sungam

10 ms·

91.
by sungam 5y ago
Whilst this might be true in general melanoma does respond particularly well to immunotherapy with 5 year survival rates in excess of 50% for advanced (metastatic) disease and a subset of patients effectively cured.
92.
by sungam 5y ago
This is possible at Cambridge and certain other universities for graduates of those universities: https://en.wikipedia.org/wiki/Doctor_of_Philosophy_by_public...
93.
by sungam 5y ago
Brian May started a PhD in astrophysics at Imperial college in the 70s and dropped out when Queen took off. He then re-registered in 2006 and completed so it was clearly possible at that time.
94.
by sungam 5y ago
Dermatologist, Mohs surgeon and clinical academic. I do lead research related to AI though so there is some relevance!
95.
by sungam 6y ago
13 years for me!
96.
by sungam 6y ago
The number of Dermatologists trained in the UK is entirely decided (and paid for) by central government. UK Dermatologists have for many years highlighted the need for training of more consultants.
97.
by sungam 6y ago
Yes this is the idea of mole mapping and there are 3D whole body photo imaging systems available for this with automated detection of changing lesions. It's harder to do on a smart phone but maybe possible.
98.
by sungam 6y ago
Situation may be slightly different in the NHS (national health service) where there is an overwhelming number of referrals from general practitioners for suspected skin cancer most of which turn out to be benign. As a consequence there is
99.
by sungam 6y ago
I am a dermatologist, AI researcher and co-founder of an AI startup (skinsmart.ai) and I would agree with you regarding the utility of AI in making an accurate diagnosis of melanoma. I don't think it has a significant role it play in t
100.
by sungam 6y ago
I have for many years (since nearly the beginning).
101.
by sungam 6y ago
A large proportion of the UK had milk delivered by electric vehicles 'milk floats' when I was a child in the 1980s... https://en.m.wikipedia.org/wiki/Milk_float
102.
by sungam 6y ago
Interesting project and I am sure that AI will come to play an important role in radiology in the future. However classifying CT scans for the diagnosis of covid-19 is very straightforward for even trainee radiologists and performing the sc
103.
Ask HN: Examples of Good Landing Pages?
1 points by sungam 6y ago|0 comments
104.
by sungam 6y ago
Typing this on my 2011 MBA which has been used a similar amount. Screen replaced during warranty and keyboard replaced subsequently but working fine!
105.
by sungam 6y ago
Interestingly the cessation of Arrow development presented a huge opportunity for the Apollo program which actively recruited these highly trained engineers for the moon landings (this is discussed in detail in Charles Murray's fascina
106.
by sungam 6y ago
If you have not already read it I would highly recommend Feynman's QED: The strange nature of light and matter - I am certainly not a mathematician or physicist but Feynman has a genius for communicating to the layman at a level that f
107.
by sungam 6y ago
I am interested in high resolution 3D mapping of skin surface e.g. for facial scar revision etc - what is the best technology available for this either research or commercial?
108.
by sungam 6y ago
We also looked at this for Dermatology with similar conclusions https://onlinelibrary.wiley.com/doi/full/10.1111/bjd.18880
109.
by sungam 7y ago
I agree that 3d printing is potentially of value for tissue engineering, however in this case the printed tissue is functionally no different from a full thickness skin graft which is used routinely for reconstruction of nasal defects and h
110.
by sungam 8y ago
Could it not be that the lifespan is just significantly longer than the observation period? If we looked at human mortality in a sample of a few thousand individuals over the first 30 years of life it would also appear rather flat.
111.
by sungam 9y ago
Conda is the anaconda python distribution widely used for machine learning and numerical computing.
112.
by sungam 9y ago
I would be interested to know to what extent the prediction of cardiovascular risk goes beyond a linear combination of the other factors such as hypertension, diabetes, age. I.e. if we just prediction these variables with the network then r
113.
by sungam 9y ago
This is a very interesting approach. Clearly a lot more work to do but the robust prediction of protein structure from sequence would be an absolute game changer for biomedical science so I hope that this opens up new strategies.
114.
by sungam 9y ago
I agree that there are many missed and incorrect diagnoses made not least by specialists.
115.
by sungam 9y ago
Of course it is possible to miss the diagnosis. My point was that this is not an obscure disease that a dermatologist would not know about.
116.
by sungam 9y ago
Schnitzler syndrome, whilst rare, is well known to dermatologists and is in the differential diagnosis of chronic urticaria (hives). Not to take away from the resident that made the diagnosis but if the patient had been seen by a dermatolog
117.
by sungam 9y ago
I have shown that in elderly individuals essentially the entire epidermis stem cell compartment, whilst having normal morphology, is occupied by clonally expanded mutant stem cells:- https://www.nature.com/articles/s414
118.
by sungam 9y ago
I think far more likely that the predominant variable is the expansion of mutant clones over time to occupy large fractions of the stem cell reservoir.
119.
by sungam 9y ago
Agree. No doubt immunosenescence contributes to the increased rate of malignancy at older ages but the spectrum of cancers seen in immunosupressed individuals does not that match seen in the elderly.
120.
by sungam 9y ago
How do you account for the observation that incidence of cancer in young, immunosupressed individuals (e.g. solid organ transplant recipients), whilst increased, is no way comparable to that seen in elderly individuals?

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