sooheon

20 ms·

241.
by sooheon 5y ago
The keyboard shortcut to switch to them in ctrl-down (or whatever you have set to "Application windows") and then arrow keys.
242.
by sooheon 5y ago
1. CMD-tab to application with minimized window. 2. Ctrl-down for "Mission Control > Application windows" 3. Down arrow to select minimized 4. Enter This even works when all windows of application are minimized. It's a tra
243.
by sooheon 5y ago
It's just the difference between a depth=2 tree and a flat list. What's better depends on your access patterns, but at least semantically, the tree makes a lot more sense to me.
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by sooheon 5y ago
Humans fear novelty more than actual danger itself. This is also why nuclear consistently fails to gain traction while fossil fuels continue the status quo of killing millions.
245.
by sooheon 5y ago
There exist MR studies on cholesterol levels vs. longevity as well: https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bcp.... These nits really aren't worth picking over when you haven't prese
246.
by sooheon 5y ago
Notably DeepMind had a recent paper on using transformers to predict long range interactions in gene expression: https://www.nature.com/articles/s41592-021-01252-x
247.
by sooheon 5y ago
Yeah good point. The point is not that lower serum cholesterol must be monotonically better down to 0, just that observational studies like this overestimate the the minimum due to confounders like underlying disease.
248.
by sooheon 5y ago
> it doesn't prove that reducing cholesterol by other means wouldn't increase mortality risk. It's possible, for instance, that lower cholesterol does increase mortality, but that statins are offsetting that increase in so
249.
by sooheon 5y ago
I assume we know nothing, but multiple RCTs with tens of thousands of participants in agreement tend to be the strongest forms of evidence we have in clinical matters: https://www.cochranelibrary.com/cdsr/doi/10.10
250.
by sooheon 5y ago
I don't know 100%. I'm not a lipidologist or god. However, logically my post does not entirely rely on knowing the precise in vivo mechanism of statins and their causal health effects. We only need to see that in RCTs, lowered cho
251.
by sooheon 5y ago
There are efforts to study multivariate, nonlinear biomarkers, especially with the advent of deeper molecular profiling (i.e. transcriptome, proteome).
252.
by sooheon 5y ago
You're welcome. Here's to informed health!
253.
by sooheon 5y ago
TLDR: this observational study replicated the known phenomenon that (seemingly paradoxically) low cholesterol is correlated with increased risk of mortality. It's an ongoing debate whether low cholesterol is directly bad for you, or it
254.
by sooheon 5y ago
No, scientists have studied this phenomenon for decades. This is a study specifically interrogating the direction of causality for low cholesterol and mortality: https://www.ahajournals.org/doi/10.1161/01.cir.92.9.
255.
by sooheon 5y ago
> increases mortality Implies a causal relationship. In reality, it's much more likely that causality points the other way, and an underlying disease like cancer is causing low cholesterol: https://www.ahajournals.org&#x2
256.
by sooheon 5y ago
No. Please don't make health decisions off of incorrect inferences from observational studies. https://news.ycombinator.com/item?id=30893041
257.
by sooheon 5y ago
This is not a new finding. It's common enough to have a name: the cholesterol paradox ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374572/ ). Also replicated in a more recent n=100k Denmark study: http
258.
by sooheon 5y ago
Well the optic nerve has a direct route to the brain (where the placebo effect begins)
259.
by sooheon 5y ago
Yeah I was very into personal electric last mile transport for a while, but realized you can't beat the city bike rentals for convenience and 80/20 efficiency. If they're not available I just walk.
260.
by sooheon 5y ago
The downsides of weight, safety, exercise were what got me to back to bikes after 4 years and thousands of km on a OneWheel. I gained ~10% bodyweight while I commuted with the OW and lost it all within a couple months of biking.
261.
by sooheon 5y ago
They are abusing intellectual property monopoly.
262.
by sooheon 5y ago
> is Amazon's shop owned to the exclusion of everyone else? Not the online store. The land taken up by their supply chain, offices, and datacenters is all they are excluding others from using. > Google's search is a utility
263.
by sooheon 5y ago
I'm glad you're interested. > So Apple has organised (against the 2nd law of thermodynamics) a collection of companies that moves chips and aluminum and glass into a box in a store near me. [...] That is a form of development &
264.
by sooheon 5y ago
You'd be interested in Progress and Poverty, a seminal work by late 19th century economist Henry George that tackles these issues of monopoly (of land, ideas, network effects) and their economic consequences. Full text here: https:&#x
265.
by sooheon 5y ago
> Here is the article: https://pubmed.ncbi.nlm.nih.gov/35082139/ It’s important to observe that “omega 3 fatty acid supplementation with or without vitamin D reduced the autoimmune disease rate by 15% (not statistic
266.
by sooheon 5y ago
2000 IU is an almost arbitrary number anyways. The precise input is obviously less important than the resulting serum levels, quantifiable by a simple blood test measuring 25-hydroxy D. A recent meta-analysis of 32 studies ( https:/&#x
267.
by sooheon 5y ago
> Plus intense sunlight carries the risk of cancer. Not the whole truth. Broad spectrum sun exposure is correlated with a decreased risk of death from melanoma. The presence of solar elastosis (basically sun damaged skin) was associate
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by sooheon 5y ago
This very post references a randomized, double blind, placebo controlled trial. It's an intervention over 5+ years that showed 22% reduction in autoimmune disease, not a correlative study.
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by sooheon 5y ago
What is certain about accidents is that they are outside of our control. They are not what anyone would call, of our own free will.
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by sooheon 5y ago
Wow cool. Sounds like semantic satiation.

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