedia.org/wiki/Transthoracic_echocardiogram diagnosis report we should not take Aspirin Otherwise https://www.everydayhealth.com/congestive-heart-failure/guide/treatment/ https://www.everydayhealth.com/congestive-heart-failure/guid...