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podgaj
searching PlanetScale…
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38 ms
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331.
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by
podgaj
6y ago
That is what I tell everyone struggling with unknown health issues: There are no diseases, only symptoms.
332.
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podgaj
6y ago
Legally, no. Functionally, yes. Even though they no longer mail checks you need a bank account as well. And then the issue with getting in contact with you. There is only wealth in this country because we treat the most vulnerable like garb
333.
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podgaj
6y ago
If there is any test you should get is is a serum amino acid test. I have done much of the foot work on ME/CFS. Start looking into aldehydes (malondialdehyde specifically) and the role they play. Also, if you can get your genetics from
334.
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podgaj
6y ago
This is true, but smart doctors know how to work the system. But I am on medicare so it might be easier for my doctor.
335.
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podgaj
6y ago
I am in the U.S. and I am lucky because I am white and my OCD kept me from using any drugs to cope. But I was hospitalized several times and had a few suicide attempts, plus my family history. Those are all big factors in getting disability
336.
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podgaj
6y ago
Both myself and my mother were diagnosed with ME at one point. And I agree, even when my tests came back weird my primary care doctor would say, "What do you want to do now?" Argh
337.
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podgaj
6y ago
Since we do not make enough BH4 (tetrahydrobiopterin) with this enzyme deficiency we cannot metabolize the amino acids needed to make serotonin, dopamine, and Nirtic Oxide. And then some of these amino acids turn into trace amines that act
338.
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by
podgaj
6y ago
I do not know how many people here have "Depression, Anxiety, Panic Disorders" but I am on disability for all three and it runs in my family on my mother's side. So what is this article saying? Me and my family just do not ha
339.
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podgaj
6y ago
I did not mean to imply you were in the cult of Elon. As a teacher of American History I have read countless diaries of these kids, they were brainwashed while they were in the scouts. I do not blame them either. >Those are his companies
340.
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podgaj
6y ago
>some people are 'all in' about the cause and are putting their Lives at risk Jesus, the frickin Nazi Youth did the same thing! Why don't people ever see the leader worship and authoritarianism (fascism) in corporations?
341.
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podgaj
7y ago
Wow, Stephen Wolfram has just rediscovers Daoism...
342.
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podgaj
7y ago
I have looked into altitude and NOS activity a lot because of the issues I have at altitude as well. This is largely controlled by the genetics of NOS2. https://www.sciencedirect.com/science/article/pii/S00029
343.
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podgaj
7y ago
You think I shifted, but I did not. If you would have given me an opportunity I would have explained.
344.
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podgaj
7y ago
I know a tin of oysters has over 250mg of zinc so there is that. But yes, more zinc in meat for sure, and phytic acid will play a role reducing absorption, but deficiency could depend on genetics a lot as well.
345.
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podgaj
7y ago
An ACE inhibitor means that you would have less ANGII which looks like it would be of benefit is what they are finding is true. https://www.medrxiv.org/content/10.1101/2020.04.07.20056788v... ACE inhibitors lower
346.
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podgaj
7y ago
I think it may matter more if you are zinc deficient when you are infected. But Zinc does not need to be in the cell to help. It will also increase ACE2 activity, which is more important they are finding. When the ACE2 is destroyed, there i
347.
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podgaj
7y ago
I do not think I will be here long. It is even worse than it has been in academia. I will share this with you, I do not think hydroxychloroquine is needed, only high dose zinc. It is looking more like lower ACE2 activity is causing the majo
348.
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podgaj
7y ago
I agree with you. I am wondering about how NOS enzymes (like NOS2) might play a role since they are expressed at high altitudes and COVID is looking a lot like high altitude sickness by one doctor in NYC. https://www.ncbi.nlm.nih
349.
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podgaj
7y ago
I lave Lupus which is what led me to research since my mother had it as well I saw it as genetic, and it is for us. There of many people with common disease living on on the nature----nurture spectrum. But the nurture part is largely overlo
350.
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podgaj
7y ago
Yes, speculation is the fertilizer of hypothesis. All anyone has at this point with COVID is speculation. How can you say vasodialtion is not a vector in COVID19 outcomes? It is vasodialtion that increases capillary permeability leading to
351.
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podgaj
7y ago
Apparently this is not presenting in the lungs as either ARDS or pnemonia which has been the problem. There is a doctor in this thread who was saying vents were making O2 levels drop so they just provided low pressure oxygen. My focus more
352.
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podgaj
7y ago
I was just using the PAH as an example, but the issue in the lungs results from vasodilation (please correct me anyone if I am wrong). So vasocontriction might slow the leaking of fluid into the intercistal space. Regarding the zinc deficie
353.
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podgaj
7y ago
I was not giving advice. You are taking it as advice. That is stupid. Talking is by no means useless, what an odd thing to say!
354.
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podgaj
7y ago
The hypoxia issue is more of a physical problem caused by inflammation. Think about trying to push a marble through plastic, that is what the vents are trying to do with the oxygen that is trying to get from the aveoli to the capillary. Ven
355.
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podgaj
7y ago
I was speaking about your inquiry into the damage to the heart and I felt that oxidative stress could better explain that damage. Zinc replacing the iron in heme might help in the lungs. Both aspects would involve a zinc deficiency.
356.
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by
podgaj
7y ago
I would suggest that any down or up votes must be accompanied with a reason and reply then, yes? Or maybe just get rid of the voting and let the comments speak for themselves.
357.
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by
podgaj
7y ago
Thanks!
358.
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podgaj
7y ago
Where the bleep did I say that? It might be BAD if they are on a vent to increase NO. I am talking about before or at the beginning of infection so they never have to get on a vent.
359.
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podgaj
7y ago
>So my general impression is that red blood cells are failing to get adequate oxygen There does not seem to be evidence of this. The trouble breathing and O2 exchange is happening because the aveoli are collapsing in bad cases. This occu
360.
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podgaj
7y ago
Actually it could be bad. I AM JUST TALKING. It could be that increasing NOS at the wrong time might make it harder to get oxygen. It might be beneficial at the begining of the infection but bad if you already have pulmonary vasodilation. T
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