rotexo

15 ms·

121.
by rotexo 6y ago
Exactly. I just bought a Switch Lite and I'm playing Breath of the Wild for the first time. It has been 15+ years since I played a Zelda game seriously (last one I played was Wind Waker), and I am just blown away. I'm lucky to be
122.
by rotexo 6y ago
Can you offer a source on the claim that an mRNA vaccine would permanently alter your genome? I have a PhD in microbiology, and I would be VERY surprised if an mRNA vaccine did that.
123.
by rotexo 6y ago
SARS-CoV-2 genome size is ~30 kb [1], influenza A genome size is ~14 kb [2]. A protein encoded in the SARS-CoV-2 genome is predicted to have exonuclease proofreading activity, which would result in a lower mutation rate [3]. [1] https:&#x2
124.
by rotexo 6y ago
It is difficult to see what your actual criticism is here. Do you object to the tone that people take when criticizing anti-vaccine arguments? Or do you object to the faith that people have in the overall utility of biomedicine? I agree tha
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by rotexo 6y ago
Isn’t that B in the grandparent?
126.
by rotexo 7y ago
they cover this in the FAQs, which are worth reading. They indicate that, if distancing measures are maintained, the first wave will be done by early June. They explicitly say that a second wave is likely unless extra measures, like contact
127.
by rotexo 7y ago
Note the caveat: ‘ The projections assume the continuation of strong social distancing measures and other protective measures.’
128.
Model of COVID19 outbreak hospital resource use in US(covid19.healthdata.org)
12 points by rotexo 7y ago|1 comments
129.
by rotexo 7y ago
It seems to me the author would only be satisfied with retrospective population serology tests (which determine if individuals in the population have ever been infected with SARS-CoV-2), as opposed to RT-PCR, which gives you a single time p
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by rotexo 7y ago
Many thanks to everyone for their thoughts. It will take me some time to digest it all.
131.
by rotexo 7y ago
I am facing a similar issue with my aging parents. They are both 70+. They both get respiratory issues every year. My Mom in particular is convinced she is healthy and doesn't need to worry about it. I understand why she is resistant t
132.
by rotexo 7y ago
At the top of the article: “ Note: The study at the centre of this article on the transmission of the coronavirus was retracted on Tuesday by the journal Practical Preventive Medicine without giving a reason. The South China Morning Post h
133.
by rotexo 7y ago
There are emerging CRISPR-based diagnostic tools, but they are still very experimental and novel. I wouldn’t be surprised if a rollout took almost as long as a vaccine. https://mammoth.bio/2020/02/15/white-pap
134.
by rotexo 7y ago
Yeah I was thinking transport over ethernet would be cool
135.
by rotexo 7y ago
I've been fantasizing a little about a new modular format, or at least a new category of synth controllers, taking advantage of the higher resolution of MIDI 2.0 for some modulation signals. I could be wrong, but I thought MIDI 2.0 was
136.
by rotexo 7y ago
We already have RT-PCR assays for COVID-19, which is pretty affordable in terms of reagents (whether that translates to affordability overall is a different story). There are supposed to be six labs in the US performing screening for COVID-
137.
by rotexo 7y ago
I am curious if we will see rapid deployment of one of the rapid point-of-care CRISPR-based detection systems (like https://mammoth.bio/wp-content/uploads/2020/02/A-protocol-fo... ) Probably unlikely, giv
138.
by rotexo 7y ago
I am curious about how exactly you go from observing biological complexity to doubting the biomedical community's confidence in vaccination as a safe and effective means of combating infectious diseases.
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by rotexo 7y ago
male painted bunting, in east texas!
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by rotexo 7y ago
Whole genomes bring their own complications. You will have tons of variants of unknown significance in each patient. Then you would want functional data to see if there is an impact on transcription/translation of the protein, and the
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by rotexo 7y ago
Worth noting that the sequencing for this analysis was performed from 2012-2016. 4 years is a long time in the NGS world, and it is highly likely there have been chemistry improvements since then. Though it wouldn’t surprise me if inconsist
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by rotexo 7y ago
In the East San Francisco bay area, I have observed that the crows behave in an incredibly habitual fashion. Every evening, huge crowds of them gather near Lake Merritt in Oakland. I see them streaming over my apartment in Berkeley a little
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by rotexo 7y ago
An alternative viewpoint: music is anything presented. See John cage’s 4’33”. No sounds or patterns to be found.
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by rotexo 7y ago
My understanding was that the parent's parent was saying that the expectation of returns in a mutual fund is predicated on continued economic growth, predicated on there being more people in the future to enact all that growth. Society
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by rotexo 7y ago
Ooh, corpus based concatenative synthesis! I look forward to reading through these links. The only features that I have had luck with are spectral centroid (for ‘brightness’) and some measure of loudness, but I have always wanted more. Than
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by rotexo 7y ago
right, but that's for sequestering the carbon, not turning it into a valuable product like a fuel, unless I'm mistaken
147.
by rotexo 7y ago
You might be interested in the hide-and-seek variant Sardines. One person hides, with a group of seekers. Seekers that find the one who hides have to hide with them, until one seeker is left. There is nothing like the feeling of looking aro
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by rotexo 7y ago
It is probably the result of some kind of cognitive bias, having heard similar things for a long time, but I have been captivated by crows ever since I moved to the bay from Austin. In Austin, the resident blackbirds (grackles) just seem li
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by rotexo 7y ago
Is it possible that you are conflating ‘function’ with ‘reason?’ As a biologist, my perspective is that thinking in terms of functions (ie, the G6PD enzyme functions to produce NADPH and substrate for pentose phosphate using glucose-6-phosp
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by rotexo 7y ago
Elsewhere in the comments they say that their consortium includes a yeast isolate. Yeast are fungi.

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