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oaktrout
searching PlanetScale…
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91.
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oaktrout
4y ago
Large population based studies tell us what caused the cancer. If smokers are 20x more likely to get lung cancer we know that smoking causes cancer.
92.
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oaktrout
4y ago
I think if people didn't have smoking / drinking / overeating as coping mechanisms they might find healthy alternatives like exercise / altruism / creativity. Look at seventh day Adventists in Loma Linda (not a memb
93.
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oaktrout
4y ago
I would look into varenicline (chantix), talk with a doctor. I know some people will bring up incredibly rare side effects as reasons not to try, but I think those are sort of like plane crashes, they happen sometimes and cause a very visce
94.
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oaktrout
4y ago
Obesity also contributes to inflammation,fat cells release pro-inflammatory adipokines.
95.
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oaktrout
4y ago
POCUS is used commonly in my experience and there are large amounts of curriculum devoted to it. We haven't had affordable access to POCUS for decades so I don't see how doctors have refused to learn it for decades.
96.
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oaktrout
4y ago
Excess fat -> insulin resistance -> higher fasting insulin.
97.
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oaktrout
4y ago
Re studying only women: it's a problem when you are making a claim about all cause mortality but failing to mention that it's all cause mortality "in women", you can't generalize. "Are you saying that the autho
98.
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oaktrout
4y ago
"Is it coming from someone with a lot of experience evaluating the protocols of epidemiological studies?" It is, but I prefer to not involve my own credentials as a boring appeal to authority and focus on the argument at hand. I m
99.
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oaktrout
4y ago
"Outside online" does not seem like an unbiased source on this issue. Asking four questions that pertain to something does not make a good measure of that something. Agree to disagree on this one. This is coming from someone who s
100.
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oaktrout
4y ago
I agree. I think it's also reductionist to say sun avoidance increases mortality, at least based on the evidence we have.
101.
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oaktrout
4y ago
My issue with the study wasn't study size or duration, it was the questionarre. People who go to holiday in the mountains or go swimming are probably healthier. They could have just asked about sun exposure "how many days in the p
102.
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oaktrout
4y ago
True in women according to that study. Also they didn't ask specifically about sun exposure avoidance, they asked things like "Do you go abroad on holiday to swim and sunbathe". People on dialysis don't go abroad and peo
103.
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oaktrout
4y ago
I'm not sure tbh, this really isn't my area of expertise. Sorry, I was hopeful someone more knowledgeable would reply.
104.
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oaktrout
4y ago
I agree. I see this sort of misunderstanding commonly here. Hacker news is filled with individuals who think computers can solve all our problems, and at the same time they lack the most basic understanding of the complexities of biology.
105.
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oaktrout
4y ago
I have to think that computational models will be infinitely cheaper than animal testing. If they worked as well as animal testing surely some for profit pharmaceutical company would leverage them to reap enormous profits. Because this is n
106.
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oaktrout
4y ago
The paper linked by bsdz checks for one specific cardiac side effect, it is not anywhere close to being a model for cardiotoxicity as a whole, a very important distinction.
107.
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oaktrout
4y ago
I briefly scanned the paper. This is not a computer model for cardiotoxicity as a whole, it's a model for one very specific type of cardiotoxicity. These things may have their uses, bit they are a long way from replacing animal testing
108.
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oaktrout
4y ago
It's also worth noting that cerebrovascular disease can cause a dementia with symptoms just like alzheimers (without actually having alzheimers). It's literally called vascular dementia: https://en.m.wikipedia.org/
109.
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oaktrout
4y ago
For the arms at least, they make UV protective shirts, they are essentially just a lightweight loose breathable fabric. Worth considering if you aren't familiar with them.
110.
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oaktrout
4y ago
A surgeon might choose to let you die in a bland but predictable way if they think they might be sued for their heroic (but perhaps not RCT proven safe) efforts. I agree that bad surgeons and immoral practices need to be stopped but the lin
111.
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oaktrout
4y ago
Agree, and at some point you have to let the inexperienced surgeon operate or in 20 years there will be no experienced surgeons. Not to mention the "inexperienced" guy has been doing it for 4 years.
112.
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oaktrout
4y ago
This is fascinating, neurosurgery really is something else. I am surprised it takes that long to close.
113.
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oaktrout
4y ago
From the paper "Race prediction performance was also robust across models trained on single equipment and single hospital location on the chest x-ray and mammogram datasets"
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oaktrout
4y ago
I recall seeing a paper in the early 2010s with an algorithm that could discriminate between white and Asian based on head MRI images. I'm having trouble finding it now, but this finding to me is not too surprising.
115.
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oaktrout
5y ago
I would wager you know many people who have gotten better after seeing a "professional". Mental health isn't often discussed openly so you would probably be shocked at how many high functioning people are on SSRIs (doctors, l
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oaktrout
5y ago
I didnt find any info on 5HT2C in the linked source above, not saying what you've said isn't true, just that I was interested and didn't find much info.
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oaktrout
5y ago
This will get buried but as far as ssris having "really bad side-effects for most people that take them", I think thats not true. I see lots of people on SSRIs, most deny having any side effects, some have minor side effects that
118.
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oaktrout
5y ago
The first flu vaccine came about in 1945. Knowing as much as we did about viruses then, you might think we would have a cure for influenza (or the common cold) by now. Here we are almost 80 years later... big data may be coming but if takes
119.
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oaktrout
5y ago
I've heard similar anecdotes about missing the highs. The thing is the highs can be scary also, with people doing things like spending their life savings or engaging in dangerous activities.
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oaktrout
5y ago
Medical licensing exams in the US are randomized within the same sitting, even having two examiners in the same room receiving entirely different questions (not just random question ordering).
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