ralusek

20 ms·

241.
by ralusek 3y ago
Yes, the delivery system definitely has that drawback. However, the lipid nanoparticles as a delivery system have problems of their own, which I laid out in a sibling comment to your own. But my question is more related to the pop-science p
242.
by ralusek 3y ago
As another note, the mRNA platform has a few concerns that the viral vector vaccines do not. In particular, the delivery of the mRNA payload is done via lipid nanoparticles that are not in any way targeted to a specific cell type. The Europ
243.
by ralusek 3y ago
The viral vector vaccines are a very similar development as the mRNA vaccines, and I'm curious as to why they've received less attention as a technological wonder. Brief summary: Goal of vaccine is to get antigens in body in order
244.
by ralusek 3y ago
Here's to another year of the word Göbeklitepe playing on repeat in my head.
245.
by ralusek 3y ago
Yes, it's incredibly odd. Most US large ETFs and crypto have basically been in lockstep for much of the last few years. Same with housing, delayed a bit. It seems to indicate that that we're seeing when we look at the price of the
246.
by ralusek 3y ago
I love my Galaxy phones. I draw with the stylus constantly. I think they have better cameras. I love the Android back button. After almost 15 years of Android, I'm buying an iPhone specifically for iMessage. I had a daughter, and I&#
247.
by ralusek 3y ago
I get anxiety about humanity forgetting how to build foundational tools. I feel better when the occasional weirdo dips down into the weeds to try things from scratch. They're often writing blogs and sharing their knowledge, which is ni
248.
by ralusek 3y ago
Postgres json/jsonb
249.
by ralusek 3y ago
Stephen King on cocaine in the 80s was very real.
250.
by ralusek 3y ago
Tangentially related: what is the benefit of Deno KV over something like S3? I see option for atomic transaction, which is nice, but otherwise fewer features for far higher cost. Is it mostly speed?
251.
by ralusek 3y ago
Got it. That makes much more sense.
252.
by ralusek 3y ago
That seems incredibly unreliable. Justin Bieber videos can have ratings in the dirt and billions of views. I can imagine that the are plenty of esoteric items on gumroad which solve something super specific really well for a small audience,
253.
by ralusek 3y ago
US spies on itself and everyone else.
254.
by ralusek 3y ago
Meanwhile quadruple glazed window enjoyers have their laugh at your expense.
255.
by ralusek 3y ago
Their search isn't bad imo. I actually use it pretty frequently for things I barely remember, and it's pretty solid.
256.
by ralusek 3y ago
Nobody can be trusted with the future of AI, but neither can anybody stop the future. The only restraint against AI will be AI, not regulations, but I'm worried that any equilibrium that's reached will be happening at a scale with
257.
by ralusek 3y ago
> The goal was that a human could be dropped in the space from anywhere in the world and navigate their surroundings. I see it as a worthy goal. It's funny, because I've often used an expression that's almost a perfect inv
258.
by ralusek 3y ago
Limit the conversation to atmospheric carbon dioxide. https://www.climate.gov/news-features/understanding-climate/... The carbon dioxide in the atmosphere has almost doubled since the industrial revolution. Since
259.
by ralusek 3y ago
Nvidia is interesting on multiple fronts. For one, GPUs aren't just useful for ML. Secondly, ML isn't just LLMs. I also find their bet on USD to have been vindicated by other industry players, and their Omniverse/digital twin
260.
by ralusek 3y ago
What's interesting is that neither of those drive inflation. Inflation is the expansion of the money supply, and there is a sudden attempt to redefine it as increased costs of goods and services. Money supply goes up, costs of assets f
261.
by ralusek 3y ago
What about debt to wages?
262.
by ralusek 3y ago
It is explicitly known the the training data cutoff for GPT4 is September 2021. While we can assume that feedback is taken into consideration for future training of new models, the training data used to train all current models is a specifi
263.
by ralusek 3y ago
I get very bad headaches from eating seaweed snacks. I absolutely love them, mind you, but it's like clockwork. I've had this postulated to be as the result of MSG, but that doesn't track with me. There's MSG in all sort
264.
by ralusek 3y ago
It seems as though we currently have the technology to make a major dent in the release of carbon into the atmosphere. Due to the negative third party externality of something affecting the entire planet, this is a rare case where there sho
265.
by ralusek 3y ago
People are just now fed up with those things, at their lowest point in history?
266.
by ralusek 3y ago
So far the person making the largest push to Mars also owns the largest electric car company, a solar power company, makes battery packs for storing the power from unpredictable renewable energy sources, advocates for nuclear, and set up a
267.
by ralusek 3y ago
iPhones have LIDAR, so you could already make that case. I doubt that all LIDAR is the same, though, and there are more expensive solutions for increased range and speed, reliability, durability. Tesla's was more likely motivated by su
268.
by ralusek 3y ago
Being a police officer is a privilege. The population grants you the authority to detain us, accuse us, and even kill us. Few professions should be subject to higher scrutiny.
269.
by ralusek 3y ago
They aren't legislating from the bench. Legislating from the bench is the opposite of what is being done here. The role of the judicial is to look at laws and actions and determine if they're legal within the meta framework. That
270.
by ralusek 3y ago
It seems as though national debt has transitioned from something that ever needs to be paid off to instead just being a graph of inflation. The Fed holds the majority of the US Debt, and that will likely increasingly be the case. Government

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