paulrhjtimmers

4 ms·

1. 1.▲
   by paulrhjtimmers 6y ago

   This is the correct answer.
2. 2.▲
   by paulrhjtimmers 6y ago

   Generally better, but the answer is a little more nuanced. We had access to data describing how DNA influences iron levels, and how DNA influences years of healthy life. This showed that the same DNA variations that change your levels of ir
3. 3.▲
   by paulrhjtimmers 6y ago

   If this were an observational study, I'd completely agree. In that case, it could be that people who eat better diets and do exercise happen to have lower iron levels, but it is the diet and exercise that makes them live longer, not th
4. 4.▲
   by paulrhjtimmers 6y ago

   Great and important question! All data we used was corrected for sex. In other words, we knew the effect of DNA on iron levels, and the effect of DNA on lifespan/healthspan, regardless of the person's sex.
5. 5.▲
   by paulrhjtimmers 6y ago

   Great comment! For the iron - ageing link, we used two pieces of data: the effect of DNA on blood iron levels, and the effect of DNA on how long and healthy you live. We found the mutation that causes hereditary haemochromatosis had a large
6. 6.▲
   by paulrhjtimmers 6y ago

   Hi there, I'm one of the study authors. Iron plays many roles and is needed for your body to function correctly, but we found people who had higher blood iron levels because of their genes were getting diseases earlier in life and had