robbiep

49 ms·

571.
by robbiep 5y ago
It might be downvotes because the op didn’t read the article, which isn’t about a vaccine (the article says there was one but it was discontinued) but about the Lyme equivalent of PREP
572.
by robbiep 5y ago
Your language suggests that you’ve already decided how you would like to believe, and your rebuttal to the OP fails to move past the first couple paragraphs of the guardian article or appreciate the other sources that are linked in the arti
573.
by robbiep 5y ago
There are also what I think are reasonable models for providing people with ownership of an app but also being able to charge upgrade fees (for example, TablePlus, Dash, Sublime etc)
574.
by robbiep 5y ago
That’s reasonable logic but for me with a company subscription and previously having been an individual purchaser with my backup in iCloud rather than on 1 pass servers, it doesn’t really tilt the balance - I also hate electron with a passi
575.
by robbiep 5y ago
I didn’t know this is a thing… I’ll have to look into it - thanks
576.
by robbiep 5y ago
Is your argument that everyone has the same capability?
577.
by robbiep 5y ago
It’s post covid, and it’s ostensibly to ensure that they don’t just want to come back again soon which will cause more upset with the government because they will ‘take’ away incoming seats from stranded Australians (currently around 30,000
578.
by robbiep 5y ago
you can usually get one read out of it through incognito/private
579.
by robbiep 5y ago
I don't know or haven't seen any evidence that polymerase mutations are responsible for the increased R0 of Delta, although it's certainly possible. What we do know is that the Spike protein is essential for COVID cellular bi
580.
by robbiep 5y ago
I don’t know if you can make that bet - evolution of the virus needs to conserve the current mode of cellular entry and attachment and fitness of spike appears to be the main driver at present - and then spike mutation has driven drift from
581.
by robbiep 5y ago
The Tokyo medals are around 500g each, so while those are nice estimates for the minimum dimensions, if the Tokyo golds were of the same weight and heft they have been made (and also 100% base metal) then you’d be looking at around $15m USD
582.
by robbiep 5y ago
As of Wednesday you don’t need a gp consult prior to AZ. Also, should be pointed out that it is not thrombophilias in general but immune thrombophilias that are of concern for AZ (ie factor V lieden and others are fine per ATAGI advice whic
583.
by robbiep 5y ago
Everyone I know in sydney is quite frustrated but also fairly compliant, it’s a reasonably relaxed lockdown compared to others or Melbourne’s (unless you’re in one of the 8 local government areas at the epicentre). Personally, and as a doct
584.
by robbiep 5y ago
I think that what you replied to is the comment ’ am always fascinated when I hear other nerds describe the process of learning Western history as "begin with the Greeks.’ When I think everyone who is also commenting here recognises
585.
by robbiep 5y ago
I don’t think we’re disagreeing, it’s just at what point do you try to pick up the threads of history to try to begin to understand things? One of the most fascinating things I find of our history is Linear A & B and Minoan civilisation
586.
by robbiep 5y ago
Regarding your fascination about western history ‘beginning with the Greeks’ I would say the reason why is fairly obvious if you follow the history. Despite the locus of civilisation being in Mesopotamia and Egypt from 5-6000BCE to 500BCE b
587.
by robbiep 5y ago
You phrased COVAX as though it was a vaccine in itself, rather than a program, and it is not at all clear that was your intention
588.
by robbiep 5y ago
As I understand it, COVAX is the WHO program name for distribution of vaccines to developing countries, and will potentially include all vaccines, unless you have other information?
589.
by robbiep 5y ago
In fact, alcohol can extend life in low doses. There’s a chart we were shown in Med school with DALYs of different drugs and while alcohol had a big negative side it also had a positive side which was the only one
590.
by robbiep 5y ago
They last 10 years ‘or so…’ some up to 17-20, so there’s a variability there, but they fail gracefully so you can monitor which is nice (as another commenter pointed out). Tou can replace with transcutaneous valve replacement (like a stent,
591.
by robbiep 5y ago
I may be speaking from 7-8 years ago when we were still in the dawn of TAVIs but the cardiothoracic surgeons I worked with generally put tissue valves in <50, as TAVIs last less. So tou could do tissue valve, plan for a TAVI later, then
592.
by robbiep 5y ago
We’re talking about a situation where big investments in lithium batteries have lead to a possible massive increase in the cost of lithium production, and you’re assuming we wouldn’t see similar enhancements in hydrogen production - electro
593.
by robbiep 5y ago
Just because hydrogen is mostly produced from carbon sources right now doesn’t mean it would be with significant scaling of hydrogen as a fuel source, it could be easily produced from electrolysis of water from renewable sources if the inve
594.
by robbiep 5y ago
That’s not really true around selection of valve, it’s all about fitness. A lot of younger people will have tissue valves, because they can have another one after (probably, if they don’t have too many Comorbidities) and it’s a better trade
595.
by robbiep 5y ago
Pulsating vessels are really important. There’s a bunch of evidence of the physiological benefits to having a pulse. Doesn’t mean you can’t, but it’s good for you, you evolved to have it. You can convince stem cells to differentiate into ar
596.
by robbiep 5y ago
You use bovine or porcine generally. They last about 10 years. Metal valves last 30 years but require anti coagulation. Since porcine and bovine valves are zero from à immunogenicity standpoint, they’re ideal unless we could get human ones
597.
by robbiep 5y ago
Yes sorry I should have specified, PD-1s. Was 4am in australia on mobile and wasn’t in the mood to reference. Sorry
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by robbiep 5y ago
The cancers that are treated successfully in children are the blood borne ones (mostly leukemias) and generally because they’re easier to wipe out and replace the marrow with. Some Childhood brain tumours are also very successfully treated,
599.
by robbiep 5y ago
Often (as in this instance) big breakthroughs are multiples steps downstream from the initial grants or come from a collection of research. There’s a reason for the saying ‘standing on the shoulders of giants’
600.
by robbiep 5y ago
Where did you live previously? Australia has one of the highest rates of asthma in the world, with higher rates in rural and regional areas than the cities. Sydney also has a high rate of moulds which can be triggers due to its often humid

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