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patrec
searching PlanetScale…
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75 ms
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721.
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by
patrec
7y ago
False dichotomy. No one should be using shitty byte code interpreters like (c)python for real production work. Or at least stop whining about global warming. The real alternative is AOT. Also in many cases having it's much better to tr
722.
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patrec
7y ago
Two points: 1. People don't just start to magically teleport around if you restrict their travel. I know that defies common wisdom, which is presumably why the UK and others kept (keep?) importing people from disease Epicentres like Mi
723.
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patrec
7y ago
There are two pretty simple and detailed arguments above why what Ionnidis wrote is preposterous, if you disagree, why not engage with them?
724.
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patrec
7y ago
The problem is that the more cases you have, the higher the likelihood that you will need to end up with multiple strains and need more than one vaccine, which may be fatal to eradication.
725.
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patrec
7y ago
And male vs female variance in general would appear to be strong evidence that something is going on.
726.
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patrec
7y ago
I will go out on a limb here (I'm hardly a domain expert) and make the following prediction: In retrospect this will be seen as the moment when peer perception of Ioannidis fell from major scientific figure to reckless (or worse!) frau
727.
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patrec
7y ago
People keep saying so, but I have yet to see compelling evidence. Can you provide some? For what it's worth, I think eradicating something world-wide that has already spread widely beyond the relatively competent and affluent countries
728.
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by
patrec
7y ago
Since what you wrote is true (you could have a gene where one allele increases observed phenotypic variance and another decreases it; in fact I'm pretty sure such genes exists), I suspect the people downvoted you did so because they&#x
729.
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patrec
7y ago
Great, then you must be the perfect person to alleviate the following additional concerns I still have: - Isn't there a significant risk that immunity after infection might wear of too soon after infection for herd immunity to be pract
730.
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patrec
7y ago
Your scepticism would be more intelligent if there weren't also South Korea and Taiwan. Basically all countries that made any real effort at suppression seem to be doing comparably well ATM, no? And I think both of them may rank higher
731.
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patrec
7y ago
Most people who compare Italy (and soon the UK) to say, South Korea or Taiwan would probably disagree with you. Also, whilst you might not mind a few hundred thousand or million dead pensioners, I assume at least some of them would rather s
732.
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patrec
7y ago
I still can't believe that no western country is even capable of creating freaking face masks at scale (and no, doesn't need to be N95).
733.
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patrec
7y ago
> Containment is moot in this case Please be very careful when writing such things. Containment has already been proven to work even with almost 100k known infected, now down to basically zero new infections. The new cases in China see
734.
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patrec
7y ago
A thousand times this! The viral growth is not the only exponential thing here, the costs of bringing down R0 are also highly non-linear, and it works both for and against us. Against: it is going to be much more expensive to get R0 from 1.
735.
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patrec
7y ago
I don't see why. Can you spell out what's inherently slow apart from the observation phases?
736.
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patrec
7y ago
And I think this is likely to be a limiting factor in more cases. If anyone reading this has good channels to companies, organizations or individuals to pitch this idea to, please do.
737.
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patrec
7y ago
I'm not sure how this would contradict what I wrote, I totally agree that the observation of the patients is the one thing where you can't really speed things up much. It's inherently serial, no matter how much money and manp
738.
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patrec
7y ago
Walter is completely right. Under extreme circumstances (worst pandemic in 100 years) our risk thresholds should obviously shift. You can't cut corners too much and there is an inherent serial component, because if you want to vacci
739.
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patrec
7y ago
Since there are likely plenty of rich people reading HN: you can probably help your country and save lives at minor expected cost to yourself by just giving this guy a legally binding promise to pay him for unwanted masks should he ramp up
740.
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patrec
7y ago
Well, did you stop reading the article past the pic, do it yourself from scratch and finish in 10 minutes, or did you just nod along each time?
741.
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patrec
7y ago
> Because it isn’t possible to screen every single person entering a country like the UK Why not? Personally, if I were put before the choice of not having more people enter my country than I can screen or killing off 1M+ of my electorat
742.
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patrec
7y ago
> If BoJo really tries to execute that plan, he has to be stopped. But that's the beauty of the plan, it functions as its own dead man's switch.
743.
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patrec
7y ago
> so preventing breakouts is just flat out not possible Why not?
744.
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patrec
7y ago
Merkel apparently is trying to (or tried to), but was more coy about it. But none of the technocratic Asian governments seem to.
745.
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patrec
7y ago
Nope, SARS and MERS are way deadlier than Covid-19, not just in initial estimates. South Korea tested hundreds of thousands of people and we have the Diamond Princess. That makes it unlikely that we are overestimating CFR by an order of mag
746.
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patrec
7y ago
The problem is they might reap much more than intended. I'd really like to see estimates of how many economically productive members of society will get caught out by the fact that sadly they can't have life-saving treatment after
747.
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patrec
7y ago
I think you kinda missed the part where the UK is trying very hard to infect the majority of the population and China is trying very hard to stop more infections from taking place. Successfully it seems. > So no, there won't be &q
748.
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patrec
7y ago
Death of thousands or more??? You are living in some pleasant fantasy! Back in reality, the UK wants to infect about a cool 40M people (for the herd immunity!). Last I heard they expect 50% (20M) to get it in a 3 week interval. Meanwhile th
749.
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patrec
7y ago
China – always one step ahead!
750.
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patrec
7y ago
9. So in addition to the >1M dead this strategy likely entails (several 100k in the case of a fatality rate below South Korea's 0.6%, which sounds completely unachievable), what long term damage scenarios for the survivors has been
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