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tominous
searching PlanetScale…
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19 ms
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121.
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by
tominous
10y ago
Video and transcript are here: http://www.abc.net.au/tv/qanda/txt/s4499754.htm It's rare to see such a civil debate on this issue. I was impressed with everyone except for Shadow Minister Linda Burney wh
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by
tominous
10y ago
This could just as easily be about the perils of knowing how to look up symptoms on the web. If you're reading Hacker News you're probably used to reading fast, integrating new knowledge into a mental model and applying it all to
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Royal Caribbean Voom Internet Service Review
(blogs.harvard.edu)
1 points
by
tominous
10y ago
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0 comments
124.
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I Love Go; I Hate Go
(dtrace.org)
279 points
by
tominous
10y ago
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316 comments
125.
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by
tominous
10y ago
The problem with current immunotherapies is that they can trigger a wide range of auto-immune side effects: skin, lungs, gastrointestinal, thyroid, pituitary, liver, and more. Each dose is like spinning a roulette wheel and hoping it lands
126.
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by
tominous
10y ago
I don't see how public spending is immune to speculation, failed products, compliance and procurement costs! The rest are features, not bugs: * failed businesses free up resources for more productive activity * sales provide a feedback
127.
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by
tominous
10y ago
That seems like only a partial solution. How do you allocate the resources efficiently where they are needed most? How do you avoid waste? How do you avoid kickbacks and corruption and pork-barelling? How do you minimise administrative cost
128.
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by
tominous
10y ago
/...they needed to modify the molecule.. because the initial patent on rapamycin expired in 1992. The company would need a novel compound to market it in oncology./ So they had a good drug candidate already but needed to tweak it
129.
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by
tominous
10y ago
Phones turn off wifi whenever they can to save battery life. For example, Apple: "Notifications use Wi-Fi only when a cellular connection is unavailable." [1] [1] https://support.apple.com/HT201925
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by
tominous
10y ago
It's impossible to know. There are examples like John Nash where there is apparently a very good outcome, so I wouldn't lose hope. However, I would be concerned about long term physical changes from both the disease and the existi
131.
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by
tominous
10y ago
For the last few years I've been keeping an eye on Geneuro [1]. They're trialling a HERV-W antibody on the theory that this endogenous retrovirus triggers an immune reaction in the brain that causes multiple sclerosis. Schizophren
132.
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by
tominous
10y ago
Here's the secret: motivation only kicks in AFTER you start doing something. If you're waiting around for motivation to come out of the blue you'll be disappointed. So just start doing something. Choose one that appeals to yo
133.
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by
tominous
10y ago
The type of germs that kids share with each other are different to what you can pick up from the dirt. I suspect (though I would love to find evidence) that upper respiratory infections are far more common today than they were in the past.
134.
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by
tominous
10y ago
We had a yearly competition like that at school. The "winner" was always someone who put all their money in one penny stock and got lucky. A better approach is to reward the portfolio with the highest Sharpe ratio, but even that i
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by
tominous
10y ago
For anyone on mobile who is confused, try viewing in desktop mode.
136.
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by
tominous
10y ago
I used to work in an office which used fanless thin clients instead of normal desktop PCs. It was fantastic. Since then, normal offices filled with desktop fans have seemed almost painful to my ears. It makes a real difference by the end of
137.
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by
tominous
10y ago
One trick is to choose a scapegoat food that you don't care too much about, preferably something novel (e.g. strong liquorice might work). This has been shown to reduce the risk of aversion to normal food. [1] [1] http://www
138.
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by
tominous
10y ago
You could also say the next big tech startup will come from a random town around the world instead of Silicon Valley. But somehow the concentration of capital, expertise and opportunity in one place has a multiplier effect that makes Silico
139.
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by
tominous
10y ago
It's an interesting idea in theory but how do you ensure that money is well spent? It reminds me of the Australian government's "free insulation" scheme where a lot of money was poured into an industry very quickly. Resu
140.
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by
tominous
10y ago
The blog says that HNK (the purported antidepressant) is a known metabolite of ketamine, but then claims: > However, getting regulatory approval for such a study, which would technically (as far as I know) be a first-in-man trial of HNK,
141.
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by
tominous
11y ago
I feel the author's pain. I had a short consulting gig recently where I was asked to speed up a simulation job written in Python by a mechanical engineer. Smart guy but not a programmer, so the script was full of global variables, side
142.
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by
tominous
11y ago
Maybe I'm old-fashioned but if I was affected by this issue (and it had persisted for so long) I would set up an SMTP server and an appropriate MX record, then demonstrate using mail logs or port snooping that this was definitely not a
143.
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by
tominous
11y ago
Apologies to everyone for the ad-hominem flame-fest I seem to have triggered. I would have preferred this to stay on topic. jere, you do make a good point that there is more to it than just having free time and energy. e.g. There is also th
144.
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by
tominous
11y ago
Agreed, I have added a brief summary so others can avoid reading it if it's too much for their stomach :)
145.
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by
tominous
11y ago
Eric Raymond had an interesting take on the link between autism and exceptional achievement (if you can get past his ego). http://esr.ibiblio.org/?p=7060 In short, the time and energy normally spent on social interaction in
146.
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by
tominous
11y ago
That makes no sense. With about 40 million residents, the government of California would need to have approximately 1.6 million CPU cores dedicated to Oracle before named-user worked out cheaper than per-core licensing. Either that or there
147.
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by
tominous
11y ago
I'm not trying to minimise the real-world impact of research! I guess I'm saying in some fields (e.g. IT, and startups in particular) there is much tighter feedback between ability+effort and real-world results. I can imagine two
148.
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by
tominous
11y ago
When I was a student (undergrad and postgrad) I liked the constant judgement and competition. It can be quite addictive if you're good at it. Even the subjective assessments where half the game is figuring out and playing to the lectur
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by
tominous
11y ago
In my experience it's impossible to enter "flow" in a task unless I've practised to a certain level of automaticity. After that it becomes effortless and very rewarding. It's not so much about memorising facts for r
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by
tominous
11y ago
There are three key arguments in the article: homework saps intrinsic motivation to learn, harms relationships at home, and has an opportunity cost in sleep, rest and play. It all makes a lot of sense to me, but I have one thought. In many
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