tsbischof

10 ms·

61.
by tsbischof 5y ago
For the article on Euler's conjecture, I am aware of this paper and that it serves as a sufficient proof of work for publication. It includes context for its purpose by citation, and the methods for verification were well-established.
62.
by tsbischof 5y ago
What do you see as the fundamental point of scientific communication? In your counterpoints you narrow in on papers being a means of communicating concepts or proof of work. In this view, showing the process itself is pointless or at least
63.
by tsbischof 5y ago
Solving this problem means providing a workable solution to the people in power, which in this case is homeowners. Can you find a solution which lets them keep their financial gains but also shifts the status quo? If not, they will fight yo
64.
by tsbischof 5y ago
The governing body and related stakeholders care at varying levels. For government-sponsored research, the primary metrics are publications, impact factor, number and prestige of collaborations, diversity of staff, and velocity of money (se
65.
by tsbischof 5y ago
The institution as a whole may have the incentive, which plays out on a 5-10 year timescale. Funding agencies in principle care, but no individuals are rewarded based on the results on this timescale. Industry, venture capital, and the like
66.
by tsbischof 5y ago
The equipment can be affordable depending on how you structure things. For example, there are opportunities like the Molecular Foundry user program [1] which provide grants for the costs of running experiments on expensive machinery. The ma
67.
by tsbischof 5y ago
I would be glad to have funding explicitly set towards appropriate and open documentation of the actual protocols, equipment, and materials, plus a combined effort to enhance these reporting requirements by the journal. There has to be a ba
68.
by tsbischof 5y ago
Part of this is being addressed through increased reporting requirements for data, software, analysis pipelines, pre-registered protocols, and the like. This has led anecedotally to some improvements in quality, and at minimum it makes init
69.
by tsbischof 5y ago
It is worse than nothing, because incorrect positive results and non-published negative results lead people to waste years of their lives building off something which is not true.
70.
by tsbischof 5y ago
> What can help make the literature more accessible? Publishing code and data associated with figures. A significant amount of the confusion about the literature comes from the difference between the documentation laid out in a paper and
71.
by tsbischof 5y ago
I have been on both sides of this. I worked for a time at a startup with decent salary in a generalist role, such that sometimes I did things directly related to my skillsets and interests, and other times got to pick up entirely new skills
72.
by tsbischof 5y ago
The challenge is that there are two directions for the knowledge retrieval: top-down and bottom-up. The "problem" here is that failure to learn from past, well-characterized solutions means we will be forced to revisit problems ex
73.
by tsbischof 5y ago
Pick a reputable company like Vanguard and sift through their categories of funds (index, sector, bonds, REITs, etc). Each will come with its own risk profile and past returns, so from there filter down into an investment thesis. Think Sili
74.
by tsbischof 5y ago
It depends on your relationship to work, relative to your outside life. The PhD in a good institution is essentially semi-supervised playing, where you are given access to resources and people to come up with and answer interesting question
75.
by tsbischof 5y ago
It could be as simple as checking tax records: in Germany, tithing is incorporated directly into tax declarations and payroll systems.
76.
by tsbischof 5y ago
In practice it generally comes down to demonstratable utility more than direct concerns about animal well-being. At the most basic level, if you can learn a useful lesson from subjecting an animal to whatever conditions, then the work is ge
77.
by tsbischof 5y ago
You do not cut out animal research but you push for a clearer path to safely start research in humans. Instead of repeated and overlapping pre-clinical studies, focus on designing studies to move as rapidly into humans as possible while ret
78.
by tsbischof 5y ago
Much of the problem comes from the fact that there is insufficient incentive for the studies to be effective in the first place. The sample size issue is real and often justified due to a lack of resources, but this results in minimum publi
79.
by tsbischof 5y ago
Independent verification is not always performed for 510k submissions, but yes that would be ideal
80.
by tsbischof 5y ago
I would be curious to see anything which lays out the specific claims and the evidence or justification used. For example, do you claim to detect malignant moles and if so what tests have you performed to demonstrate this. The language vari
81.
by tsbischof 5y ago
Could you provide a link to evidence obtained using your own device? Or perhaps a description of the tests you performed to determine substantial equivalence to the predicate devices?
82.
by tsbischof 5y ago
Can you clarify what you mean by certificates? Do you intend to link to approval documentation from a 510k clearance?
83.
by tsbischof 5y ago
This is an important question, and something we have considered when building our group. My background is largely in experimental physical sciences, and one of the vanity metrics in my fields is publication in a Nature- or Science-family jo
84.
by tsbischof 5y ago
I am helping lead the first research group at a recently-founded institute in Germany. What is the mission of your institute? Is this a collection of individuals doing their own research, or a group of collaborators working towards a shared