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pcrh
searching PlanetScale…
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35 ms
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481.
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by
pcrh
4y ago
It's quite difficult for researchers to gain access to human brains, needless to say, so the number of studies attempting to find specific oligomeric species in human brain are limited. However (and without attempting an exhaustive sea
482.
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pcrh
4y ago
Scientists are often very circumspect in how they phrase things, but this particular phrasing in the main article is notable: >“This is not a real scientific problem, but it is most unfortunate for general science credibility,” Selkoe wr
483.
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pcrh
4y ago
Not really. There is plenty of criticism of the amyloid hypothesis within the field, and even specifically of the oligomer variant thereof that Schrag focused on. You can even read that criticism in the link I provided. Schrag's inve
484.
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pcrh
4y ago
Unfortunately, it seems that in this case it is the author of the article published by Science (Schrag) who is remiss and has written a poorly-researched article. See the link I provided elsewhere in this thread.
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pcrh
4y ago
Here is a lengthy response from more than 20 researchers in the field [0]. In brief, the claims made in the article above are exaggerated. As someone who works in the field, and who is skeptical of the amyloid hypothesis, I agree. [0] http
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pcrh
4y ago
Income from government-owned assets, borrowing money, and printing money are the principal other sources of government spending. For Romania you can also add disbursements from the EU.
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pcrh
4y ago
Well, there isn't a strict correlation between the taxes people pay and state spending. Typically, taxes cover about 70-80% of state spending.
488.
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pcrh
4y ago
Not less sex per se, but avoiding sexual practices that increased the risk of infection were supported.
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pcrh
4y ago
"Sexual distancing", condom usage, etc, was very well supported by the gay community during the 1980's outbreak of HIV.
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pcrh
4y ago
I believe part of the motivation for this €9 ticket is to reduce demand for Russian-sourced petrol/gas used by private vehicles.
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pcrh
4y ago
Indeed. The whole profession of psychiatry suffers from poor application of scientific research, to the extent that the National Institute of Mental Health once banned reference to the Diagnostic and Statistical Manual of Mental Disorders (
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Aerospace charts a future without jet fuel
(bbc.co.uk)
1 points
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pcrh
4y ago
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1 comments
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pcrh
4y ago
That's interesting. You can see a difference between N and S hemispheres on the same longitude, e.g. North East USA vs Peru and Japan vs East Australia.
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pcrh
4y ago
It would be interesting to compare the number of pubs with the total number of establishments that cater to eating and drinking, e.g. including cafes, restaurants, night clubs, etc.
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pcrh
4y ago
Interesting! In De Filippo et al., they mention that Bacteroidetes sp are absent in urban Europeans, but present in rural Africans; in the OP they mention a similar sounding Bacteroides being present in chimps but not in humans. Is there an
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pcrh
4y ago
I lived nearby for a few years many years ago. While I appreciate the sentiments you express, I can say that the site was all but abandoned for many many years. For a while it seemed likely that the iconic towers would be demolished, as the
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pcrh
4y ago
I think it would be more accurate to state that interactions between APP and presenilin are very likely causative in late onset AD. Currently the known consequence of that interaction is production of Abeta, ergo the amyloid hypothesis. H
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pcrh
4y ago
Curious that you refer to the "space age" in the past tense. Though it might be because the enthusiasm for humans traveling between planets and stars has been somewhat tempered since the 1960's-1980's.
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pcrh
4y ago
The politically powerful and privileged can be quite diverse in their political views.
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pcrh
4y ago
Bio-calorimetry can be used to detect interactions between biological molecules, such as between proteins, drugs binding to proteins, etc, A quick search lead me to this conference, where you can see a wider range of uses of calorimetry in
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Nanokelvin-resolution thermometry at room temperature
(nature.com)
54 points
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pcrh
4y ago
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15 comments
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pcrh
4y ago
That overstates the benefit somewhat. Housing benefit is capped at the lowest third of local market rates, and further capped at £20,000/yr. So a single person reliant on benefits will at best be able to live in shared accommodation. L
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pcrh
4y ago
That's a bit of a rant, but for two of the points you make: 1) you own the house you live in, someone on benefits does not; 2) for the point "I have the benefit of getting literally no help", this is literally incorrect, your
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pcrh
4y ago
Similarly, global warming may become irreversible and runaway. The article suggests the arrival of "some economically advantageous process may be invented that produces disastrous negative global externalities that are hard to regulate
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pcrh
4y ago
And a naked man as well!
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pcrh
4y ago
Well... I remember in 1996 when first working on the US west coast at a research institute that the prof. would have his admin assistant print-out emails; he would hand-write responses that the admin assistant would type into the computer :
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pcrh
4y ago
"Parmesan" means "from Parma", the suffix -esan also occurs in words like courtesan, or partisan.
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pcrh
4y ago
Boris, is that you? Get to work!
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pcrh
4y ago
>If every working American contributed $8,000 in taxes we would have the same revenue You're not arguing for lower taxes; you're arguing for higher taxes on the poorest.
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pcrh
4y ago
The early Ripsaw really does look like the first WWI tanks... https://en.wikipedia.org/wiki/File:Flickr_-_The_U.S._Army_-_...
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