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pcrh
searching PlanetScale…
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45 ms
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661.
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pcrh
9y ago
In the UK at least, independent research at pharmaceutical companies or Contract Research Organizations typically costs 1.5- to 2-fold what it costs at a University. Mostly because they pay higher wages than PhD students get, but also becau
662.
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pcrh
9y ago
But you can have capitalism without free trade, or even many rights at all. Liberal freedoms and rights tend to favor capitalism as an economic system, but not the other way around.
663.
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pcrh
9y ago
It isn't capitalism that prevents abuse of power by the wealthy. It's liberal democracy, and human rights enshrined in laws that are enforced.
664.
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pcrh
9y ago
It isn't clear to me where you're getting these numbers from... where do you find 35 WT and 35 mutant? Could you point me to the data for WT vs mutant embryos in this experiment? Edit: in case you're referring to the table yo
665.
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pcrh
9y ago
My point is that there's no obvious harm implicit in denying people an inheritance. They did nothing to earn it. There's no inherent right to be bequeathed wealth; that this is evident is that it is nigh on impossible to sue one&#
666.
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pcrh
9y ago
The evidence is that allowing large inheritances is harmful to society at large. It allows for an accumulation of economic influence within too few hands, and the creation of an entrenched elite. The "Founding Fathers" of the US w
667.
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pcrh
9y ago
I've now scanned the original article. As I understand, they injected ova with the CRISPR/CAS9 plasmids and then fertilized them with mutant sperm. The goal was to see if they could achieve CRISPR-mediated repair of the mutant all
668.
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pcrh
9y ago
You're correct in that it's foolish to institute an uncollectable tax, but I don't think inheritance tax necessarily falls into that category any more than, say, capital gains taxes.
669.
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pcrh
9y ago
I haven't read the original study... However, I suspect that selective lethality of targeted cells would not account for this outcome. The process involves a single cell at the outset.
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pcrh
9y ago
Tax avoidance is a perennial problem, to be sure. There's always an "arms race" between the taxers and the avoiders, but that isn't a reason not to have taxes in the first place.
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pcrh
9y ago
I suspect a lot of it has been invested in overseas locations, including manufacturing operations globally. It may be that the money did indeed "trickle down", but not into the US.
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pcrh
9y ago
Inheritance tax was the original solution to this. Someone could be as rich as Croesus during their lifetime, but on their death returned the money from whence it came. Their offspring could benefit from a generous endowment of a proportion
673.
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pcrh
9y ago
Before the strike they had no certainty about the third year, though, did they?
674.
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pcrh
9y ago
I'm amused at the sick child story. At first reading what came to my mind was how the chickens might for a brief time see a red barrow with food as their whole world.
675.
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pcrh
9y ago
The term "significant" is itself part of the problem. In statistics it is often used to describe an arbitrary threshold where a difference between datasets is assumed to be real. In common parlance this term implies "importan
676.
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pcrh
9y ago
>young, energetic, and highly intelligent & analytic That isn't what works in politics... What works in politics is knowing which levers to pull, and having the money or influence (in the right paces) to do pull them.
677.
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pcrh
9y ago
>A myth of capitalism is that the donkey can reach the carrot hanging from the stick if they work harder That's the myth of the "American Dream", not Capitalism per se. Capitalism is more simple, if you have capital, you h
678.
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pcrh
9y ago
The comment on visas potentially refers to the fact that one of the criteria for certain visa categories is that one be distinguished in one's field. Serving as a reviewer demonstrates that one has acted as a judge of one's peers,
679.
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pcrh
9y ago
In the same vein, one of my favorite etymologies is the origin of the word "pedant": "derived from Greek παιδαγωγός, paidagōgós, παιδ- "child" + ἀγειν "to lead", which originally referred to a slave who es
680.
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pcrh
9y ago
Research articles are dense and full of jargon because that is the most efficient way to communicate with their intended audience, which is other researchers. Making a standard research article readable to the lay audience, even if it is al
681.
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pcrh
9y ago
I wonder how many of those would survive multiple hypothesis testing. That is, there are bound to be a number of phonetically similar words that happen to have similar meanings in two different languages. They may not however have common hi
682.
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pcrh
9y ago
The Public Library of Science is an exclusively online series of journals in biology and medicine. They have a fairly nice layout and design. Perhaps aerospace has something to learn? https://www.plos.org/publications
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pcrh
9y ago
The same phenomenon exists in the UK. That is, an apparent disconnect between wages, GDP growth and employment, resulting in lower productivity metrics for the economy as a whole.
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pcrh
9y ago
Out of interest, what exactly do you like about it? It seems similar to several of the more prominent medical or bioscience journals that I frequently read.
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pcrh
9y ago
Indeed, that doesn't seem to be a very plausible contribution to the success of the Mittelstand. In the US, inheritances large enough to capitalize a mid-sized company are usually protected from inheritance taxes through a number of &q
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pcrh
9y ago
That problem exists for almost all innovative work. Generally, a paradigm becomes accepted when the predictions that follow from it are found to hold true. For people to make the effort to test such predictions requires (from a human standp
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pcrh
9y ago
In the long run that is correct. However, in decision making, when work is "cutting edge" the opinions of experts/"key opinion leaders" weighs more heavily, or equal to, data. For example, it is now >50 years sin
688.
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pcrh
9y ago
A similar conundrum exists in UK universities. It was decided that all university lecturers (professors in US parlance) should have a teaching qualification regardless of experience in actual teaching. The solution was to create a series of
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pcrh
9y ago
Heads of state often don't "own" their property the same way a private individual does in that they cannot liquidate their holdings. The Queen of England, for example, can't simply sell Windsor castle. The "personal
690.
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pcrh
10y ago
From Very Hungry Caterpillars.
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