nonbel

69 ms·

601.
by nonbel 8y ago
What did they say? That intermittent fasting and basically lowering blood sugar seems to slow/prevent tumor growth? Whats wrong with that?
602.
by nonbel 8y ago
>"The mechanism by which a tumor suppresses and evades immune response is tremendously complex." What is so complex about it? >"Every type of response for every category of tumor cell must be decoded. As well as every e
603.
by nonbel 8y ago
People have a really wrong idea about "experimental" medical treatments. Its much easier to break something you don't understand than fix it, and our knowledge of the human body is so rudimentary it is effectively zero. The o
604.
by nonbel 8y ago
Isn't "easier to learn and apply" usually code for "slower and more difficult to optimize"?
605.
by nonbel 8y ago
>"That sounds like a lot to me." It sounds like a lot because you are adding up energy used by many, many people all around the world. Lots of things "sound like a lot" when you do that. Why not do the same calculatio
606.
by nonbel 8y ago
>"That is INSANE." Is it? What have you compared that to? At least some people like bitcoin/etc, who likes the new reddit layout that requires transferring 60x more data than necessary (using HN is an example of an environ
607.
by nonbel 8y ago
Why are you speaking in riddles?
608.
by nonbel 8y ago
That doesn't seem like much of an issue to me when the alternative is nobody trusts the results.
609.
by nonbel 8y ago
>"Media is hyping the fear of 'election hacking' to the point where people I know personally want everything to be done manually, no machine or computer involvement at all." Whats wrong with this?
610.
by nonbel 8y ago
This isnt something even remotely close to happening.
611.
by nonbel 8y ago
>"No, no, no! It says the model is powerful enough to compute any computable function. This is where the optimality of universal measures comes from." Then the model must be whatever function it is computing/approximating
612.
by nonbel 8y ago
Yes, humans cannot synthesize sodium but it also doesn't degrade, its only lost due to excretion. Regardless, it is an essential component of the diet, unlike sugar. Plants (and every other known form of life) also cannot synthesize mi
613.
by nonbel 8y ago
>"Yes, and that model is a universal computer, as stated in the articles I linked to." This basically says "the model is anything at all". From the first example in the first link, I see the probability in that case i
614.
by nonbel 8y ago
1) You seem to think you are disagreeing with me, but I never said everyone was the same. I said the point is to find a diet where you feel satisfied without consuming too many calories. Some people might love sugar too much and need to cut
615.
by nonbel 8y ago
In that case, wouldn't "a fully functional human body model" mean an artificial human, which is even harder to develop than a computational model? Or they do exist, already. All humans are a fully functional human body model.
616.
by nonbel 8y ago
>"knowing the amount of effort expended in the rest of the field of medical research today ... it is indeed surprising that nobody has bothered to even try to produce a human body model. The feat probably wouldn't even require
617.
by nonbel 8y ago
This is opposite of the productive approach. The starting point should be "what diet can you eat that makes you feel satisfied after the appropriate amount of calories for your body/lifestyle". The proportion of carbs in the
618.
by nonbel 8y ago
They said "we still don't have a fully functional human body model", as if one was pending or expected to be developed already.
619.
by nonbel 8y ago
This isn't in conflict with what I said but ok. Possibly, what evidence are you basing this on?
620.
by nonbel 8y ago
> ">Sorry, but I really have no patience for these purely "philosophical" discussions of probability. I’m not sure what you mean by this. Can you elaborate?" There is nothing in that link that I can apply to a pro
621.
by nonbel 8y ago
"The fact that we still don't have a fully functional human body model to test theories on, doesn't help either." What does this mean?
622.
by nonbel 8y ago
>"sugar is essential for the human body" Sugar is not essential to the diet, the body can make it from fat and protein. Ie, https://en.wikipedia.org/wiki/Gluconeogenesis However, afaik, you cannot live wit
623.
by nonbel 8y ago
Sorry, but I really have no patience for these purely "philosophical" discussions of probability. I don't see a single equation on that page but I can assure you that to compute a probability you are assuming some form of the
624.
by nonbel 8y ago
>"Bayeseian probability is always probability within a model." Is there a conception of probability that is not conditional on a model?
625.
by nonbel 8y ago
> "The problem I have with the Bayesian definition of probability is that it isn't a definition, is it?" You'll have to clarify what exactly your problem with the concept is here. > "So what does the 1 in 1&#
626.
by nonbel 8y ago
Yes, it is well known there are a certain number of mutations (indels, point mutations, chromosomal rearrangements, etc) per division and cells in a dish divide many, many times. Why would anyone think they would not harbour significant lev
627.
by nonbel 8y ago
>"Long thought to be genetically stable and identical, cancer cell lines harbor significant levels of genetic variation, which may help explain why it can be hard to reproduce findings in cell line-based research." Who thought
628.
by nonbel 8y ago
Previous HN discussion: Original Paper: https://news.ycombinator.com/item?id=14912382 Original Critique: https://news.ycombinator.com/item?id=15147377
629.
Did CRISPR really fix a genetic mutation in these human embryos?(nature.com)
2 points by nonbel 8y ago|1 comments
630.
by nonbel 8y ago
>"Many Big Pharma companies literally have their PR department run their clinical trial studies. If someone is surprised that a paper sounds like a press release they have a lot to learn how "science" works today." I

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