xaa

26 ms·

181.
by xaa 12y ago
Go nuts. https://www.dropbox.com/s/2zdys9hzpr6a7ln/ioi140152.pdf?dl=0
182.
by xaa 12y ago
Sauna bathing is associated with reduced risk ;)
183.
by xaa 12y ago
Yes, yes they do. I think it is because of the following sequence of events: a) bioinformaticians are usually shitty programmers, therefore b) a lot of the tools are bad, at least from a programming perspective, therefore (?) c) I'll w
184.
by xaa 12y ago
> I reviewed one paper which said the algorithm was faster and more memory efficient than the previous version of itself. But with no numbers. The aforementioned colleague says he usually editorially rejects those. Actually another amusi
185.
by xaa 12y ago
Alas, alignment is not in my area of expertise, nor of the people I know directly. I'm a heavy user, but not a developer of aligners (except a toy one). You could consider contacting Cole Trapnell or someone well known for making a wid
186.
by xaa 12y ago
My colleague (an editor at Bioinformatics journal) and I were joking the other day about how every other paper title, especially about aligners, seems to include the word "fast" in it. This takes it to a new level. As a learning e
187.
by xaa 12y ago
I view the JVM choice as a pragmatic choice to encourage wider adoption rather than a technical choice. Possibly it eased implementation too having a high-quality GC, but overall the drawbacks are quite severe, because they outright preclud
188.
by xaa 12y ago
Obviously because it is quite reasonable to assume that standards of living partially cause gender distribution by making daycare affordable, allowing more paid leave, etc., whereas gender polarization would not be expected to be a strong e
189.
by xaa 12y ago
Thank you so much for this reference. The moment I grokked Clojure, I immediately thought "someone should port this to LLVM". The JVM is awful in a thousand ways, and it is quite surprising to me that Rich Hickey would devote so m
190.
by xaa 12y ago
> Sorry. The damage that a bad teacher can do outweighs much or all of the good that the good teachers can do. > If your kid would have 40 doctors throughout his life, only 2 or 3 of which were quacks, would that make you happy? I don
191.
by xaa 12y ago
> Longevity research is currently a career dead end. Ouch, that's my career ;) But the current trick to do longevity research in a way that will be funded is to point out how major diseases have age as a major risk factor, and that
192.
by xaa 12y ago
It was an interesting read for sure, and I appreciate it for what it is. Of course, this is HN, so we have to criticize ;) Vowpal Wabbit is a great project that implements approximate, streaming versions of a lot of basic machine learning a
193.
by xaa 12y ago
My nitpicking was more about how they were presented. If you are simply using a bloom filter to avoid random disk access on the database, then no, you haven't lost accuracy in your system-as-a-whole. Also, and I guess this is more fuzz
194.
by xaa 12y ago
It's good that the "Big Data" community is finally shifting the paradigm (back) to stream processing. I mean, it is the abstraction behind pipes, which were invented when data we now consider small was Big. Now if only someon
195.
by xaa 12y ago
> I think I might be below your threshold, though. No. At least for a huge fraction of the available jobs. What you have said, plus the very fact you are on this site, makes this almost certain. You need to realize what "incompetenc
196.
by xaa 12y ago
OK, then I misjudged your situation a bit, and in this case, your problem is likely not the code side of things, but the communication side. One thing is that you are obviously down on yourself. That is self-defeating and self-reinforcing,
197.
by xaa 12y ago
Having gone through this stage myself and now mentoring others going through the same thing, I think it is an inevitable part of learning to code. A few pieces of advice: - The first key is to keep trying -- it WILL get easier and become se
198.
by xaa 12y ago
I'm also interested in an answer to this question. Perl 6, as a feature set, looks awesome and I'd really consider replacing my use of Python with it, espcially because of the gradual typing and fast startup time (assuming Perl 6
199.
by xaa 12y ago
Yes, indeed, and because of this, I'd suggest you not rule out bioinformatics before talking to someone who does it. I'm a bioinformatician, I love it, and having both an M.D. and skill in programming would be a huge competitive a
200.
by xaa 12y ago
P(lose|can’t raise money)=low ?? Also, raising the number of Congresspeople would raise communication costs between them significantly, making it harder to coordinate on bills.
201.
by xaa 12y ago
Ouch. I can't speak for comics, as the only ones I've really enjoyed are Alan Moore comics which emphatically aren't suitable for children (Discworld is good, though), but plenty of sci-fi has high cultural value, IMO, in bot
202.
by xaa 12y ago
Very likely. I heard an two-way interview on NPR with the editor of the Washington Post, another editor from a prominent UK paper (either the Observer or Guardian, can't remember and can't find the episode, but both are members of
203.
by xaa 12y ago
My research institute has a 11.7T (for small animals). Although I must say, using MRI, even such a powerful one, for research is not as useful or cool as you'd expect since it takes so long to do one scan.
204.
by xaa 12y ago
Well, if SENS has the answer, the TFA has a $1M incentive for them to prove it, since this prize isn't about mechanism at all. I think the idea of focusing on understanding and slowing the accumulation of damage is partially based on t
205.
by xaa 12y ago
I honestly believe that if I want to transition later, I will be no worse off than a postdoc, and possibly better off. At my particular institution, I have known several who have transitioned (all older than me, and most who had done postdo
206.
by xaa 12y ago
Sort of. Yes, I do research at a university-equivalent (a nonprofit academic research institution). Someone else's grant funds my paycheck, but in practice, staff scientist is often a position which is intermediate in freedom between p
207.
by xaa 12y ago
I'm 27, skipped postdoc, and make $60K in a staff scientist position. I am able to get away with this because bioinformatics is in huge demand. At my institution this also does not preclude a later tenure-track position. Basically, you
208.
by xaa 12y ago
In many US schools, there is a similar system: gifted programs (in elementary), pre-AP (middle school), and AP (high school) segregate the "gifted" kids from the rest. I think it actually helps the gifted students. A lot. The best
209.
by xaa 12y ago
Well, if the problem were "not enough resources", then you would expect that calories consumed would positively correlate with lifespan. But of course, calorie restriction increases lifespan. This theory was rather popular before
210.
by xaa 12y ago
Calorie restriction still works in mice in cages with wheels (they often run 6 miles per night). I do not know if it has been tried with different numbers of mice per cage or in "enriched" environments. See for a very good review:

More ›