tomlue

7 ms·

31.
by tomlue 2y ago
I know you're coming from a good place, but the 'most people I meet don't understand this' line about statistics is quite arrogant. Most people you meet are fully capable of understanding statistics; you should do a bett
32.
by tomlue 2y ago
everybody has to start somewhere...
33.
by tomlue 2y ago
This isn't exactly what you are saying, but I have noticed that students basically 'overfit' the training data on multiple-choice tests. A nice use of LLMs might be to rewrite these questions on the fly so they test the same
34.
by tomlue 2y ago
This happened to me in a grant application. We had written a web application that did a homomorphic encryption based calculation of molecular weight to demonstrate that HE could be used to build federated learning models for chemical librar
35.
by tomlue 2y ago
wouldn't this cause issues with dna repair?
36.
by tomlue 2y ago
Epigenetic modifications, such as methylation, are made to DNA by specific proteins. These modifications alter the transcription process from DNA to RNA, which in turn affects protein expression. This includes the expression of the proteins
37.
by tomlue 2y ago
I used to feel this way too. It turns out the mirror test is not a good measure. Hard metrics are much better. Weight alone isn't the best, but it is a good place to start.
38.
by tomlue 3y ago
I made the habitbreaker chrome extension on this principle. It just blocks user selected websites for 30 seconds before loading. https://chromewebstore.google.com/detail/habitbreaker/kgioba... The idea is just to
39.
by tomlue 3y ago
so strongly agree. Grant writing is another good example of this. So much nonsense writing that just wastes everyone's time.
40.
by tomlue 3y ago
somebody write a textbook chunker that generates context from textbooks for LLMs to build anki cards please. Extra credit if you build a new anki that dynamically generates cards with different text and the same meaning to prevent answer me
41.
by tomlue 3y ago
agree so much. Projects that aim to build a data resource and then let AI use that resource are missing the point. The AI is the data resource. Some projects claim that knowledge graphs or other data assets can help the AI retrieve 'tr
42.
by tomlue 3y ago
In my experience boot strapping a startup, RDS is really expensive. Definitely a nice thing, but if you're a one person show trying to get to ramen profitable, RDS might not really make sense. If you are VC backed then go ahead!
43.
by tomlue 3y ago
So what will happen to junior developers and those developers whose code is mostly just plumbing?
44.
by tomlue 3y ago
This is so weird to me. Have you been using the tool? Have you asked it to review code yet? Just because it gets stuff wrong sometimes doesn't mean it isn't extremely useful.
45.
by tomlue 3y ago
I would not get overly focused on this use-case. It is more difficult to think of use-cases that won't get disrupted than those that will.
46.
by tomlue 3y ago
If the ‘tacit’ knowledge can be discovered in code, docs, email, slack, recorded conversations, etc then LLMs can find it and integrate it in its responses. This makes you easier to replace
47.
by tomlue 3y ago
Yes they will, a more capable chatgpt will do more than give you code to copy/paste, it will directly interact with your infrastructure, git repositories, etc. Even if it didn't, the capacity for a developer to learn all the frame
48.
by tomlue 3y ago
One very common task we have is writing and maintaining ETL scripts. This was never a particularly difficult task, just time consuming and normalized enough that I could outsource it. It's not that chatgpt can do the whole task, it&#x2
49.
by tomlue 3y ago
Some developers derive career stability by being the only person who understands a complex system at a company. This 'trick' has been undercut in a huge way. It is much easier for another dev to understand your complex system now,
50.
by tomlue 3y ago
Many companies that sell applications realize that chatgpt can easily replace their value prop. Even if it doesn't get 100% of the way there, people still much prefer to have less tools. A very large, difficult to comprehend, shakeup i
51.
by tomlue 3y ago
There are a lot of developers in denial here. I write code for scientific applications. I used to hire/contract out some work to other devs. In the last 6 months I haven't needed to hire anybody else, doing so would have been a wa
52.
by tomlue 4y ago
mostly agree. Though I wouldn't underestimate the tech and engineering work behind OpenAI. That microsoft partnership is no joke.
53.
by tomlue 4y ago
I'm a fan of OpenAI, but this is nonsense. All of human existence is mostly other people's ideas. Among a ridiculously huge list of other things, OpenAI benefits from the mountains of labor that made scalable neural networks possi
54.
by tomlue 4y ago
I think we’re doing the same thing? Want to work together? Some documentation https://docs.biobricks.ai A LinkedIn post https://www.linkedin.com/posts/tomluechtefeld_bioinformatics...
55.
by tomlue 4y ago
yeah +1 on this, seeing a lot of weird posts where people claim chatgpt screwed something up, and the prompt is all wrong or it is just a special case that will be solved eventually. The citation thing is a good example of this, just becaus
56.
by tomlue 4y ago
Article claims that chatgpt is overly sensitive to queries eg -gate suffix and come lad vs cum laude. This seems like a weak argument based on a temporary shortcoming. Any NLP methods search engines use for word meanings should be trivially
57.
by tomlue 4y ago
wow, starting to feel like papers are not a good metric for scientific progress. Who would've thought...
58.
by tomlue 4y ago
I don't know what you do for your work, but I suspect you haven't used chatgpt/copilot/etc enough to see the benefits. Do you think tab-autocompletion is useful? AI assistants can do that on steroids. Do you ever use exa
59.
by tomlue 4y ago
I don't work at a giant company, but I'm curious: > Anyone that has worked on large, complex system knows that the margin of error in uptime and downtime is often whether the right person is within arms’ reach of their laptop.
60.
by tomlue 4y ago
sometimes other people know what you want better than you do.

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