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tsbischof
searching PlanetScale…
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31.
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by
tsbischof
4y ago
Part of the in-person experience is the opportunity for people to correct mistakes in communication. Many people are not effective writers, and so pushing for async or writing-heavy communication is difficult at best. Having one-on-ones by
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tsbischof
4y ago
I want people to be around each other enough that they are comfortable interacting. Some of my most painful experiences in management come from having to mediate a low-level dispute between people who work together but never interact on an
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tsbischof
4y ago
I worked at LBNL, at the Molecular Foundry. The day to day was a mix of typical nanoscience work (chemical synthesis, electron microscopy, etc) and work in support of the user facility. In my case that involved consulting on projects involv
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by
tsbischof
4y ago
Hard disagree on dropping quals. Quals were one of the only times where we were forced challenged to reexamine our ideas from a reasonably outside perspective, both to see that we actually knew the material and that we could work outside ou
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tsbischof
4y ago
Exactly, the PhD is a kind of participation trophy at some point. Quals are the last simple way to decide that someone will not get a PhD.
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tsbischof
4y ago
I recently had to dig into this. Federalism is wild: https://www.paycor.com/resource-center/articles/pto-payout-l...
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tsbischof
4y ago
I am glad to chat, my contact is my username at Gmail. I have broad experience in chemistry and materials science, and can at least help you get going in the right direction.
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tsbischof
4y ago
Not all Python users run containers, especially in the sciences. When you are teaching basics of data manipulation to people that have barely touched any programming language before, getting people to grok even virtual environments is not t
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tsbischof
4y ago
Part of the issue is that there is "no cost" to changing something in the software stack, while there are very tangible costs and barrier to entry to modifying a physical structure. This tends towards a more conservative culture,
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tsbischof
4y ago
Any particular issues? I am most opposed to the rigid 30-day cycles and the need to spend one just to get on the agenda. But in terms of the questions asked and the due diligence required, I have not found our IRBs to be onerous
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tsbischof
4y ago
For such a large effect it is quite possible to implement an adaptive trial design with unbalanced arms and interim analysis for efficacy. But you have to ask for this, the FDA will not necessarily suggest it directly.
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tsbischof
4y ago
It matters how it is perceived. If everyone involved sees a company firing a bad employee, then good. But if I were in that situation, I would see a company that decided to be greedy and did not care about the sacrifices you made for them.
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tsbischof
4y ago
Maybe? Weeder courses in CS based on SICP have similar dropout rates, and the push towards making the curriculum easier causes endless hand-wringing. We could argue that organic chemistry is less central to medicine than recursion and funct
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tsbischof
4y ago
Part of it is to ensure that your medical students are not terrified by "chemicals". Plus, doing organic chemistry instills into you the idea that reactions may not be pure, and that enantiomers are both real and potentially probl
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tsbischof
4y ago
Duplication of work prior to publication is standard in many experimental fields, like synthetic chemistry. In some cases the cost of an experiment is high enough to be a problem, but conductivity measurements are not really that exotic.
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tsbischof
4y ago
A 256-byte music demo: https://linusakesson.net/scene/a-mind-is-born/
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tsbischof
4y ago
No, from the perspective that it has allowed me to take on interesting projects that were otherwise impossible. In my case, by linking tools from different fields (spectroscopy, computer vision, chemistry, medicine, human systems hacking, .
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tsbischof
4y ago
Somewhat. At this point nano, 2D materials, topological materials, and other buzzwords of the past are either mainstream or dying. AI/ML for automated experiment design in high-throughput screening is the new hot stuff in experimental
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tsbischof
4y ago
https://en.m.wikipedia.org/wiki/Suicide_of_Jason_Altom One of three in a short period
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tsbischof
4y ago
You can traverse citations to that paper, looking for anything which actually talks about those results. There are some tools which do this. scite.ai has proven okay for quickly finding some of these citations, sometimes. Nothing beats manu
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tsbischof
4y ago
Depends on the field a bit, but my general process involves using a few questions to signal one way or the other. 1. What are the actual claims made by the authors? That is, what do they claim to have found in the study? If you cannot find
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tsbischof
5y ago
US National Labs (e.g. LBNL) can easily top 200%, based on what my colleagues told me at the time. I never applied for funding myself while there, so I cannot directly confirm the actual figures.
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tsbischof
5y ago
It's also about the issue that people will bias against generating the "difficult" data, even if only subconsciously. Real-world validation is essential to reveal whether you have actually worked through the full phase space.
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tsbischof
5y ago
It really should be on some form of balance sheet, in the form of "costs to implement new feature" (debt gets repaid in part by the next customer) or "costs to maintain" (ongoing interest payments that come out of overhe
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tsbischof
5y ago
Out of curiosity, what business model were they trying? A few years back we were looking into virtual trial site companies (e.g. Science 37), and the pitch seemed to make sense at the time (focus on studies which require minimal site visits
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tsbischof
5y ago
There is a lot less fakery in science than poorly-designed studies, misleading endpoints, underdocumented or incorrectly documented methods, and cargo-culting. The success of the process comes from having a good filtration process to sift t
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tsbischof
5y ago
In principle, submission is viable at many venues. PNAS has a few mechanisms for having established authors endorse your submission, for example. The main challenge is going to be the appearance of credibility to get past the starting point
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tsbischof
5y ago
Part of the challenge is the reputation issue. Academics want to publish where there is prestige, which means there has to be a perception of the venue as good. This typically either comes from reasonable gatekeeping and high-quality peers
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tsbischof
5y ago
Fix the service problem of actually being able to find films. Back in the day, Netflix's DVD library was close enough to complete that there was little need to look elsewhere, and their streaming selection was not terrible when it laun
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tsbischof
5y ago
What you miss out on is anything to do with your geographic community. Try looking for sources of local journalism like alt weeklies and zines based in your area. These tend to be published less often and curate for long-running issues rath
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