3 ms·
The cancers that are treated successfully in children are the blood borne ones (mostly leukemias) and generally because they’re easier to wipe out and replace t
by robbiep 5y ago
The cancers that are treated successfully in children are the blood borne ones (mostly leukemias) and generally because they’re easier to wipe out and replace the marrow with. Some Childhood brain tumours are also very successfully treated, and most other adult cancers children don’t get. Sarcomas still kill people left right and centre though.
The truth is that we’re already peeking out of the dark ages of chemotherapy. Immunothérapies have revolutionised the field and new stuff coming online is incredible. When I started medical school 11 years ago the 5 year survival of metastatic melanoma was close to 0%. It’s now close to the population average (well, not really, but it’s greater than 50%). Records are being smashed
- et2o 5y agoMetastatic melanoma? I haven’t seen any data showing close to 50% survival rate, where are you looking? Just managed a young patient with metastatic melanoma and very poor prognosis.
- Herodotus38 5y agoI think they were referring to pd-1 inhibitors. I’m not an oncologist but that generally fits with what I’ve seen as a hospitalist. FWIW I personally know someone who has survived > 5 years who received it right when it cane out. Here’s a paper supporting: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019511/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019511/
- jcims 5y agoPD-1 inhibitors seem like magic when they work. Unfortunately they don’t work in every case, but it’s abundantly clear when they do that the immune system is good at killing unwanted cells roaming around the body. *smacks forehead*
- robbiep 5y agoYes sorry I should have specified, PD-1s. Was 4am in australia on mobile and wasn’t in the mood to reference. Sorry