rpkoven

12 ms·

1.
by rpkoven 2y ago
My thought is yes. There has to be neuronal death as the neuron becomes less sensitive to insulin and metabolize glucose.
2.
Muscle-Brain Crosstalk: How Skeletal Muscle Influences Neurocognitive Function(gethealthspan.com)
9 points by rpkoven 2y ago|0 comments
3.
The Role of Inflammation in Exercise-Induced Reduction of Cellular Senescence(gethealthspan.com)
7 points by rpkoven 2y ago|0 comments
4.
by rpkoven 2y ago
The dynamic, wave-like model of aging aligns with the concept of quasi-programmed aging, which suggests that aging is not merely the result of accumulated damage, as proposed by the wear-and-tear model. Instead, aging reflects the unintende
5.
by rpkoven 2y ago
Our genes are programmed for growth, growth gets out of control, leading to our death
6.
by rpkoven 2y ago
What is the cadence of giving blood to offload iron?
7.
by rpkoven 2y ago
So basically I don’t have to exercise anymore?
8.
by rpkoven 2y ago
No pain, no gain. Article makes sense. No hacks.
9.
by rpkoven 2y ago
Interesting that they could quantify the differences in energetic output from a mitochondrial level. I guess it’s time to start running again.
10.
Rapamycin: Could a simple pill add years to your life?(irishexaminer.com)
3 points by rpkoven 2y ago|2 comments
11.
by rpkoven 3y ago
Vigorous exercise enhances the heart's plasticity, which refers to its ability to adapt and remodel itself in response to increased physical demands. This includes increasing the size of the heart chambers, improving the heart muscle&#
12.
by rpkoven 3y ago
In the first four hours following protein ingestion, the study observed a 20% higher rate of muscle protein synthesis in participants who consumed 100 grams of protein compared to those who ingested 25 grams. This difference became even mor
13.
Are the Longevity Benefits of Acarbose Rooted in Its Role on the Gut Microbiota?(gethealthspan.com)
74 points by rpkoven 3y ago|24 comments
14.
by rpkoven 5y ago
APOE4 carriers have impaired free DHA transport into the brain because of APOE4-mediated degradation of the blood brain barrier, but this degradation does not impair how DHA-lysoPC enters the brain
15.
Default Alive – Surviving the Startup Ramp Up(dantawfik.medium.com)
3 points by rpkoven 6y ago|2 comments
16.
by rpkoven 6y ago
I don’t think Tim Ferris’s book was bad. He mainly talked about automations, but a lot of the tech bro take on it is cringe.
17.
by rpkoven 6y ago
Do you think his podcast is interesting though?
18.
by rpkoven 6y ago
I don’t think it’s unethical
19.
by rpkoven 6y ago
I think you are right. It’s how people ran with the book that is a little cringe
20.
The alternative to the four-hour workweek mindset(techcrunch.com)
3 points by rpkoven 6y ago|1 comments
21.
The Rock Taking on Trump's Leadership and Praising Black Lives Matter(youtube.com)
3 points by rpkoven 6y ago|1 comments
22.
Craftsmanship-Rethinking the 4 Hour Work(dantawfik.com)
5 points by rpkoven 6y ago|1 comments
23.
I Have a Reason to Live(stitcher.com)
3 points by rpkoven 6y ago|1 comments
24.
The Craftsmen–The Alternative to the 4 Hour Mindset(medium.com)
9 points by rpkoven 7y ago|0 comments
25.
For Founders: The Feature Death Trap(medium.com)
7 points by rpkoven 7y ago|0 comments
26.
by rpkoven 7y ago
I think being in the Stanford engineering ecosystem has been a positive funnel into starting a tech company. Whereas in NYC it’s more likely you’d get recruited by a finance company.
27.
For Founders: The Tunnel Vision Trap(dantawfik.com)
5 points by rpkoven 7y ago|0 comments
28.
Craftsmanship – The Alternative to the Four Hour Work Week Mindset (2018)(dantawfik.com)
143 points by rpkoven 7y ago|43 comments
29.
by rpkoven 7y ago
I’ve heard of the benefits of mdma therapy
30.
by rpkoven 7y ago
We developed new features thinking each feature would cause the inflection point we were looking for. ‘Ticketing will be a game changer,’ or ‘this new mobile app will allow us to sell at a higher price point.’ Each time we barely pushed the

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