vedtopkar

5 ms·

1.
by vedtopkar 4mo ago
I use this one to tie my scrub pants and also to quickly tie my sterile gown when in the operating room. So handy!
2.
by vedtopkar 2y ago
I think it's the difference between suspicion of the pharmaceutical vs the pharmaceutical company. You can criticize the company without criticizing the treatment.
3.
by vedtopkar 2y ago
This seems to work: https://jamanetwork.com/journals/jama/fullarticle/2819356 Sadly no specifics about the 28 physicians they analyze.
4.
by vedtopkar 3y ago
In fact this is exactly how they set the price for these curative treatments. Gargantuan sums but hypothetically on average cheaper than the overall lifetime costs of living with the disease. Lots of recent debates on this in the world of H
5.
by vedtopkar 4y ago
I'll echo that it's a tremendous amount of work to appropriately format data and metadata for upload to a public repository. It's not as simple as just mass uploading raw data files. It's no surprise that people skirt ar
6.
by vedtopkar 4y ago
Another anecdote: I felt my mental health declining from being sucked into "academic Twitter", which frequently devolves into unnecessary soapboxing in response to preprints or journal articles. I unfollowed all humans and now onl
7.
by vedtopkar 5y ago
They speculate that the harmful component of e-readers is the blue-shifted illumination. I’d be curious if newer e-readers with temperature controllable backlights set to “warm” mitigates some of this sleep harm
8.
by vedtopkar 5y ago
It’s honestly so bad. No matter how hard I try, I find myself re-downloading TikTok or Reddit (Apollo) every month and then wasting away all my free time for a week or two before re-deleting them out of disgust. I truly don’t know what the
9.
by vedtopkar 5y ago
Curious as to why no one is recommending just paying for Google Workspace? $6/month for Google vs $5/month for Fastmail seems similar enough to avoid the hassle of transferring email servers.
10.
by vedtopkar 6y ago
I'm doing my PhD on topics related to mRNA and took a seminar class with Meselson in college. Really crazy how quickly our field has gone from obscure to mainstream this last year.
11.
by vedtopkar 6y ago
Sadly I don't know enough to give you a good answer. But I'm certain there are smart people working on it!
12.
by vedtopkar 6y ago
Sure, but I never said anything about clinical trials? Just bioequivalence, which is exactly what’s stated in your first link.
13.
by vedtopkar 6y ago
I don’t have the best answer for you, but there are a number of considerations apart from the synthesis of the active molecule itself. Delivery vehicle can alter the physiological impact of the active substantially, and so the overall “pack
14.
by vedtopkar 6y ago
This is cool, but what they're claiming is puzzling. Perhaps someone here can clarify. Making generic drugs is non-trivial. The medicinal chemistry may be decades old, but you still need to do trials to demonstrate efficacy equivalency
15.
by vedtopkar 6y ago
This sentiment is not unique to biomedicine. It's pretty often you see people finger elitism or capitalism for screwing people over because "I can make it myself." Ethically, you are more than welcome to experiment on yoursel
16.
by vedtopkar 6y ago
Oh man, this would be a dream...
17.
by vedtopkar 6y ago
Totally. "Older" physicians who happen to be tech literate definitely have an easier time transitioning.
18.
by vedtopkar 6y ago
Absolutely agree. The frustration with how much time is wasted is certainly universal. I would kill for a command line EHR, especially if I could edit notes in vim!
19.
by vedtopkar 6y ago
Having spoken to a lot of doctors during medical school, it really does feel like a generational thing. Physicians who were trained in the pre-EMR times have a really hard time transitioning. This is partially a UX design failure on the par
20.
by vedtopkar 6y ago
This is very interesting, will check it out. I really just need a reference capability.
21.
by vedtopkar 6y ago
Since these systems have been coming up so much on HN, I have to ask: are there any such softwares that play nicely with images, PDFs, and Word/Excel docs? I've been trying out Devon think and it's pretty good, but I'd p
22.
by vedtopkar 7y ago
This coverage is incredibly disingenuous. It's been known for a long time that base stacking is the dominant force in keeping a double helix together. Literally the first sentence of the abstract is "Hydrophobic base stacking is a
23.
by vedtopkar 7y ago
I have often joked that if I could eat Saag for every meal for the rest of my life I would. This exactly scratches my itch. Not even trying to be funny, this is exactly the type of service I have always wanted (down to the choose-your-pro
24.
by vedtopkar 7y ago
This is absolutely the right way to go. I'm on the market for a new car for the first time in a long time and the terrible UX decisions car makers are implementing is quite shocking.
25.
by vedtopkar 8y ago
Do you have a source for this? This may be true in other fields but most genome editing industry work is almost certainly done stateside.
26.
by vedtopkar 8y ago
As a grad student that has started and re-started writing a textbook for a couple of years, this is super inspiring! I love hearing about clever LaTeX tooling too.
27.
by vedtopkar 8y ago
Amazing and very well deserved! Checkpoint blockade drugs are in their nascency, and though they aren't a silver bullet, they can be incredibly effective nonetheless. A large number of people will be saved from cancer (and maybe some o
28.
by vedtopkar 8y ago
It's shocking to me that something so critical to the criminal justice system is not more tightly regulated nor monitored continuously for sensitivity/specificity.
29.
by vedtopkar 8y ago
I was an Evernote loyalist in the early days of the company, but eventually the apps got too sluggish and too complicated. The product started as a nice interface that got out of your way, but that went out the door as they tried to scale a
30.
by vedtopkar 8y ago
Thank goodness. The lack of 3rd party password manager integration was infuriating. Glad LastPass is usable natively.

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